dbPTM

RGPD5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RGPD5_HUMAN
UniProt AC	Q99666
Protein Name	RANBP2-like and GRIP domain-containing protein 5/6
Gene Name	RGPD5
Organism	Homo sapiens (Human).
Sequence Length	1765
Subcellular Localization	Cytoplasm .
Protein Description
Protein Sequence	MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDPKAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKRLKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWQATNTDLLLAYANLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLLSLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLIHRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYIGRSVHYWKKVLPLLKIIKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDAVNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLIKIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRHRWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAILEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSESVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELSKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	DVERYVASVLGLTPS HHHHHHHHHHCCCCC	14.08	28176443
19	Phosphorylation	VASVLGLTPSPRQKS HHHHHCCCCCCCCHH	21.66	30266825
21	Phosphorylation	SVLGLTPSPRQKSMK HHHCCCCCCCCHHHC	27.72	30266825
26	Phosphorylation	TPSPRQKSMKGFYFA CCCCCCHHHCCHHHH	19.86	-
28	Ubiquitination	SPRQKSMKGFYFAKL CCCCHHHCCHHHHHH	53.62	-
34	Ubiquitination	MKGFYFAKLYYEAKE HCCHHHHHHHHHHHH	27.42	21906983
34	Ubiquitination	MKGFYFAKLYYEAKE HCCHHHHHHHHHHHH	27.42	21906983
36	Phosphorylation	GFYFAKLYYEAKEYD CHHHHHHHHHHHHHH	9.88	18083107
37	Phosphorylation	FYFAKLYYEAKEYDL HHHHHHHHHHHHHHH	21.61	-
40	Ubiquitination	AKLYYEAKEYDLAKK HHHHHHHHHHHHHHH	44.88	21906983
40	Ubiquitination	AKLYYEAKEYDLAKK HHHHHHHHHHHHHHH	44.88	21906983
42	Phosphorylation	LYYEAKEYDLAKKYI HHHHHHHHHHHHHHE	18.62	22817900
70	Phosphorylation	HRFLGLLYELEENTE HHHHHHHHHHHHHHH	24.42	-
86	Phosphorylation	AVECYRRSVELNPTQ HHHHHHHHCCCCCCH	15.79	30108239
92	Phosphorylation	RSVELNPTQKDLVLK HHCCCCCCHHHHHHH	47.37	22210691
94	Ubiquitination	VELNPTQKDLVLKIA CCCCCCHHHHHHHHH	56.35	21906983
94	Ubiquitination	VELNPTQKDLVLKIA CCCCCCHHHHHHHHH	56.35	21906983
99	Ubiquitination	TQKDLVLKIAELLCK CHHHHHHHHHHHHHH	32.18	-
106	Ubiquitination	KIAELLCKNDVTDGR HHHHHHHHCCCCCCC	57.03	-
115	Ubiquitination	DVTDGRAKYWVERAA CCCCCCHHHHHHHHH	37.98	-
123	Acetylation	YWVERAAKLFPGSPA HHHHHHHHHCCCCHH	50.07	164319
123	Ubiquitination	YWVERAAKLFPGSPA HHHHHHHHHCCCCHH	50.07	-
128	Phosphorylation	AAKLFPGSPAIYKLK HHHHCCCCHHHHHHH	16.05	30266825
