dbPTM

ENO_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ENO_DROME
UniProt AC	P15007
Protein Name	Enolase
Gene Name	Eno
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	500
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MSWTASVFLRTSTTSMKFLRLRWPLPRIPQNKSANVAPRFRSKSAVSQLSSGFKFVQIRKSTCDSNEMTIKAIKARQIYDSRGNPTVEVDLTTELGLFRAAVPSGASTGVHEALELRDNDKANYHGKSVLKAVGHVNDTLGPELIKANLDVVDQASIDNFMIKLDGTENKSKFGANAILGVSLAVAKAGAAKKGVPLYKHIADLAGNKEIILPVPAFNVINGGSHAGNKLAMQEFMILPTGATSFTEAMKMGSEVYHHLKNVIKAKFGLDATAVGDEGGFAPNIQSNKEALNLISDAIAKAGYTGKIEIGMDVAASEFYKDGQYDLDFKNEKSDKSQWLPADKLANLYQEFIKDFPIVSIEDPFDQDHWEAWSNLTGCTDIQIVGDDLTVTNPKRIATAVEKKACNCLLLKVNQIGTVTESIAAHLLAKKNGWGTMVSHRSGETEDSFIGDLVVGLSTGQIKTGAPCRSERLAKYNQILRIEEEIGAGVKFAGKSFRKPQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
156	Phosphorylation	LDVVDQASIDNFMIK CCEECHHHCCCEEEE	25.49	27794539
300	Acetylation	LISDAIAKAGYTGKI HHHHHHHHCCCCCCE	35.91	21791702
494	Acetylation	AGVKFAGKSFRKPQ- CCCEECCCCCCCCC-	42.88	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ENO_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ENO_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ENO_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SCRT_DROME	st	physical	14605208
SXL_DROME	Sxl	physical	14605208
CALR_DROME	Crc	physical	22036573
PDI_DROME	Pdi	physical	22036573
SH3BG_DROME	Sh3beta	physical	22036573
NLP_DROME	Nlp	physical	22036573
THIO2_DROME	Trx-2	physical	22036573
FKB12_DROME	FK506-bp2	physical	22036573
NACA_DROME	Nacalpha	physical	22036573
MOEH_DROME	Moe	physical	22036573
UCHL_DROME	Uch	physical	22036573
TRXR1_DROME	Trxr-1	physical	22036573
HCD2_DROME	scu	physical	22036573
GPDA_DROME	Gpdh	physical	22036573
INO1_DROME	Inos	physical	22036573
PGK_DROME	Pgk	physical	22036573
PCNA_DROME	PCNA	physical	22036573
IF5A_DROME	eIF-5A	physical	22036573
TPM2_DROME	Tm2	physical	22036573
ATP5J_DROME	ATPsyn-Cf6	physical	22036573
6PGD_DROME	Pgd	physical	22036573
1433E_DROME	14-3-3epsilon	physical	22036573
EF1D_DROME	eEF1delta	physical	22036573
MLR_DROME	Mlc2	physical	22036573
TCTP_DROME	Tctp	physical	22036573
G3P2_DROME	Gapdh2	physical	22036573
VDAC_DROME	porin	physical	22036573
GSTS1_DROME	GstS1	physical	22036573
SODC_DROME	Sod	physical	22036573
SODM_DROME	Sod2	physical	22036573
PSA6_DROME	Prosalpha1	physical	22036573
MLC1_DROME	Mlc1	physical	22036573
ATPB_DROME	ATPsyn-beta	physical	22036573
PPIA_DROME	Cyp1	physical	22036573
RS27A_DROME	RpS27A	physical	24292889
CISY_DROME	kdn	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ENO_DROME

Related Literatures of Post-Translational Modification