UniProt ID | RBP2_MOUSE | |
---|---|---|
UniProt AC | Q9ERU9 | |
Protein Name | E3 SUMO-protein ligase RanBP2 | |
Gene Name | Ranbp2 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 3053 | |
Subcellular Localization | Nucleus . Nucleus membrane . Nucleus, nuclear pore complex . Nucleus envelope . Detected in diffuse and discrete intranuclear foci. Cytoplasmic filaments. | |
Protein Description | E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I. Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates. Binds single-stranded RNA (in vitro). May bind DNA. Component of the nuclear export pathway. Specific docking site for the nuclear export factor exportin-1 (By similarity). Sumoylates PML at 'Lys-490' which is essential for the proper assembly of PML-NB. Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.. | |
Protein Sequence | MRRSKADVERYIASVQGSAPSPREKSMKGFYFAKLYYEAKEYDLAKKYISTYINVQERDPKAHRFLGLLYEVEENIDKAVECYKRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCKGEDGWNKLFDLIQSELYARPDDIHVNIRLVELYRSNKRLKDAVAHCHEADRNTALRSSLEWNLCVVQTLKEYLESLQCLDSDKSTWRATNKDLLLAYANLMLLTLSTRDVQEGRELLESFDSALQSVKSSVGGNDELSATFLETKGHFYMHVGSLLLKMGQQSDIQWRALSELAALCYLVAFQVPRPKVKLIKGEAGQNLLETMAHDRLSQSGHMLLNLSRGKQDFLKEVVESFANKSGQSALCDALFSSQSSKERSFLGNDDIGNLDGQVPDPDDLARYDTGAVRAHNGSLQHLTWLGLQWNSLSTLPAIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVIYTSHLQLKEKCNSHHTSYQPLCLPLPVCRQLCTERQKTWWDAVCTLIHRKALPGTSAKLRLLVQREINSLRGQEKHGLQPALLVHWAQSLQKTGSSLNSFYDQREYIGRSVHYWRKVLPLLKMIRKKNSIPEPIDPLFKHFHSVDIQASEIGEYEEDAHITFAILDAVNGNIEDAMTAFESIKNVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLIRILDDSDSNTSVVQKLPVPLESVKEMLNSVMQELEDYSEGGTLYKNGCWRSADSELKHSTPSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSNNSASPHRWPAEPYGQDPAPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGPVYGMNRLPPQQHIYAYSQQMHTPPVQSSSACMFSQEMYGPPLRFESPATGILSPRGDDYFNYNVQQTSTNPPLPEPGYFTKPPLVAHASRSAESKVIEFGKSNFVQPMQGEVIRPPLTTPAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVAQPPSTAYSNSESLLGLLTSDKPLQGDGYSGLKPISGQASGSRNTFSFGSKNTLTENMGPNQQKNFGFHRSDDMFAFHGPGKSVFTTAASELANKSHETDGGSAHGDEEDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDGESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQNILKALGTNTSTAPNHTLRIVKESATQDNKDICKADGGNLNFEFQIVKKEGPYWNCNSCSFKNAATAKKCVSCQNTNPTSNKELLGPPLVENGFAPKTGLENAQDRFATMTANKEGHWDCSVCLVRNEPTVSRCIACQNTKSASSFVQTSFKFGQGDLPKSVDSDFRSVFSKKEGQWECSVCLVRNERSAKKCVACENPGKQFKEWHCSLCSVKNEAHAIKCVACNNPVTPSLSTAPPSFKFGTSEMSKPFRIGFEGMFAKKEGQWDCSLCFVRNEASATHCIACQYPNKQNQPTSCVSAPASSETSRSPKSGFEGLFPKKEGEWECAVCSVQNESSSLKCVACEASKPTHKPHEAPSAFTVGSKSQSNESAGSQVGTEFKSNFPEKNFKVGISEQKFKFGHVDQEKTPSFAFQGGSNTEFKSIKDGFSFCIPVSADGFKFGIQEKGNQEKKSEKHLENDPSFQAHDTSGQKNGSGVVFGQTSSTFTFADLAKSTSREGFQFGKKDPNFKGFSGAGEKLFSSQSGKVAEKANTSSDLEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEISQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQVKVTDEENASSGADAPSASDTTAKQNPDNTGPALEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKSPAKLNQSGASVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQTMKGTERVWVWTACDFADGERKIEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSHLSTPRESPCGKIAIAVLEETTRERTDLTQGDEVIDTTSEAGETSSTSETTPKAVVSPPKFVFGSESVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKNSNSEMTSRVQSGSEGKVKPDKCELPQNSDIKQSSDGKVKNLSAFSKENSSTSYTFKTPEKAQEKSKPEDLPSDNDILIVYELTPTPEQKALAEKLLLPSTFFCYKNRPGYVSEEEEDDEDYEMAVKKLNGKLYLDDSEKPLEENLADNDKECVIVWEKKPTVEERAKADTLKLPPTFFCGVCSDTDEDNGNGEDFQSELRKVCEAQKSQNEKVTDRVGIEHIGETEVTNPVGCKSEEPDSDTKHSSSSPVSGTMDKPVDLSTRKETDMEFPSKGENKPVLFGFGSGTGLSFADLASSNSGDFAFGSKDKNFQWANTGAAVFGTQTTSKGGEDEDGSDEDVVHNEDIHFEPIVSLPEVEVKSGEEDEEVLFKERAKLYRWDRDVSQWKERGIGDIKILWHTMKKYYRILMRRDQVFKVCANHVITKAMELKPLNVSNNALVWTASDYADGEAKVEQLAVRFKTKEMTESFKKKFEECQQNIIKLQNGHTSLAAELSKDTNPVVFFDVCADGEPLGRIIMELFSNIVPQTAENFRALCTGEKGFGFKNSIFHRVVPDFICQGGDITKYNGTGGQSIYGDKFDDENFDLKHTGPGLLSMANYGQNTNSSQFFITLKKAEHLDFKHVVFGFVKDGMDTVRKIESFGSPKGSVSRRICITECGQL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
11 | Phosphorylation | SKADVERYIASVQGS CHHHHHHHHHHHCCC | 6.32 | 25619855 | |
14 | Phosphorylation | DVERYIASVQGSAPS HHHHHHHHHCCCCCC | 12.86 | 25619855 | |
18 | Phosphorylation | YIASVQGSAPSPREK HHHHHCCCCCCHHHH | 21.66 | 25619855 | |
21 | Phosphorylation | SVQGSAPSPREKSMK HHCCCCCCHHHHHCC | 35.98 | 26824392 | |
50 | Phosphorylation | DLAKKYISTYINVQE HHHHHHHHHHCCHHH | 16.45 | 29472430 | |
51 | Phosphorylation | LAKKYISTYINVQER HHHHHHHHHCCHHHC | 20.89 | 29472430 | |
52 | Phosphorylation | AKKYISTYINVQERD HHHHHHHHCCHHHCC | 5.45 | 29472430 | |
128 | Phosphorylation | AAKLFPGSPAIYKLK HHHHCCCCHHHHHHH | 16.05 | 26745281 | |
132 | Phosphorylation | FPGSPAIYKLKEQLL CCCCHHHHHHHHHHH | 16.63 | 26643407 | |
175 | Phosphorylation | NIRLVELYRSNKRLK EHHHHHHHHCCCCHH | 9.86 | 29472430 | |
177 | Phosphorylation | RLVELYRSNKRLKDA HHHHHHHCCCCHHHH | 32.90 | 29472430 | |
225 | Ubiquitination | LQCLDSDKSTWRATN CCCCCCCHHHHHHCC | 54.45 | 22790023 | |
335 | Ubiquitination | RPKVKLIKGEAGQNL CCCCEEEECCHHHHH | 62.22 | 22790023 | |
352 | Phosphorylation | TMAHDRLSQSGHMLL HHHHHHHHHHCCHHH | 24.16 | 29472430 | |
354 | Phosphorylation | AHDRLSQSGHMLLNL HHHHHHHHCCHHHHC | 27.56 | 29472430 | |
362 | Phosphorylation | GHMLLNLSRGKQDFL CCHHHHCCCCCHHHH | 37.60 | 29472430 | |
379 | Ubiquitination | VVESFANKSGQSALC HHHHHCCCCCHHHHH | 53.16 | 22790023 | |
396 | Ubiquitination | LFSSQSSKERSFLGN HHCCCCHHHHHCCCC | 63.49 | 22790023 | |
550 | Ubiquitination | ALPGTSAKLRLLVQR CCCCCHHHHHHHHHH | 33.63 | 27667366 | |
756 | Phosphorylation | VMQELEDYSEGGTLY HHHHHHHHCCCCCEE | 10.15 | 25159016 | |
757 | Phosphorylation | MQELEDYSEGGTLYK HHHHHHHCCCCCEEE | 41.93 | 25159016 | |
770 | Phosphorylation | YKNGCWRSADSELKH EECCCCCCCCCCCCC | 16.36 | 25777480 | |
773 | Phosphorylation | GCWRSADSELKHSTP CCCCCCCCCCCCCCC | 44.54 | 21183079 | |
778 | Phosphorylation | ADSELKHSTPSPTKY CCCCCCCCCCCCCCC | 40.19 | 27149854 | |
779 | Phosphorylation | DSELKHSTPSPTKYS CCCCCCCCCCCCCCC | 27.75 | 23684622 | |