132	Phosphorylation	FPGSPAIYKLKEQLL CCCCHHHHHHHHHHH	16.63	28450419
133	Ubiquitination	PGSPAIYKLKEQLLD CCCHHHHHHHHHHHC	47.14	-
135	Ubiquitination	SPAIYKLKEQLLDCE CHHHHHHHHHHHCCC	38.98	-
177	Phosphorylation	RLVELYRSTKRLKDA EHHHHHHHCHHHHHH	25.40	20860994
178	Phosphorylation	LVELYRSTKRLKDAV HHHHHHHCHHHHHHH	15.93	20860994
182	Ubiquitination	YRSTKRLKDAVAHCH HHHCHHHHHHHHHHH	47.91	-
199	Phosphorylation	ERNIALRSSLEWNSC HHCHHHHHHCHHHHH	39.87	-
200	Phosphorylation	RNIALRSSLEWNSCV HCHHHHHHCHHHHHH	24.71	-
205	Phosphorylation	RSSLEWNSCVVQTLK HHHCHHHHHHHHHHH	14.90	-
248	Phosphorylation	NLMLLTLSTRDVQEN HHHHHHCHHHCHHHH	19.03	24719451
261	Phosphorylation	ENRELLESFDSALQS HHHHHHHHHHHHHHH	34.03	-
264	Phosphorylation	ELLESFDSALQSAKS HHHHHHHHHHHHHHH	28.94	-
280	Phosphorylation	LGGNDELSATFLEMK CCCCCHHHHHHHHCC	24.18	20860994
314	Phosphorylation	NVQWRALSELAALCY HHHHHHHHHHHHHHH	29.58	-
353	Phosphorylation	MMACDRLSQSGHMLL HHHHCHHHHHCCHHH	24.16	-
361	Phosphorylation	QSGHMLLSLSRGKQD HHCCHHHHCCCCCHH	21.97	24719451
363	Phosphorylation	GHMLLSLSRGKQDFL CCHHHHCCCCCHHHH	35.29	22817900
366	Ubiquitination	LLSLSRGKQDFLKEV HHHCCCCCHHHHHHH	45.65	-
380	Ubiquitination	VVETFANKIGQSALY HHHHHHHHHCHHHHH	44.79	21906983
380	Ubiquitination	VVETFANKIGQSALY HHHHHHHHHCHHHHH	44.79	21906983
387	Phosphorylation	KIGQSALYDALFSSQ HHCHHHHHHHHHCCC	10.01	30576142
392	Phosphorylation	ALYDALFSSQSPKDT HHHHHHHCCCCCCCC	28.46	30576142
393	Phosphorylation	LYDALFSSQSPKDTS HHHHHHCCCCCCCCC	27.61	22199227
395	Phosphorylation	DALFSSQSPKDTSFL HHHHCCCCCCCCCCC	35.55	30576142
399	Phosphorylation	SSQSPKDTSFLGSDD CCCCCCCCCCCCCCC	27.75	-
400	Phosphorylation	SQSPKDTSFLGSDDI CCCCCCCCCCCCCCC	28.71	-
409	Ubiquitination	LGSDDIGKIDVQEPE CCCCCCCCCCCCCCC	35.75	21906983
409	Ubiquitination	LGSDDIGKIDVQEPE CCCCCCCCCCCCCCC	35.75	21906983
586	Phosphorylation	WAKYLQKTGSGLNSF HHHHHHHHCCCHHHH	24.50	24719451
592	Phosphorylation	KTGSGLNSFYGQLEY HHCCCHHHHHHHHHH	25.53	24719451
599	Phosphorylation	SFYGQLEYIGRSVHY HHHHHHHHHHCCHHH	19.78	-
606	Phosphorylation	YIGRSVHYWKKVLPL HHHCCHHHHHHHHHH	19.44	24719451
608	Ubiquitination	GRSVHYWKKVLPLLK HCCHHHHHHHHHHHH	26.32	-
609	Ubiquitination	RSVHYWKKVLPLLKI CCHHHHHHHHHHHHH	34.55	-
615	Ubiquitination	KKVLPLLKIIKKNSI HHHHHHHHHHHHCCC	50.50	-
619	Ubiquitination	PLLKIIKKNSIPEPI HHHHHHHHCCCCCCC	45.58	-
680	Phosphorylation	SIKSVVSYWNLALIF HHHHHHHHHHHHHHH	6.16	24260401
700	Phosphorylation	DIENDALSPEEQEEC HHCCCCCCHHHHHHH	31.80	28985074
733	Ubiquitination	DSNLSVVKKLPVPLE CCCCCHHEECCCCHH	46.57	21906983
733	Ubiquitination	DSNLSVVKKLPVPLE CCCCCHHEECCCCHH	46.57	21906983
