USE1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: USE1_DROME
• UniProt AC: Q9VSU7
• Protein Name: Vesicle transport protein USE1
• Gene Name: Use1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 250
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type IV membrane protein .
• Protein Description: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER (By similarity). Required for protein secretion..
• Protein Sequence: MATKLNVNIRTLLANCEELAKSEQNFWRLQKFIKSLDTMLAELEAMGDPQSVKRIPGYLERLQALKISTGYADVPGSTTKTPSQSSAVSETGENALKEIRQLQNSKYHNELRKELLQDSDALRRRRGADESSSSSGSANVQETSGENMNQAAKYYTNAQEKITEHMLSLTRNLKEQTETANRIIRRDTEVVSRSAGMADRNINSLGKEAEKLEQHSKKAYKCWLWLMIAFVIATFIGMVLFMKIMKKKKS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
188	Phosphorylation	NRIIRRDTEVVSRSA HHHHHHCHHHHHHHH	28.94	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of USE1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of USE1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of USE1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SNAP_DROME	alphaSnap	physical	22036573
GOSR2_DROME	Membrin	physical	22036573
GOSR1_DROME	Gos28	physical	22036573

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.