MAM_DROME - dbPTM
MAM_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAM_DROME
UniProt AC P21519
Protein Name Neurogenic protein mastermind
Gene Name mam
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 1594
Subcellular Localization Nucleus . Chromosome .
Protein Description May have a regulatory function possibly in association with the Notch gene product..
Protein Sequence MDAGGLPVFQSASQAAAVAQQQQQQQQQQQQHLNLQLHQQHLGLHLQQQQQLQLQQQQHNAQAQQQQIQVQQQQQQQQQQQQQQHSPYNANLGATGGIAGITGGNGAGGPTNPGAVPTAPGDTMPTKRMPVVDRLRRRMENYRRRQTDCVPRYEQAFNTVCEQQNQETTVLQKRFLESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQHQQAQTMLAGQLQSSVHVQQKFLKRPAEDVDNGPDSFEPPHKLPNNNNNSNSNNNNGNANANNGGNGSNTGNNTNNNGNSTNNNGGSNNNGSENLTKFSVEIVQQLEFTTSAANSQPQQISTNVTVKALTNTSVKSEPGVGGGGGGGGGGGSGNNNNNGGGGGGGNGNNNNNGGDHHQQQHQQQQQQQGGGLGGLGNNGRGGGPGGMATGPGGVAGGLGGMGMPPNMMSAQQKSALGNLANLVECKREPDHDFPDLGSLDKDGGGGQFPGFPDLLGDDNSENNDTFKDLINNLQDFNPSFLDGFDEKPLLDIKTEDGIKVEPPNAQDLINSLNVKSEGGLGHGFGGFGLGLDNPGMKMRGGNPGNQGGFPNGPNGGTGGAPNAGGNGGNSGNLMSEHPLAAQTLKQMAEQHQHKNAMGGMGGFPRPPHGMNPQQQQQQQQQQQQQQAQQQHGQMMGQGQPGRYNDYGGGFPNDFGLGPNGPQQQQQAQQQQPQQQHLPPQFHQQKGPGPGAGMNVQQNFLDIKQELFYSSQNDFDLKRLQQQQAMQQQQQQQHHQQQQQQQQPKMGGVPNFNKQQQQQQVPQQQLQQQQQQQQQQQQQQQQQYSPFSNQNPNAAANFLNCPPRGGPNGNQQPGNLAQQQQQPGAGPQQQQQRGNAANGQQNNPNAGPGGNTPNAPQQQQQQSTTTTLQMKQTQQLHISQQGGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQQQPGGTNGPNPQQQQQQPHGGNAGGGVGVGVGVGVGNGGPNPGQQQQQPNQNMSNANVPSDGFSLSQSQSMNFNQQQQQQAAAQQQQVQPNMRQRQTQAQAAAAAAAAAAQAQAAANASGPNVPLMQQPQVGVGVGVGVGVGVGVGNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQMGGPMNPMQMNPNAAGPTAQQMMMGSGAGGPGQVPGPGQGPNPNQAKFLQQQQMMRAQAMQQQQQHMSGARPPPPEYNATKAQLMQAQMMQQTVGGGGVGVGGVGVGVGVGGVGGANGGRFPNSAAQAAAMRRMTQQPIPPSGPMMRPQHAMYMQQHGGAGGGPRTGMGVPYGGGAGGPMGGPQQQQRPPNVQVTPDGMPMGSQQEWRHMMMTQQQTQMGFGGPGPGGPMRQGPGGFNGGNFMPNGAPNGAAGSGPNAGGMMSGPNVPQMQLTPAQMQQQLMRQQQQQQQQQQQHMGPGAANNMQMQQLLQQQQSGGGGNMMASQMQMTSMHMTQTQQQITMQQQQQFVQSTTTTTHQQQQMMQMGPGGGGGGGGPGSANNNNGGGGGGAAGGGNSASTIASASSISQTINSVVANSNDFGLEFLDNLPVDSNFSTQDLINSLDNDNFNLQDFNMP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
494PhosphorylationDLLGDDNSENNDTFK
HHCCCCCCCCCHHHH
49.0129892262

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MAM_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAM_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAM_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RL38_DROMERpL38genetic
10353901
TOPRS_DROMEToporsphysical
15710747
DHB4_DROMEMfe2physical
15710747
LETM1_DROMELetm1physical
15710747
CALR_DROMECrcphysical
15710747
FAS1_DROMEFas1physical
15710747
DYN_DROMEshiphysical
15710747
TENA_DROMETen-aphysical
15710747
ARM_DROMEarmgenetic
10545243
SGG_DROMEsgggenetic
10545243
NOTCH_DROMENgenetic
10545243
NOTCH_DROMENgenetic
22046261
DTX_DROMEdxgenetic
10545243
DSH_DROMEdshgenetic
10545243
SBNO_DROMEsnogenetic
11536431
AFF4_DROMElilligenetic
23550128
WNTG_DROMEwggenetic
10545243
SUH_DROMESu(H)genetic
7954795
SUH_DROMESu(H)genetic
10545243
TRA1_DROMENipped-Agenetic
10353901
TRA1_DROMENipped-Agenetic
16508010
ECR_DROMEEcRgenetic
23550128
PABP2_DROMEPabp2genetic
23550128
SCA_DROMEscagenetic
18073442
EMC_DROMEemcgenetic
23550128
FRIZ2_DROMEfz2genetic
10545243
PSN_DROMEPsngenetic
11536431
RL13A_DROMERpL13Agenetic
16326033
TAD2B_DROMEAda2bgenetic
16508010
PUM_DROMEpumgenetic
23550128
DL_DROMEDlgenetic
10545243
DL_DROMEDlgenetic
16326033
HLES_DROMEHgenetic
10545243
SERR_DROMESergenetic
10545243
CUT_DROMEctgenetic
10545243
LOLA1_DROMElolagenetic
23550128
LOLA2_DROMElolagenetic
23550128
LOLA3_DROMElolagenetic
23550128
LOLA4_DROMElolagenetic
23550128
LOLA6_DROMElolagenetic
23550128
LOLA5_DROMElolagenetic
23550128
DOM_DROMEdomgenetic
16508010
PP2A_DROMEmtsgenetic
18073442
NIPB_DROMENipped-Bgenetic
10353901
NOTCH_DROMENphysical
15704125
NOTCH_DROMENphysical
21737682
SUH_DROMESu(H)physical
15704125
SUH_DROMESu(H)physical
21737682
SUH_DROMESu(H)physical
27404588

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAM_DROME

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Related Literatures of Post-Translational Modification

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