741	Phosphorylation	KLPVPLESVKQMLNS ECCCCHHHHHHHHHH	42.15	22210691
756	Phosphorylation	VMQELEDYSEGGPLY HHHHHHHHHCCCCCC	10.15	22210691
757	Phosphorylation	MQELEDYSEGGPLYK HHHHHHHHCCCCCCC	41.93	22210691
763	Phosphorylation	YSEGGPLYKNGSLRN HHCCCCCCCCCCCCC	12.92	30387612
764	Ubiquitination	SEGGPLYKNGSLRNA HCCCCCCCCCCCCCC	63.62	-
767	Phosphorylation	GPLYKNGSLRNADSE CCCCCCCCCCCCCCC	33.28	28450419
773	Phosphorylation	GSLRNADSEIKHSTP CCCCCCCCCCCCCCC	38.52	22777824
778	Phosphorylation	ADSEIKHSTPSPTKY CCCCCCCCCCCCCCC	36.69	23663014
779	Phosphorylation	DSEIKHSTPSPTKYS CCCCCCCCCCCCCCC	27.75	23663014
781	Phosphorylation	EIKHSTPSPTKYSLS CCCCCCCCCCCCCCC	45.34	26055452
783	Phosphorylation	KHSTPSPTKYSLSPS CCCCCCCCCCCCCCC	47.13	23663014
784	Ubiquitination	HSTPSPTKYSLSPSK CCCCCCCCCCCCCCC	35.90	-
785	Phosphorylation	STPSPTKYSLSPSKS CCCCCCCCCCCCCCC	19.81	23927012
786	Phosphorylation	TPSPTKYSLSPSKSY CCCCCCCCCCCCCCC	24.75	30266825
788	Phosphorylation	SPTKYSLSPSKSYKY CCCCCCCCCCCCCCC	22.61	22167270
790	Phosphorylation	TKYSLSPSKSYKYSP CCCCCCCCCCCCCCC	30.75	30266825
791	Ubiquitination	KYSLSPSKSYKYSPE CCCCCCCCCCCCCCC	62.28	-
792	Phosphorylation	YSLSPSKSYKYSPET CCCCCCCCCCCCCCC	31.06	23927012
793	Phosphorylation	SLSPSKSYKYSPETP CCCCCCCCCCCCCCC	20.06	23927012
794	Ubiquitination	LSPSKSYKYSPETPP CCCCCCCCCCCCCCC	46.47	-
795	Phosphorylation	SPSKSYKYSPETPPR CCCCCCCCCCCCCCC	22.64	23663014
796	Phosphorylation	PSKSYKYSPETPPRW CCCCCCCCCCCCCCC	16.47	30266825
799	Phosphorylation	SYKYSPETPPRWTED CCCCCCCCCCCCCCC	41.81	23663014
804	Phosphorylation	PETPPRWTEDRNSLL CCCCCCCCCCHHHHH	29.32	28985074
823	Ubiquitination	QQVEAIKKEMQELKL HHHHHHHHHHHHHHC	52.91	-
890	Dimethylation	YNSQYLLRPAANVTP CCCCEEEEECCCCCC	19.06	-
890	Methylation	YNSQYLLRPAANVTP CCCCEEEEECCCCCC	19.06	61996669
896	Phosphorylation	LRPAANVTPTKGSSN EEECCCCCCCCCCCC	25.66	23401153
898	Phosphorylation	PAANVTPTKGSSNTE ECCCCCCCCCCCCCC	38.38	20068231
899	Ubiquitination	AANVTPTKGSSNTEF CCCCCCCCCCCCCCC	58.98	-
901	Phosphorylation	NVTPTKGSSNTEFKS CCCCCCCCCCCCCEE	23.21	26074081
902	Phosphorylation	VTPTKGSSNTEFKST CCCCCCCCCCCCEEC	57.34	26074081
904	Phosphorylation	PTKGSSNTEFKSTKE CCCCCCCCCCEECCC	44.75	26074081
910	Ubiquitination	NTEFKSTKEGFSIPV CCCCEECCCCCEEEE	64.03	-
914	Phosphorylation	KSTKEGFSIPVSADG EECCCCCEEEECCCC	36.52	30266825
918	O-linked_Glycosylation	EGFSIPVSADGFKFG CCCEEEECCCCEECC	18.45	30620550
918	Phosphorylation	EGFSIPVSADGFKFG CCCEEEECCCCEECC	18.45	30266825
923	Ubiquitination	PVSADGFKFGISEPG EECCCCEECCCCCCC	48.48	-
927	Phosphorylation	DGFKFGISEPGNQEK CCEECCCCCCCCCHH	37.81	29978859
