| UniProt ID | PCNA_DROME | |
|---|---|---|
| UniProt AC | P17917 | |
| Protein Name | Proliferating cell nuclear antigen | |
| Gene Name | PCNA | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 260 | |
| Subcellular Localization | Nucleus . Colocalizes with crm in polytene nuclei during embryogenesis. | |
| Protein Description | This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.. | |
| Protein Sequence | MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 59 | Acetylation | LRSDGFDKFRCDRNL ECCCCCCCEECCCCC | 32.23 | 21791702 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PCNA_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PCNA_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PCNA_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PCNA_DROME | PCNA | physical | 15575970 | |
| IMDH_DROME | ras | physical | 15575970 | |
| PDI_DROME | Pdi | physical | 22036573 | |
| NACA_DROME | Nacalpha | physical | 22036573 | |
| NLP_DROME | Nlp | physical | 22036573 | |
| HCD2_DROME | scu | physical | 22036573 | |
| SH3BG_DROME | Sh3beta | physical | 22036573 | |
| INO1_DROME | Inos | physical | 22036573 | |
| FKB12_DROME | FK506-bp2 | physical | 22036573 | |
| MOEH_DROME | Moe | physical | 22036573 | |
| THIO2_DROME | Trx-2 | physical | 22036573 | |
| UCHL_DROME | Uch | physical | 22036573 | |
| EF1D_DROME | eEF1delta | physical | 22036573 | |
| IF5A_DROME | eIF-5A | physical | 22036573 | |
| PCNA_SCHPO | pcn1 | physical | 7780738 | |
| FEN1_DROME | Fen1 | physical | 9705499 | |
| PCNA_DROME | PCNA | physical | 17087725 | |
| PCNA_DROME | PCNA | physical | 23545643 | |
| KMT5A_DROME | pr-set7 | physical | 24806961 | |
| SUUR_DROME | SuUR | physical | 23149855 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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