dbPTM

GOSR1_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GOSR1_DROME
UniProt AC	Q9VE50
Protein Name	Golgi SNAP receptor complex member 1
Gene Name	Gos28
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	232
Subcellular Localization	Golgi apparatus membrane Single-pass type IV membrane protein.
Protein Description	Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor (By similarity)..
Protein Sequence	MGGSSYDVLRKQARSLENEIDLKLVAFSKIGAGSGGGGSGGLGGVDTSPLLGEHVFDSLSEEIEQMLEKLSSLNESMSDLPASGAAAMHTLQRHREILQGYRQEFNKICANHTMRIEREELLRGSGLATSSGSPSISGLNRREMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQAFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Phosphorylation	SGAAAMHTLQRHREI HHHHHHHHHHHHHHH	16.11	19429919
129	Phosphorylation	LRGSGLATSSGSPSI HCCCCCCCCCCCCCC	28.59	30478224
133	Phosphorylation	GLATSSGSPSISGLN CCCCCCCCCCCCCCC	19.88	29892262
135	Phosphorylation	ATSSGSPSISGLNRR CCCCCCCCCCCCCHH	30.96	25749252

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GOSR1_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GOSR1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GOSR1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GOSR2_DROME	Membrin	physical	22036573
SNAP_DROME	alphaSnap	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GOSR1_DROME

Related Literatures of Post-Translational Modification