dbPTM

SNAP_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SNAP_DROME
UniProt AC	Q23983
Protein Name	Alpha-soluble NSF attachment protein
Gene Name	alphaSnap {ECO:0000312\|FlyBase:FBgn0250791}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	292
Subcellular Localization	Cytoplasmic vesicle . Membrane Peripheral membrane protein .
Protein Description	Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Also between the endosome and phagosome..
Protein Sequence	MGDNEQKALQLMAEAEKKLTQQKGFLGSLFGGSNKVEDAIECYQRAGNMFKMSKNWTKAGECFCEAATLHARAGSRHDAGTCYVDASNCYKKVDVESAVNCLMKSIDIYTDMGRFTMAAKHHQSIAEMYESDPNNLAKSIQHYEQAADYFKGEESVSSANKCMLKVAQYAAQLEDYEKAISIYEQVAASSLESSLLKYSAKEYFFRAALCHLSVDLLNAQHAIEKYAQQYPAFQDSREFKLIKVLCENLEEQNIEGFTEAVKDYDSISRLDQWYTTILLRIKKAADEDPDLR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
28	Phosphorylation	QQKGFLGSLFGGSNK HCCCCHHHHHCCCCH	23.75	21082442
243	Ubiquitination	SREFKLIKVLCENLE HHHHHHHHHHHHCHH	39.32	31113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SNAP_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SNAP_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SNAP_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GOSR2_DROME	Membrin	physical	22036573
NSF2_DROME	Nsf2	genetic	15102912
STX1A_DROME	Syx1A	genetic	15102912
NSF1_DROME	comt	genetic	15102912
STX5_DROME	Syx5	physical	12435359
STX1A_DROME	Syx1A	physical	12414991

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SNAP_DROME

Related Literatures of Post-Translational Modification