781 | Phosphorylation | ELKHSTPSPTKYSLS CCCCCCCCCCCCCCC | 45.34 | 26824392 | |
783 | Phosphorylation | KHSTPSPTKYSLSPS CCCCCCCCCCCCCCC | 47.13 | 23335269 | |
785 | Phosphorylation | STPSPTKYSLSPSKS CCCCCCCCCCCCCCC | 19.81 | 25159016 | |
786 | Phosphorylation | TPSPTKYSLSPSKSY CCCCCCCCCCCCCCC | 24.75 | 25168779 | |
788 | Phosphorylation | SPTKYSLSPSKSYKY CCCCCCCCCCCCCCC | 22.61 | 25521595 | |
790 | Phosphorylation | TKYSLSPSKSYKYSP CCCCCCCCCCCCCCC | 30.75 | 21082442 | |
792 | Phosphorylation | YSLSPSKSYKYSPKT CCCCCCCCCCCCCCC | 31.06 | 25159016 | |
793 | Phosphorylation | SLSPSKSYKYSPKTP CCCCCCCCCCCCCCC | 20.06 | 25777480 | |
795 | Phosphorylation | SPSKSYKYSPKTPPR CCCCCCCCCCCCCCC | 23.21 | 25159016 | |
796 | Phosphorylation | PSKSYKYSPKTPPRW CCCCCCCCCCCCCCH | 18.77 | 23684622 | |
798 | Ubiquitination | KSYKYSPKTPPRWAE CCCCCCCCCCCCHHH | 68.66 | 27667366 | |
799 | Phosphorylation | SYKYSPKTPPRWAED CCCCCCCCCCCHHHC | 41.74 | 25521595 | |
809 | Phosphorylation | RWAEDQNSLLKMICQ CHHHCHHHHHHHHHH | 29.46 | 25266776 | |
832 | Phosphorylation | MQELKLNSNNSASPH HHHHHCCCCCCCCCC | 48.07 | 25159016 | |
835 | Phosphorylation | LKLNSNNSASPHRWP HHCCCCCCCCCCCCC | 34.08 | 25159016 | |
837 | Phosphorylation | LNSNNSASPHRWPAE CCCCCCCCCCCCCCC | 22.51 | 26824392 | |
896 | Phosphorylation | LRPAANVTPTKGPVY EEECCCCCCCCCCCC | 25.66 | 29472430 | |
898 | Phosphorylation | PAANVTPTKGPVYGM ECCCCCCCCCCCCCC | 38.99 | 29472430 | |
903 | Phosphorylation | TPTKGPVYGMNRLPP CCCCCCCCCCCCCCC | 17.50 | 25159016 | |
915 | Phosphorylation | LPPQQHIYAYSQQMH CCCHHHHHEEECCCC | 9.43 | 22802335 | |
944 | Asymmetric dimethylarginine | EMYGPPLRFESPATG HHHCCCCCCCCCCCC | 38.77 | - | |
944 | Methylation | EMYGPPLRFESPATG HHHCCCCCCCCCCCC | 38.77 | - | |
947 | Phosphorylation | GPPLRFESPATGILS CCCCCCCCCCCCCCC | 19.68 | 21082442 | |
950 | Phosphorylation | LRFESPATGILSPRG CCCCCCCCCCCCCCC | 28.30 | 25619855 | |
954 | Phosphorylation | SPATGILSPRGDDYF CCCCCCCCCCCCCCC | 15.61 | 25521595 | |
960 | Phosphorylation | LSPRGDDYFNYNVQQ CCCCCCCCCCCCCCC | 9.85 | 25159016 | |
990 | Phosphorylation | PPLVAHASRSAESKV CCCEEECCCCCCCHH | 19.53 | 22324799 | |
996 | Acetylation | ASRSAESKVIEFGKS CCCCCCCHHHCCCCC | 38.44 | 23806337 | |
1015 | Asymmetric dimethylarginine | PMQGEVIRPPLTTPA CCCCCEECCCCCCCC | 31.77 | - | |
1015 | Methylation | PMQGEVIRPPLTTPA CCCCCEECCCCCCCC | 31.77 | 24129315 | |
1038 | Phosphorylation | KFNSNFKSNDGDFTF CCCCCCCCCCCCCEE | 35.70 | 26643407 | |
1044 | Phosphorylation | KSNDGDFTFSSPQVV CCCCCCCEECCCEEE | 27.61 | 26643407 | |
1046 | Phosphorylation | NDGDFTFSSPQVVAQ CCCCCEECCCEEEEC | 37.74 | 26643407 | |
1047 | Phosphorylation | DGDFTFSSPQVVAQP CCCCEECCCEEEECC | 18.37 | 26643407 | |
1096 | Phosphorylation | QASGSRNTFSFGSKN CCCCCCCCCCCCCCC | 21.39 | 28066266 | |
1098 | Phosphorylation | SGSRNTFSFGSKNTL CCCCCCCCCCCCCCC | 27.02 | 23684622 | |
