PGK_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PGK_DROME
• UniProt AC: Q01604
• Protein Name: Phosphoglycerate kinase
• Gene Name: Pgk
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 415
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MAFNKLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDGNKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKIVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIARAKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTGGGASLELLEGKTLPGVAALTSA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAFNKLSIENLDLA -CCCCCCCHHCCCCC	29.48	27794539
29	Acetylation	VDFNVPIKEGKITSN EEECCCCCCCCCCCC	55.11	21791702
73	Acetylation	PDGNKNIKYTLAPVA CCCCCCCCEEEHHHH	41.39	21791702
129	Acetylation	FYVEEEGKGLDASGG EEEEECCCCCCCCCC	60.63	21791702
266	Acetylation	EGSKIVEKLVEKAKK HHHHHHHHHHHHHHH	47.11	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PGK_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PGK_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PGK_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TERA_DROME	TER94	physical	22036573
FTZF1_DROME	ftz-f1	physical	25242320

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.