| UniProt ID | INO1_DROME | |
|---|---|---|
| UniProt AC | O97477 | |
| Protein Name | Inositol-3-phosphate synthase | |
| Gene Name | Inos | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 565 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | ||
| Protein Sequence | MKPTNNSTLEVISPKVQVDDEFITTDYDYQTSHVKRTADGQLQVHPQTTSLKIRTGRHVPKLGVMLVGWGGNNGSTLTAALEANRRQLKWRKRTGVQEANWYGSITQASTVFIGSDEDGGDVYVPMKELLPMVEPDNIIVDGWDISGLHLGDAMRRAEVLDVALQDQIYDQLAQLRPRPSIYDPDFIAANQSDRADNVIRGTRLEQYEQIRKDIRDFRERSGVDSVIVLWTANTERFADVQPGLNTTSQELIASLEANHSEVSPSTIFAMASIAEGCTYINGSPQNTFVPGLIQLAEEKNVFIAGDDFKSGQTKIKSVLVDFLVGAGIKPVSIASYNHLGNNDGKNLSAPQQFRSKEISKSNVVDDMVASNRLLYGPDEHPDHVVVIKYVPYVGDSKRAMDEYTSEIMMGGHNTLVIHNTCEDSLLATPLILDLVILGELSTRIQLRNAEKESAPWVPFKPVLSLLSYLCKAPLVPQGSQVVNSLFRQRAAIENILRGCIGLPPISHMTLEQRFDFSTITNEPPLKRVKILGQPCSVESVTNGKKLHANGHSNGSAKLATNGNGH | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Phosphorylation | NSTLEVISPKVQVDD CCCEEEECCCEEECC | 24.68 | 21082442 | |
| 52 | Ubiquitination | HPQTTSLKIRTGRHV CCCCCEEEEECCCCC | 29.88 | 31113955 | |
| 348 | Phosphorylation | NNDGKNLSAPQQFRS CCCCCCCCCCHHHHC | 47.50 | 22817900 | |
| 359 | Phosphorylation | QFRSKEISKSNVVDD HHHCHHHHHCCCHHH | 30.99 | 21082442 | |
| 479 | Phosphorylation | APLVPQGSQVVNSLF CCCCCCCHHHHHHHH | 17.98 | 21082442 | |
| 484 | Phosphorylation | QGSQVVNSLFRQRAA CCHHHHHHHHHHHHH | 19.78 | 21082442 | |
| 536 | Phosphorylation | KILGQPCSVESVTNG EECCCCCEEEEECCC | 35.29 | 19429919 | |
| 552 | Phosphorylation | KLHANGHSNGSAKLA EEEECCCCCCCCEEC | 44.26 | 19429919 | |
| 555 | Phosphorylation | ANGHSNGSAKLATNG ECCCCCCCCEECCCC | 26.87 | 19429919 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of INO1_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of INO1_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of INO1_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SH3BG_DROME | Sh3beta | physical | 22036573 | |
| YC17_DROME | CG16817 | physical | 22036573 | |
| NACA_DROME | Nacalpha | physical | 22036573 | |
| TERA_DROME | TER94 | physical | 22036573 | |
| ITPA_DROME | CG8891 | physical | 22036573 | |
| WDR1_DROME | flr | physical | 22036573 | |
| IF5A_DROME | eIF-5A | physical | 22036573 | |
| EF1D_DROME | eEF1delta | physical | 22036573 | |
| SIL1_DROME | CG10420 | physical | 22036573 | |
| RS10B_DROME | RpS10b | physical | 22036573 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "An integrated chemical, mass spectrometric and computational strategyfor (quantitative) phosphoproteomics: application to Drosophilamelanogaster Kc167 cells."; Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D.,Juenger M.A., Eng J.K., Aebersold R., Tao W.A.; Mol. Biosyst. 3:275-286(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-536, AND MASSSPECTROMETRY. | |
