dbPTM

YC17_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YC17_DROME
UniProt AC	Q9VH95
Protein Name	Uncharacterized protein CG16817
Gene Name	CG16817
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	184
Subcellular Localization
Protein Description
Protein Sequence	MSAAAGLIPPPVSWAQRNDLIYVIIDVECKDIEHKVTEKTFTFKGVNVLDPSKKYEVTLNFLHEVDPEKVTSKNIGRCLEFTIPKKAAGPYWSSLTTDKTKLHFLKANFAKWRDESDDEEGDQKDNSMFGNFLNSPGGDWNNKFDDFNVDDEEEDSDDNIPSLSQNDEDDEEGGEGDKEKKPAA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
39	Acetylation	IEHKVTEKTFTFKGV CCCCEEECEEEEECE	39.30	21791702
116	Phosphorylation	FAKWRDESDDEEGDQ HHCCCCCCCCCCCCC	55.43	21082442
127	Phosphorylation	EGDQKDNSMFGNFLN CCCCCCCCCHHHHHC	26.14	19429919
135	Phosphorylation	MFGNFLNSPGGDWNN CHHHHHCCCCCCCCC	27.37	19429919
156	Phosphorylation	VDDEEEDSDDNIPSL CCCCCCCCCCCCCCC	50.58	21082442
162	Phosphorylation	DSDDNIPSLSQNDED CCCCCCCCCCCCCCC	36.53	19429919
164	Phosphorylation	DDNIPSLSQNDEDDE CCCCCCCCCCCCCCC	31.13	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YC17_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YC17_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YC17_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MMD4_DROME	mod(mdg4)	physical	14605208
NACA_DROME	Nacalpha	physical	22036573
TERA_DROME	TER94	physical	22036573
SIL1_DROME	CG10420	physical	22036573
PSMD9_DROME	CG9588	physical	22036573
SPTCA_DROME	alpha-Spec	physical	22036573
CARM1_DROME	Art4	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YC17_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116; SER-127; SER-135;SER-156 AND SER-162, AND MASS SPECTROMETRY.	18327897 [Abstract]
"An integrated chemical, mass spectrometric and computational strategyfor (quantitative) phosphoproteomics: application to Drosophilamelanogaster Kc167 cells."; Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D.,Juenger M.A., Eng J.K., Aebersold R., Tao W.A.; Mol. Biosyst. 3:275-286(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-116 AND SER-156, ANDMASS SPECTROMETRY.	17372656 [Abstract]