1101 | Phosphorylation | RNTFSFGSKNTLTEN CCCCCCCCCCCCCCC | 22.26 | 25521595 | |
1104 | Phosphorylation | FSFGSKNTLTENMGP CCCCCCCCCCCCCCC | 38.50 | 19060867 | |
1106 | Phosphorylation | FGSKNTLTENMGPNQ CCCCCCCCCCCCCCC | 24.23 | 25367039 | |
1122 | Phosphorylation | KNFGFHRSDDMFAFH CCCCCCCCCCEEEEC | 29.41 | 23684622 | |
1134 | Phosphorylation | AFHGPGKSVFTTAAS EECCCCCHHHHHHHH | 28.51 | 25367039 | |
1137 | O-linked_Glycosylation | GPGKSVFTTAASELA CCCCHHHHHHHHHHH | 17.23 | 30059200 | |
1137 | Phosphorylation | GPGKSVFTTAASELA CCCCHHHHHHHHHHH | 17.23 | 25367039 | |
1138 | O-linked_Glycosylation | PGKSVFTTAASELAN CCCHHHHHHHHHHHC | 14.57 | 30059200 | |
1138 | Phosphorylation | PGKSVFTTAASELAN CCCHHHHHHHHHHHC | 14.57 | 21183079 | |
1141 | Phosphorylation | SVFTTAASELANKSH HHHHHHHHHHHCCCC | 30.58 | 25521595 | |
1147 | Phosphorylation | ASELANKSHETDGGS HHHHHCCCCCCCCCC | 26.77 | 25521595 | |
1150 | Phosphorylation | LANKSHETDGGSAHG HHCCCCCCCCCCCCC | 34.22 | 25521595 | |
1154 | Phosphorylation | SHETDGGSAHGDEED CCCCCCCCCCCCCCC | 23.71 | 27087446 | |
1214 | Malonylation | ERGIGNVKILRHKTS HCCCCCEEEEEECCC | 39.77 | 26320211 | |
1214 | Ubiquitination | ERGIGNVKILRHKTS HCCCCCEEEEEECCC | 39.77 | 27667366 | |
1243 | Phosphorylation | ICANHYISPDMKLTP HHHHCCCCCCCCCCC | 14.00 | 23608596 | |
1306 | O-linked_Glycosylation | LKALGTNTSTAPNHT HHHHCCCCCCCCCHH | 27.56 | 30059200 | |
1307 | O-linked_Glycosylation | KALGTNTSTAPNHTL HHHCCCCCCCCCHHE | 25.33 | 30059200 | |
1349 | Phosphorylation | IVKKEGPYWNCNSCS EEECCCCCCCCCCCC | 21.80 | 20116462 | |
1376 | Phosphorylation | CQNTNPTSNKELLGP CCCCCCCCCHHHCCC | 47.35 | 21183079 | |
1407 | Phosphorylation | QDRFATMTANKEGHW HHHHHHCCCCCCCCE | 23.79 | - | |
1438 | Phosphorylation | IACQNTKSASSFVQT EEECCCCCCHHHCHH | 31.20 | 28725479 | |
1440 | Phosphorylation | CQNTKSASSFVQTSF ECCCCCCHHHCHHHE | 31.25 | 26745281 | |
1441 | Phosphorylation | QNTKSASSFVQTSFK CCCCCCHHHCHHHEE | 29.20 | 22817900 | |
1445 | Phosphorylation | SASSFVQTSFKFGQG CCHHHCHHHEECCCC | 30.72 | 29176673 | |
1446 | Phosphorylation | ASSFVQTSFKFGQGD CHHHCHHHEECCCCC | 14.89 | 24719451 | |
1457 | Phosphorylation | GQGDLPKSVDSDFRS CCCCCCCCCCCCHHH | 29.26 | 29514104 | |
1476 | Phosphorylation | KEGQWECSVCLVRNE CCCEEEEEEEEEECH | 12.35 | 28066266 | |
1526 | Phosphorylation | VACNNPVTPSLSTAP EECCCCCCCCCCCCC | 14.39 | 30352176 | |
1528 | Phosphorylation | CNNPVTPSLSTAPPS CCCCCCCCCCCCCCC | 26.11 | 26745281 | |
1530 | Phosphorylation | NPVTPSLSTAPPSFK CCCCCCCCCCCCCCC | 27.19 | 28066266 | |
1531 | Phosphorylation | PVTPSLSTAPPSFKF CCCCCCCCCCCCCCC | 48.77 | 28066266 | |
1535 | Phosphorylation | SLSTAPPSFKFGTSE CCCCCCCCCCCCCCC | 39.75 | 23984901 | |
1545 | Acetylation | FGTSEMSKPFRIGFE CCCCCCCCCEEEEEC | 47.03 | 23954790 | |
1591 | Phosphorylation | PNKQNQPTSCVSAPA CCCCCCCCCCEECCC | 25.62 | 25619855 | |
1592 | Phosphorylation | NKQNQPTSCVSAPAS CCCCCCCCCEECCCC | 21.14 | 25619855 | |
1595 | Phosphorylation | NQPTSCVSAPASSET CCCCCCEECCCCCCC | 32.63 | 25619855 | |
