TENA_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TENA_DROME
• UniProt AC: Q9VYN8
• Protein Name: Teneurin-a
• Gene Name: Ten-a {ECO:0000312|FlyBase:FBgn0267001}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 3004
• Subcellular Localization: Cell projection, axon. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, synaptosome. Membrane ; Single-pass membrane protein . Localizes in the cell body and axon of neuronal cells. Localizes at neuromuscular junction.
• Protein Description: Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a homophilic and heterophilic synaptic cell adhesion molecule that drives synapse assembly. Promotes bi-directional trans-synaptic signaling with ten-m to organize neuromuscular synapses..
• Protein Sequence: MTMKSMKYSDCDTIMDGYNPVPPPLPRRVPPVRNIYAEPFAHEPNHSSRLGGHPQQMPQSMSTGSNTIGHGGIDRGGVGLPMGAGTMPGGVGGGPGGVAGGGPQVGVGPPGSGNGGNCQISGSQPLVMPGFPLRNSHSAHAPHYSPYSPSRFHIDKRCQHRCSWKCLSIALIFVSVVLTAMLAYFAAVSSMKPNMDSTNCILVQDVKSQPHDLRGGLAKSNEKGVATAFPTEESIQTSTSDHGQNGHGLMNPSAGSGGSNSGIQQQLLLQQQQPHSINQPLTPLDATNTHLQDHHQLTYGGALPGGVGGIGMSGGGIMNGGLNGGLGGQLMQQPGGGLNGHHHQALQPQLGGVVELKEFNEAYHATIPAYQFWTLEFRNKHPAFIRFNFTLPWGAHFAVYSRRNVAPSVTQHDFVEFIKGGRLDSHLRHRRSSANATTTGQDMELYRQDKDQSAESAQDQDSEQDESRSFDSSESYDVETPLDTAKQHLQRIGKPQSHWVNKRSAGDGLPALDVDAMTVNVSLLQYLDTGLWFISVYNDELVAHSVSLLAEEAEGVSTTCPNDCSGRGSCYLGKCDCIDGYQGVDCSKSVCPVLCSAHGHYGGGVCHCEEGWKGAECDIPVGECEVPNCSSHGRCIEGECHCERGWKGPYCDQHDCLDPLCSGHGTCVAGQCYCKAGWQGEDCGTIDQQVYQCLPGCSEHGTYDLETGQCVCERHWTGPDCSQAVCSLDCGRNGVCESGKCRCNSGWTGNLCDQLPCDSRCSEHGQCKNGTCVCSQGWNGRHCTLPGCENGCSRHGQCTLENGEYRCDCIEGWAGRDCSIALELNCKDNIDNDGDGMTDCSDSECCSHPACSEHIMCLSSNDPVEVLLRKQPPSVTASFYQRVKFLIEENSVQSYAHMDEYSENRVSVMRGQVITPQGLGIVGIRVSVDRDSRFGFTLTRQGGWFDVLVNGGGAVTLQFQRSPFRPLTRTVFVPWNRIVVLPPVQMQLSDDDETTSRNIKVAPLNPALTFLNSIHYHTADEANDASKVCMDHDHEKLRPQLISTWMPNGVGAMPGKRVIFAETQIVQESIQIPGSDLHLTYQSSQASGYLSIVRMRLTGETIPPTLTHVHVGVEIEGALHVKTYEADPSLVHTFAWNKRNVYRQKVYGVTVARISVGYQHSTCQSPVWIAQTAKLQGYDVDISDIGGWGLDIHHHYNFHEGILQKGDGSTLHMKEYPRTVKVVMGTGLQRPLTCPDYCNGVAKDAKLLTPIALATGPDGSLYVGDFNLVRRITPDGKVYTILQLSATQVSYQYYLAVSPADGHLYISDPERHQILRLVRLEKVKDPSINSDPVVGSGQRCIPGDEGNCGDGGPALLARLSHPKGLAIAADRTMYIADGTNIRAVDPKGVIHTLIGHHGHHNHWSPAPCSGTLMANQAQLQWPTGLALSPLDGSLHFIDDRLVLRLTSDMKIRVVAGTPLHCSNGGQDGRVNKTGADNVLGTVLAMAFSPFGNLYIADSDSRRVNSIRVVDTAGNMRYFAGKQEGTGSQTCDCAIGGGSNGSATNSGVGGAGGSAYSTTVNPTRPNGGTTPTTPSGGNGNGNGNGSSATSSGGSVGGSNGSGGGANGGACICAGGIALSTGTGSSSGSNGGGTLASIVGSGGLMSTGPTTTTTVLLGAKTTAAGIGAATLNDDGTLSNAETLLSSNARFQAISAIAVAQDGVINVADQGSLHVLALEHYLPSHDENGEFHIPFPPSSEIYVFNRYGQHVATKDLTSGKTRYSFLYSKNTSFGRLSTVTDASGNKIQFLRDYSNVVSSIENTQDHKSEIQINGIGIMTKLSEKGRQEIELDYDSNTGLLNSRSSGGETYIYQYDEFGRVTGMILPSGEIVRITSQLADSQGLTVYVHASVESLFSRERIAGEANELLVLGGVRSTFLKRGQAHADAELKANNTLVIHGDNGVVVEASAVARHPLLEAALPVEAEMLAMWSHQSVTMGEGLTNSMYSVYSLVGDVRNPQQTLNREIWVNQSRVIGVEFDQFTNRETFYDARRTPILIVAYDQSGLPKSYYPTNGYPVNITYDRFNRVEGWAWGPAELKYSYDRHGLLSEITSQQDGIVSFVYNDWNLVSEIGLASQRKFVLQYDDAGGLRHVVLPSGTRHSFSMQTSIGFIRCTYTPPGSTRAYLQHYSHAGALLQTILPGDGARIVYRYNAAGQLTEVVHGDGRSEFQYNEATGMPSTVSHTERELEYRWDFEYAAGLLAEERIDYVAKTGLSNAKFSYEYDSQLRVVALQGRIGGQSLPTQAFAYDPRTGRPSLIGQFRFSQPAQNQTQLHDGTASFTRTVDGRFQTQRMALAIHRLEVFRMEFSYGVHGRISQTRTYTRNMAVNSYTNVKNYTWDCDGQLVGVEAQEPWGFRYDDNGNLLSLTYRGNTIPMEYNAQDRIVKFGEGQYKYDARGLVAQNAREERFHYNTQGLLVRASKRGRFDVRYYYDHLKRLTTRKDNFGNVTQFFYTNQQRPYEVSQIYSPRDGKLMSLTYDDVGHLIYAQVYRHKYYVATDQSGTPLMLFNQYGEGIREIMRSPFGHIVYDSNPYLYLPIDFCGGILDQVTTLVHMGDGRVYDPLIGQWMSPDWQRVAERIITPTRLHLYRFNGNDPINVGHERHYPEDFAAWMRTLGYNVGNLVPQLARDLWQPPALWGRPPANPVALNLRRPFDNIPTMAVESGFLAHLNVRRMSDFEQLSAPPRSALKCDVMDPSPKTIGSDTEPPFGKGIVVSRTADGQAIVSSVPAANAIYRDVYTSVFNRSKLLPFTFVVHNAQQDSFFFVKEDAWRATEDRQQLKRLQGQVNTTFHEITREATVGSGPAGAANGGAGSSSSSSSSSGGGSSSNTGNYLDVKIHGAHAIINLRYGTTVAKEQQRLMHHAKLTAVRKAWHREKEALRSGLTTALEWSQQETDEILKQSYANNYEGEYIHDVNLYPELAEDPYNIKFVKKKGATGGAAGVPNSRRRRRRSTDLIQEEEEELHREADC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of TENA_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TENA_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TENA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TENA_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TENM_DROME	Ten-m	genetic	22425994
TENA_DROME	Ten-a	physical	22425994
TENA_DROME	Ten-a	physical	12175511
TENM_DROME	Ten-m	physical	22425994

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.