| UniProt ID | VG_DROME | |
|---|---|---|
| UniProt AC | Q26366 | |
| Protein Name | Protein vestigial | |
| Gene Name | vg | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 453 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Involved in determining which thoracic imaginal disk cells will form wings and halteres, perhaps by interacting with other nuclear regulatory proteins. When in combination with scalloped (sd), it acts as a transcriptional activation complex that regulates gene expression in the wing. Binding to sd switches the DNA target selectivity of sd. Required and sufficient for cell proliferation at the dorsal/ventral (D/V) boundary of the wing imaginal disk. Also required for cell proliferation in the wing imaginal disk, mediated via activation of E2f. By interacting with Dhfr, may control genes involved in DNA replication.. | |
| Protein Sequence | MAVSCPEVMYGAYYPYLYGRAGTSRSFYQYERFNQDLYSSSGVNLAASSSASGSSHSPCSPILPPSVSANAAAAVAAAAHNSAAAAVAVAANQASSSGGIGGGGLGGLGGLGGGPASGLLGSNVVPGSSSVGSVGLGMSPVLSGAAGHSLHSSHRTHAHSLAHAHTHPHSHTHTHTHQTKEEDLIVPRSEAEARLVGSQQHQHHNESSCSSGPDSPRHAHSHSHPLHGGGGATGGPSSAGGTGSGGGDGGGTGAIPKNLPALETPMGSGGGGLAGSGQGQAQYLSASCVVFTNYSGDTASQVDEHFSRALNYNNKDSKESSSPMSNRNFPPSFWNSNYVHPIPAPTHHQVSDLYGTATDTGYATDPWVPHAAHYGSYAHAAHAHAAHAHAYHHNMAQYGSLLRLPQQYASHGSRLHHDQQTAHALEYSSYPTMAGLEAQVAQVQESSKDLYWF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of VG_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VG_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VG_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VG_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RL38_DROME | RpL38 | genetic | 10353901 | |
| SCAL_DROME | sd | genetic | 9869635 | |
| SCAL_DROME | sd | genetic | 17110491 | |
| SCAL_DROME | sd | genetic | 20685961 | |
| DECA_DROME | dpp | genetic | 16414040 | |
| WNTG_DROME | wg | genetic | 9570768 | |
| WNTG_DROME | wg | genetic | 12441303 | |
| SALM_DROME | salm | genetic | 22094701 | |
| TRA1_DROME | Nipped-A | genetic | 10353901 | |
| APTE_DROME | ap | genetic | 12485165 | |
| EGFR_DROME | Egfr | genetic | 20685961 | |
| YAP1_DROME | yki | genetic | 18258486 | |
| DIAP1_DROME | th | genetic | 14526388 | |
| FNG_DROME | fng | genetic | 16643882 | |
| E2F1_DROME | E2f | genetic | 14526388 | |
| SERR_DROME | Ser | genetic | 9501029 | |
| SCAL_DROME | sd | physical | 9869635 | |
| MEF2_DROME | Mef2 | physical | 18987343 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