1599 | Phosphorylation | SCVSAPASSETSRSP CCEECCCCCCCCCCC | 27.87 | 23684622 | |
1600 | Phosphorylation | CVSAPASSETSRSPK CEECCCCCCCCCCCC | 47.18 | 23684622 | |
1602 | Phosphorylation | SAPASSETSRSPKSG ECCCCCCCCCCCCCC | 31.24 | 23684622 | |
1603 | Phosphorylation | APASSETSRSPKSGF CCCCCCCCCCCCCCC | 27.06 | 25521595 | |
1605 | Phosphorylation | ASSETSRSPKSGFEG CCCCCCCCCCCCCCC | 36.13 | 25521595 | |
1608 | Phosphorylation | ETSRSPKSGFEGLFP CCCCCCCCCCCCCCC | 52.69 | 23984901 | |
1662 | Phosphorylation | AFTVGSKSQSNESAG CEECCCCCCCCCCCC | 40.30 | 30352176 | |
1664 | Phosphorylation | TVGSKSQSNESAGSQ ECCCCCCCCCCCCCC | 50.05 | 27841257 | |
1670 | Phosphorylation | QSNESAGSQVGTEFK CCCCCCCCCCCCHHH | 22.78 | - | |
1695 | Sumoylation | GISEQKFKFGHVDQE EECCCEEECCCCCCC | 58.43 | 28289178 | |
1706 | Phosphorylation | VDQEKTPSFAFQGGS CCCCCCCCCCCCCCC | 34.14 | - | |
1731 | O-linked_Glycosylation | FSFCIPVSADGFKFG EEEEEEECCCCCEEC | 18.45 | 29407155 | |
1758 | Phosphorylation | KHLENDPSFQAHDTS HHHCCCCCCCCCCCC | 32.62 | 29550500 | |
1764 | Phosphorylation | PSFQAHDTSGQKNGS CCCCCCCCCCCCCCC | 25.53 | 29550500 | |
1765 | Phosphorylation | SFQAHDTSGQKNGSG CCCCCCCCCCCCCCC | 45.33 | 29550500 | |
1790 | Phosphorylation | TFADLAKSTSREGFQ EHHHHHHHCCCCCCC | 26.47 | 23684622 | |
1791 | Phosphorylation | FADLAKSTSREGFQF HHHHHHHCCCCCCCC | 30.97 | 28066266 | |
1792 | Phosphorylation | ADLAKSTSREGFQFG HHHHHHCCCCCCCCC | 35.11 | 30352176 | |
1814 | Acetylation | GFSGAGEKLFSSQSG CCCCCCHHHHCCCCC | 54.65 | 23806337 | |
1820 | Phosphorylation | EKLFSSQSGKVAEKA HHHHCCCCCHHHHHC | 42.39 | 29514104 | |
1829 | Phosphorylation | KVAEKANTSSDLEKD HHHHHCCCCCCCCCC | 34.17 | 23429704 | |
1830 | Phosphorylation | VAEKANTSSDLEKDD HHHHCCCCCCCCCCC | 22.97 | 21082442 | |
1831 | Phosphorylation | AEKANTSSDLEKDDD HHHCCCCCCCCCCCC | 44.14 | 25521595 | |
1840 | Phosphorylation | LEKDDDAYKTEDSDD CCCCCCCCCCCCCCC | 25.99 | 21149613 | |
1842 | Phosphorylation | KDDDAYKTEDSDDIH CCCCCCCCCCCCCCC | 32.14 | 23684622 | |
1845 | Phosphorylation | DAYKTEDSDDIHFEP CCCCCCCCCCCCCEE | 30.83 | 23684622 | |
1898 | Ubiquitination | ERGLGNLKILKNEVN HCCCCCCEEHHHHHH | 50.41 | 22790023 | |
1962 | Ubiquitination | KLEQLAAKFKTPELA HHHHHHHHHCCHHHH | 41.61 | 22790023 | |
1990 | Phosphorylation | LLDIPLQTPHKLVDT HHCCCCCCCCHHCHH | 34.73 | 26824392 | |
1997 | Phosphorylation | TPHKLVDTGRAAKLI CCCHHCHHHHHHHHH | 22.53 | - | |
2012 | Phosphorylation | QRAEEMKSGLKDFKT HHHHHHHHCCCHHHH | 48.31 | 26824392 | |
2018 | Sumoylation | KSGLKDFKTFLTNDQ HHCCCHHHHHHHCCC | 48.80 | 28289178 | |
2029 | Phosphorylation | TNDQVKVTDEENASS HCCCEEECCCCHHCC | 31.79 | 30635358 | |
2035 | Phosphorylation | VTDEENASSGADAPS ECCCCHHCCCCCCCC | 40.67 | 30352176 | |
2036 | Phosphorylation | TDEENASSGADAPSA CCCCHHCCCCCCCCC | 35.27 | 25521595 | |
2042 | Phosphorylation | SSGADAPSASDTTAK CCCCCCCCCCCCCCC | 41.97 | 30635358 | |
