SODM_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SODM_DROME
• UniProt AC: Q00637
• Protein Name: Superoxide dismutase [Mn], mitochondrial
• Gene Name: Sod2
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 217
• Subcellular Localization: Mitochondrion matrix.
• Protein Description: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems..
• Protein Sequence: MFVARKISPNCKPGVRGKHTLPKLPYDYAALEPIICREIMELHHQKHHQTYVNNLNAAEEQLEEAKSKSDTTKLIQLAPALRFNGGGHINHTIFWQNLSPNKTQPSDDLKKAIESQWKSLEEFKKELTTLTVAVQGSGWGWLGFNKKSGKLQLAALPNQDPLEASTGLIPLFGIDVWEHAYYLQYKNVRPSYVEAIWDIANWDDISCRFQEAKKLGC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
73	Acetylation	KSKSDTTKLIQLAPA HCCCCHHHHHHHHHH	45.76	21791702
118	Acetylation	KAIESQWKSLEEFKK HHHHHHHHCHHHHHH	37.21	21791702
124	Acetylation	WKSLEEFKKELTTLT HHCHHHHHHHHHHEE	48.93	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SODM_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SODM_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SODM_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UCHL_DROME	Uch	physical	22036573
OGG1_DROME	Ogg1	genetic	24516391
SODC_DROME	Sod	genetic	24656823

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.