SPITZ_DROME - dbPTM
SPITZ_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPITZ_DROME
UniProt AC Q01083
Protein Name Protein spitz
Gene Name spi
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 234
Subcellular Localization Cell membrane
Single-pass type I membrane protein . Endoplasmic reticulum membrane
Single-pass type I membrane protein . Golgi apparatus membrane
Single-pass type I membrane protein . Relocalization to the Golgi apparatus and the plasma membran
Protein Description Ligand for the EGF receptor (Gurken). Involved in a number of unrelated developmental choices, for example, dorsal-ventral axis formation, glial migration, sensory organ determination, and muscle development. It is required for photoreceptor determination..
Protein Sequence MHSTMSVQHGLVALVLIGCLAHPWHVEACSSRTVPKPRSSISSSMSGTALPPTQAPVTSSTTMRTTTTTTPRPNITFPTYKCPETFDAWYCLNDAHCFAVKIADLPVYSCECAIGFMGQRCEYKEIDNTYLPKRPRPMLEKASIASGAMCALVFMLFVCLAFYLRFEQRAAKKAYELEQELQQEYDDDDGQCECCRNRCCPDGQEPVILERKLPYHMRLEHALMSFAIRRSNKL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
29S-palmitoylationHPWHVEACSSRTVPK
CCHHHHHHCCCCCCC
2.1016459296
74N-linked_GlycosylationTTTTPRPNITFPTYK
CCCCCCCCCCCCCCC
47.41-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPITZ_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPITZ_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPITZ_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
TNKS_DROMETnksphysical
15710747
ABRU_DROMEabphysical
15710747
GALT6_DROMEpgant6physical
15710747
GGNB2_DROMECG2182physical
15710747
FSH_DROMEfs(1)hphysical
15710747
GSTS1_DROMEGstS1physical
15710747
HNF4_DROMEHnf4physical
15710747
NETB_DROMENetBphysical
15710747
OVO_DROMEovogenetic
10421370
DECA_DROMEdppgenetic
10934021
SALM_DROMEsalmgenetic
11171397
VG_DROMEvggenetic
9927598
EGFR_DROMEEgfrgenetic
8929534
RHOM_DROMErhogenetic
10570464
SPY_DROMEstygenetic
10089881
VEIN_DROMEvngenetic
8824589
VEIN_DROMEvngenetic
25336739
HID_DROMEWgenetic
11832242
EGFR_DROMEEgfrphysical
16459296
GIL_DROMEaosphysical
16459296

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPITZ_DROME

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Related Literatures of Post-Translational Modification

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