| UniProt ID | PDI_DROME | |
|---|---|---|
| UniProt AC | P54399 | |
| Protein Name | Protein disulfide-isomerase | |
| Gene Name | Pdi | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 496 | |
| Subcellular Localization | Endoplasmic reticulum lumen . | |
| Protein Description | Participates in the folding of proteins containing disulfide bonds.. | |
| Protein Sequence | MKFLICALFLAASYVAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGRQAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALDSFVFGVSSNADVIAKYEAKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDFNHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTRIFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQELPEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFLDANGEVADSEPVEETEEEEEAPKKDEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 68 | Acetylation | ALAPEYAKAAQQLAE HHHHHHHHHHHHHHH | 43.27 | 21791702 | |
| 76 | Acetylation | AAQQLAEKESPIKLA HHHHHHHCCCCCCEE | 58.86 | 21791702 | |
| 106 | Acetylation | VRGYPTLKFFRSGSP HCCCCCEEECCCCCC | 44.96 | 21791702 | |
| 170 | Acetylation | DLESEEAKTFTKVAN CCCCHHHHHHHHHHH | 47.66 | 21791702 | |
| 270 | Acetylation | REGGHIEKYVDPLKE CCCCCHHHCCCHHHH | 50.39 | 21791702 | |
| 444 | Acetylation | ISSFPTIKYFRKEDN ECCCCCEEEEECCCC | 40.59 | 21791702 | |
| 478 | Phosphorylation | ANGEVADSEPVEETE CCCCCCCCCCCCCCH | 33.78 | 29892262 | |
| 484 | Phosphorylation | DSEPVEETEEEEEAP CCCCCCCCHHHHHCC | 34.88 | 19429919 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PDI_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PDI_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PDI_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NLP_DROME | Nlp | physical | 22036573 | |
| SH3BG_DROME | Sh3beta | physical | 22036573 | |
| THIO2_DROME | Trx-2 | physical | 22036573 | |
| NACA_DROME | Nacalpha | physical | 22036573 | |
| TRXR1_DROME | Trxr-1 | physical | 22036573 | |
| HCD2_DROME | scu | physical | 22036573 | |
| TCTP_DROME | Tctp | physical | 22036573 | |
| OFUT2_DROME | O-fut2 | physical | 22036573 | |
| EF1D_DROME | eEF1delta | physical | 22036573 | |
| INO1_DROME | Inos | physical | 22036573 | |
| YC17_DROME | CG16817 | physical | 22036573 | |
| TERA_DROME | TER94 | physical | 22036573 | |
| IF5A_DROME | eIF-5A | physical | 22036573 | |
| CH60_DROME | Hsp60 | physical | 22036573 | |
| 1433E_DROME | 14-3-3epsilon | physical | 22036573 | |
| PSA6_DROME | Prosalpha1 | physical | 22036573 | |
| UGGG_DROME | Ugt | physical | 22036573 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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