2044 | Phosphorylation | GADAPSASDTTAKQN CCCCCCCCCCCCCCC | 39.57 | 30635358 | |
2046 | Phosphorylation | DAPSASDTTAKQNPD CCCCCCCCCCCCCCC | 26.59 | 30635358 | |
2055 | Phosphorylation | AKQNPDNTGPALEWD CCCCCCCCCCCCCCC | 52.50 | 28066266 | |
2074 | Phosphorylation | REDALDDSVSSSSVH CHHHCCCCCCCCCCC | 24.46 | 27742792 | |
2076 | Phosphorylation | DALDDSVSSSSVHAS HHCCCCCCCCCCCCC | 28.58 | 27742792 | |
2077 | Phosphorylation | ALDDSVSSSSVHASP HCCCCCCCCCCCCCC | 25.20 | 27742792 | |
2078 | Phosphorylation | LDDSVSSSSVHASPL CCCCCCCCCCCCCCC | 28.95 | 27742792 | |
2079 | Phosphorylation | DDSVSSSSVHASPLA CCCCCCCCCCCCCCC | 21.62 | 27087446 | |
2083 | Phosphorylation | SSSSVHASPLASSPV CCCCCCCCCCCCCCC | 12.93 | 27087446 | |
2087 | Phosphorylation | VHASPLASSPVRKNL CCCCCCCCCCCCCCC | 42.74 | 27087446 | |
2088 | Phosphorylation | HASPLASSPVRKNLF CCCCCCCCCCCCCCH | 23.08 | 27087446 | |
2100 | Phosphorylation | NLFRFGESTTGFNFS CCHHCCCCCCCCCCC | 31.48 | 30352176 | |
2101 | Phosphorylation | LFRFGESTTGFNFSF CHHCCCCCCCCCCCC | 27.00 | 21659604 | |
2107 | Phosphorylation | STTGFNFSFKSALSP CCCCCCCCCCCCCCC | 32.63 | 26824392 | |
2110 | Phosphorylation | GFNFSFKSALSPSKS CCCCCCCCCCCCCCC | 32.22 | 25159016 | |
2113 | Phosphorylation | FSFKSALSPSKSPAK CCCCCCCCCCCCCCC | 27.18 | 26824392 | |
2115 | Phosphorylation | FKSALSPSKSPAKLN CCCCCCCCCCCCCCC | 42.25 | 27566939 | |
2117 | Phosphorylation | SALSPSKSPAKLNQS CCCCCCCCCCCCCCC | 34.13 | 26824392 | |
2124 | Phosphorylation | SPAKLNQSGASVGTD CCCCCCCCCCCCCCC | 34.94 | 25619855 | |
2127 | Phosphorylation | KLNQSGASVGTDEES CCCCCCCCCCCCCCC | 25.30 | 21082442 | |
2130 | Phosphorylation | QSGASVGTDEESDVT CCCCCCCCCCCCCCC | 37.77 | 25521595 | |
2134 | Phosphorylation | SVGTDEESDVTQEEE CCCCCCCCCCCCHHH | 35.02 | 25521595 | |
2137 | Phosphorylation | TDEESDVTQEEERDG CCCCCCCCCHHHCCC | 34.94 | 25619855 | |
2278 | Phosphorylation | KIFDEAKTAQEKDSL HHHHHHHHHHHHHCC | 40.39 | 25777480 | |
2284 | Phosphorylation | KTAQEKDSLITPHVS HHHHHHHCCCCCCCH | 32.51 | 25619855 | |
2287 | Phosphorylation | QEKDSLITPHVSHLS HHHHCCCCCCCHHCC | 16.79 | 25619855 | |
2291 | Phosphorylation | SLITPHVSHLSTPRE CCCCCCCHHCCCCCC | 18.71 | 25168779 | |
2294 | Phosphorylation | TPHVSHLSTPRESPC CCCCHHCCCCCCCCC | 30.83 | 27087446 | |
2295 | Phosphorylation | PHVSHLSTPRESPCG CCCHHCCCCCCCCCC | 32.50 | 27087446 | |
2299 | Phosphorylation | HLSTPRESPCGKIAI HCCCCCCCCCCHHHH | 27.11 | 27087446 | |
2317 | Phosphorylation | EETTRERTDLTQGDE HHHCCCCCCCCCCCE | 30.52 | 25619855 | |
2320 | Phosphorylation | TRERTDLTQGDEVID CCCCCCCCCCCEEEE | 33.06 | 25619855 | |
2328 | Phosphorylation | QGDEVIDTTSEAGET CCCEEEECCCCCCCC | 22.54 | 25619855 | |
2329 | Phosphorylation | GDEVIDTTSEAGETS CCEEEECCCCCCCCC | 22.33 | 25619855 | |
2330 | Phosphorylation | DEVIDTTSEAGETSS CEEEECCCCCCCCCC | 27.78 | 25521595 | |
2335 | Phosphorylation | TTSEAGETSSTSETT CCCCCCCCCCCCCCC | 27.36 | 25619855 | |
2336 | Phosphorylation | TSEAGETSSTSETTP CCCCCCCCCCCCCCC | 27.58 | 25619855 | |
