| UniProt ID | NXT2_HUMAN | |
|---|---|---|
| UniProt AC | Q9NPJ8 | |
| Protein Name | NTF2-related export protein 2 | |
| Gene Name | NXT2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 142 | |
| Subcellular Localization | Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. | |
| Protein Description | Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export.. | |
| Protein Sequence | MATSLDFKTYVDQACRAAEEFVNIYYETMDKRRRALTRLYLDKATLIWNGNAVSGLDALNNFFDTLPSSEFQVNMLDCQPVHEQATQSQTTVLVVTSGTVKFDGNKQHFFNQNFLLTAQSTPNNTVWKIASDCFRFQDWSSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MATSLDFKTYV ----CCCCCHHHHHH | 19.19 | 24719451 | |
| 9 (in isoform 3) | Phosphorylation | - | 28.86 | 24719451 | |
| 20 (in isoform 3) | Phosphorylation | - | 50.60 | 22912867 | |
| 29 (in isoform 3) | Phosphorylation | - | 3.70 | 28348404 | |
| 43 (in isoform 3) | Phosphorylation | - | 40.45 | 28355574 | |
| 45 | Phosphorylation | RLYLDKATLIWNGNA HHHCCCCEEEECCCC | 25.23 | - | |
| 54 | Phosphorylation | IWNGNAVSGLDALNN EECCCCCCCHHHHHH | 31.09 | - | |
| 73 | Ubiquitination | LPSSEFQVNMLDCQP CCCCCEEEEEECCEE | 5.73 | 22817900 | |
| 78 (in isoform 4) | Ubiquitination | - | 4.30 | 21890473 | |
| 78 | Ubiquitination | FQVNMLDCQPVHEQA EEEEEECCEECCHHC | 4.30 | 21890473 | |
| 100 | Ubiquitination | LVVTSGTVKFDGNKQ EEEECCEEEECCCEE | 7.11 | 22817900 | |
| 101 | Ubiquitination | VVTSGTVKFDGNKQH EEECCEEEECCCEEE | 37.26 | 22817900 | |
| 105 | Ubiquitination | GTVKFDGNKQHFFNQ CEEEECCCEEEEECC | 42.53 | 21890473 | |
| 106 (in isoform 1) | Ubiquitination | - | 51.16 | 21890473 | |
| 106 | Ubiquitination | TVKFDGNKQHFFNQN EEEECCCEEEEECCE | 51.16 | 21890473 | |
| 152 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 156 | Ubiquitination | --------------------- --------------------- | 22817900 | ||
| 161 | Ubiquitination | -------------------------- -------------------------- | 21890473 | ||
| 161 (in isoform 3) | Ubiquitination | - | 21890473 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NXT2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NXT2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NXT2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| NXF3_HUMAN | NXF3 | physical | 16189514 | |
| A4_HUMAN | APP | physical | 21832049 | |
| NXF3_HUMAN | NXF3 | physical | 25416956 | |
| C102B_HUMAN | CCDC102B | physical | 25416956 | |
| CEP63_HUMAN | CEP63 | physical | 25416956 | |
| LNX1_HUMAN | LNX1 | physical | 25416956 | |
| UBP54_HUMAN | USP54 | physical | 25416956 | |
| NXF3_HUMAN | NXF3 | physical | 21516116 | |
| INP4A_HUMAN | INPP4A | physical | 28514442 | |
| NXF1_HUMAN | NXF1 | physical | 28514442 | |
| PTAR1_HUMAN | PTAR1 | physical | 28514442 | |
| RGS8_HUMAN | RGS8 | physical | 28514442 | |
| PTN11_HUMAN | PTPN11 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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