| UniProt ID | MAM1_YEAST | |
|---|---|---|
| UniProt AC | P40065 | |
| Protein Name | Monopolin complex subunit MAM1 | |
| Gene Name | MAM1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 302 | |
| Subcellular Localization | Nucleus . Localizes to kinechores during late pachytene. | |
| Protein Description | Component of the monopolin complex which promotes monoorientation during meiosis I, required for chromosome segregation during meiosis.. | |
| Protein Sequence | MREKRTISNKDTNYLKFPNKLQRYSRFLSRKISNTSPEKQPKKNIKEHCLSSYHKEHSVKPKQNSGNVAAKEDKDTQHLQNNVANEEATECLTRSNLKKLQEKIFDRELNDIACDHCLCSTENRRDIKYSRLWFLFELEMSENWNENLRLSCYNKYVYSAIDESWKMENILLKEQEKHYEYFPIGQLLIPNNIDYTNKQKRKENIEDLTIEIDSIIETNHQKKRFLPQSVLIKREDEIAFDDFHLDARKVLNDLSATSENPFSSSPNTKKIKSKGKTLEVVPKKKNKKIIGALERKLHIDEN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Acetylation | EKRTISNKDTNYLKF CCCCCCCCCCCCCCC | 60.17 | 25381059 | |
| 24 | Phosphorylation | FPNKLQRYSRFLSRK CCHHHHHHHHHHHHH | 7.40 | 28889911 | |
| 25 | Phosphorylation | PNKLQRYSRFLSRKI CHHHHHHHHHHHHHH | 20.81 | 28889911 | |
| 29 | Phosphorylation | QRYSRFLSRKISNTS HHHHHHHHHHHCCCC | 28.90 | 28889911 | |
| 33 | Phosphorylation | RFLSRKISNTSPEKQ HHHHHHHCCCCCCCC | 36.77 | 27214570 | |
| 35 | Phosphorylation | LSRKISNTSPEKQPK HHHHHCCCCCCCCCC | 38.58 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MAM1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MAM1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MAM1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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