2337 | Phosphorylation | SEAGETSSTSETTPK CCCCCCCCCCCCCCC | 43.29 | 25619855 | |
2338 | Phosphorylation | EAGETSSTSETTPKA CCCCCCCCCCCCCCE | 30.28 | 25619855 | |
2339 | Phosphorylation | AGETSSTSETTPKAV CCCCCCCCCCCCCEE | 34.59 | 25619855 | |
2341 | Phosphorylation | ETSSTSETTPKAVVS CCCCCCCCCCCEEEC | 48.44 | 27087446 | |
2342 | Phosphorylation | TSSTSETTPKAVVSP CCCCCCCCCCEEECC | 20.81 | 25521595 | |
2348 | Phosphorylation | TTPKAVVSPPKFVFG CCCCEEECCCCEECC | 28.96 | 26824392 | |
2356 | Phosphorylation | PPKFVFGSESVKSIF CCCEECCCHHHHHHH | 18.42 | 25619855 | |
2358 | Phosphorylation | KFVFGSESVKSIFSS CEECCCHHHHHHHCC | 36.22 | 25619855 | |
2364 | Phosphorylation | ESVKSIFSSEKSKPF HHHHHHHCCCCCCCC | 35.60 | 21454597 | |
2365 | Phosphorylation | SVKSIFSSEKSKPFA HHHHHHCCCCCCCCE | 37.99 | 28066266 | |
2368 | Phosphorylation | SIFSSEKSKPFAFGN HHHCCCCCCCCEECC | 41.32 | 23984901 | |
2376 | Phosphorylation | KPFAFGNSSATGSLF CCCEECCCCCCCCCC | 23.02 | 23984901 | |
2377 | Phosphorylation | PFAFGNSSATGSLFG CCEECCCCCCCCCCE | 33.57 | 23984901 | |
2379 | Phosphorylation | AFGNSSATGSLFGFS EECCCCCCCCCCEEE | 29.29 | 23984901 | |
2381 | Phosphorylation | GNSSATGSLFGFSFN CCCCCCCCCCEEEEC | 19.03 | 23984901 | |
2386 | Phosphorylation | TGSLFGFSFNAPLKN CCCCCEEEECCCCCC | 20.26 | 23984901 | |
2411 | Sumoylation | SGSEGKVKPDKCELP CCCCCCCCCCCCCCC | 51.49 | 28289178 | |
2424 | Sumoylation | LPQNSDIKQSSDGKV CCCCCCCCCCCCCCE | 49.47 | 28289178 | |
2435 | Phosphorylation | DGKVKNLSAFSKENS CCCEEEHHHCCCCCC | 36.34 | 25338131 | |
2438 | Phosphorylation | VKNLSAFSKENSSTS EEEHHHCCCCCCCCC | 38.48 | 28725479 | |
2442 | Phosphorylation | SAFSKENSSTSYTFK HHCCCCCCCCCEEEC | 35.76 | 25619855 | |
2443 | Phosphorylation | AFSKENSSTSYTFKT HCCCCCCCCCEEECC | 32.71 | 25619855 | |
2444 | Phosphorylation | FSKENSSTSYTFKTP CCCCCCCCCEEECCH | 26.10 | 25619855 | |
2445 | Phosphorylation | SKENSSTSYTFKTPE CCCCCCCCEEECCHH | 24.91 | 25619855 | |
2446 | Phosphorylation | KENSSTSYTFKTPEK CCCCCCCEEECCHHH | 19.11 | 25619855 | |
2447 | Phosphorylation | ENSSTSYTFKTPEKA CCCCCCEEECCHHHH | 20.58 | 25619855 | |
2450 | Phosphorylation | STSYTFKTPEKAQEK CCCEEECCHHHHHHH | 32.27 | 22942356 | |
2496 | S-palmitoylation | LLPSTFFCYKNRPGY HCCCEEEECCCCCCC | 4.06 | 28526873 | |
2503 | Phosphorylation | CYKNRPGYVSEEEED ECCCCCCCCCCCCCC | 11.95 | 27742792 | |
2505 | Phosphorylation | KNRPGYVSEEEEDDE CCCCCCCCCCCCCCC | 30.70 | 27087446 | |
2514 | Phosphorylation | EEEDDEDYEMAVKKL CCCCCCCHHHHHHHH | 12.93 | 25619855 | |
2563 | Phosphorylation | EERAKADTLKLPPTF HHHHHCCCCCCCCCE | 30.56 | 25619855 | |
2569 | Phosphorylation | DTLKLPPTFFCGVCS CCCCCCCCEEECCCC | 27.66 | 25619855 | |
2576 | Phosphorylation | TFFCGVCSDTDEDNG CEEECCCCCCCCCCC | 40.93 | 27087446 | |
2578 | Phosphorylation | FCGVCSDTDEDNGNG EECCCCCCCCCCCCC | 25.62 | 27087446 | |
2590 | Phosphorylation | GNGEDFQSELRKVCE CCCHHHHHHHHHHHH | 38.29 | 26643407 | |
2627 | Sumoylation | VTNPVGCKSEEPDSD ECCCCCCCCCCCCCC | 55.78 | 28289178 | |
2628 | Phosphorylation | TNPVGCKSEEPDSDT CCCCCCCCCCCCCCC | 51.79 | 25777480 | |
2633 | Phosphorylation | CKSEEPDSDTKHSSS CCCCCCCCCCCCCCC | 58.87 | 25777480 | |
2635 | Phosphorylation | SEEPDSDTKHSSSSP CCCCCCCCCCCCCCC | 34.31 | 25777480 | |
2636 | Sumoylation | EEPDSDTKHSSSSPV CCCCCCCCCCCCCCC | 46.62 | 28289178 | |
2638 | Phosphorylation | PDSDTKHSSSSPVSG CCCCCCCCCCCCCCC | 33.21 | 27742792 | |
2639 | Phosphorylation | DSDTKHSSSSPVSGT CCCCCCCCCCCCCCC | 34.26 | 27742792 | |
2640 | Phosphorylation | SDTKHSSSSPVSGTM CCCCCCCCCCCCCCC | 41.50 | 27742792 | |
2641 | Phosphorylation | DTKHSSSSPVSGTMD CCCCCCCCCCCCCCC | 31.13 | 26824392 | |
2644 | Phosphorylation | HSSSSPVSGTMDKPV CCCCCCCCCCCCCCC | 31.75 | 27742792 | |
2646 | Phosphorylation | SSSPVSGTMDKPVDL CCCCCCCCCCCCCCC | 18.07 | 27742792 | |
2654 | Phosphorylation | MDKPVDLSTRKETDM CCCCCCCCCCCCCCC | 23.00 | 25619855 | |
2655 | Phosphorylation | DKPVDLSTRKETDME CCCCCCCCCCCCCCC | 53.72 | 25619855 | |
2678 | Phosphorylation | PVLFGFGSGTGLSFA CEEEEECCCCCCCHH | 30.81 | 23984901 | |
2680 | Phosphorylation | LFGFGSGTGLSFADL EEEECCCCCCCHHHH | 36.32 | 26643407 | |
2683 | Phosphorylation | FGSGTGLSFADLASS ECCCCCCCHHHHHCC | 21.52 | 23984901 | |
2729 | Phosphorylation | GGEDEDGSDEDVVHN CCCCCCCCCCCCCCC | 50.58 | 27087446 | |
2746 | Phosphorylation | IHFEPIVSLPEVEVK CCEECCCCCCEEEEC | 38.64 | - | |
2754 | Phosphorylation | LPEVEVKSGEEDEEV CCEEEECCCCCCHHH | 57.52 | 26525534 | |
2788 | Ubiquitination | ERGIGDIKILWHTMK HCCCHHHHHHHHHHH | 36.16 | 22790023 | |
2811 | Glutathionylation | RDQVFKVCANHVITK CHHHHHHHHHHHHHH | 3.02 | 24333276 | |
2835 | Phosphorylation | SNNALVWTASDYADG CCCEEEEEEEHHCCC | 14.59 | 21454597 | |
2837 | Phosphorylation | NALVWTASDYADGEA CEEEEEEEHHCCCCH | 24.63 | 21454597 | |
3033 | Phosphorylation | DTVRKIESFGSPKGS HHHHHHHHCCCCCCC | 38.08 | 28066266 | |
3036 | Phosphorylation | RKIESFGSPKGSVSR HHHHHCCCCCCCCCC | 22.79 | 27600695 |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RBP2_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RBP2_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-781; SER-788 ANDSER-2505, AND MASS SPECTROMETRY. | |
"The phagosomal proteome in interferon-gamma-activated macrophages."; Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.; Immunity 30:143-154(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-954 AND SER-2729, ANDMASS SPECTROMETRY. | |
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2505 AND SER-2729, ANDMASS SPECTROMETRY. | |
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1098; SER-2083;SER-2088; SER-2113; SER-2117; THR-2130; SER-2134; SER-2576 ANDTHR-2578, AND MASS SPECTROMETRY. | |
"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations."; Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.; Mol. Cell. Proteomics 5:914-922(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2505, AND MASSSPECTROMETRY. |