934	Ubiquitination	SEPGNQEKKREKPLE CCCCCCHHCCCCCCC	47.57	-
938	Ubiquitination	NQEKKREKPLENDTG CCHHCCCCCCCCCCC	59.96	21906983
952	Phosphorylation	GFQAQDISGRKKGRG CCCCCCCCCCCCCCE	40.61	21712546
966	Phosphorylation	GVIFGQTSSTFTFAD EEEEECCCCCEEHHH	21.35	25693802
967	Phosphorylation	VIFGQTSSTFTFADV EEEECCCCCEEHHHH	30.81	25693802
968	Phosphorylation	IFGQTSSTFTFADVA EEECCCCCEEHHHHH	26.85	25693802
970	Phosphorylation	GQTSSTFTFADVAKS ECCCCCEEHHHHHHH	20.29	25693802
977	Phosphorylation	TFADVAKSTSGEGFQ EHHHHHHHCCCCCCC	20.33	19691289
978	Phosphorylation	FADVAKSTSGEGFQF HHHHHHHCCCCCCCC	39.79	25159151
979	Phosphorylation	ADVAKSTSGEGFQFG HHHHHHCCCCCCCCC	41.77	25159151
987	Ubiquitination	GEGFQFGKKDLNFKG CCCCCCCCCCCCCCC	44.39	-
993	Methylation	GKKDLNFKGFSGAGE CCCCCCCCCCCCCCH	58.95	-
993	Ubiquitination	GKKDLNFKGFSGAGE CCCCCCCCCCCCCCH	58.95	-
996	Phosphorylation	DLNFKGFSGAGEKLF CCCCCCCCCCCHHHH	36.08	28348404
1007	Phosphorylation	EKLFSSRYGKMANKA HHHHHHHHHHHCCCC	24.05	22210691
1016	Phosphorylation	KMANKANTSGDFEKD HHCCCCCCCCCCCCC	38.66	23927012
1017	Phosphorylation	MANKANTSGDFEKDD HCCCCCCCCCCCCCC	35.85	25159151
1027	Phosphorylation	FEKDDDAYKTEDSDD CCCCCCCCCCCCCCC	25.99	25159151
1029	Phosphorylation	KDDDAYKTEDSDDIH CCCCCCCCCCCCCCC	32.14	26503892
1032	Phosphorylation	DAYKTEDSDDIHFEP CCCCCCCCCCCCCEE	30.83	26503892
1046	Ubiquitination	PVVQMPEKVELVTGE ECCCCCCCEEEEECC	34.83	-
1057	Ubiquitination	VTGEEGEKVLYSQGV EECCCCCEEEEECCE	48.69	-
1065	Ubiquitination	VLYSQGVKLFRFDAE EEEECCEEEEEECHH	49.05	-
1085	Ubiquitination	ERGLGNLKILKNEVN HCCCCCCEEHHHHHH	50.41	21890473
1085	Ubiquitination	ERGLGNLKILKNEVN HCCCCCCEEHHHHHH	50.41	21890473
1094	Ubiquitination	LKNEVNGKLRMLMRR HHHHHHHHHHHHHHH	27.93	-
1120	Ubiquitination	ITTTMNLKPLSGSDR EEEEECCEECCCCCC	38.62	-
1127	Methylation	KPLSGSDRAWMWSAS EECCCCCCEEEEEHH	31.67	-
1142	Ubiquitination	DFSDGDAKLERLAAK HCCCCCHHHHHHHHH	56.47	-
1151	Ubiquitination	ERLAAKFKTPELAEE HHHHHHHCCHHHHHH	63.56	-
1152	Phosphorylation	RLAAKFKTPELAEEF HHHHHHCCHHHHHHH	25.73	18669648
1160	Ubiquitination	PELAEEFKQKFEECQ HHHHHHHHHHHHHHH	56.72	21906983
1162	Ubiquitination	LAEEFKQKFEECQRL HHHHHHHHHHHHHHH	56.16	-
1177	Phosphorylation	LLDIPLQTPHKLVDT HHCCCCCCCCCCCHH	34.73	29255136
1180	Ubiquitination	IPLQTPHKLVDTGRA CCCCCCCCCCHHHHH	51.95	-
1184	Phosphorylation	TPHKLVDTGRAAKLI CCCCCCHHHHHHHHH	22.53	26055452
1189	Ubiquitination	VDTGRAAKLIQRAEE CHHHHHHHHHHHHHH	45.17	-
1198	Ubiquitination	IQRAEEMKSGLKDFK HHHHHHHHHCCHHHH	44.65	-
1199	Phosphorylation	QRAEEMKSGLKDFKT HHHHHHHHCCHHHHH	48.31	23401153
1202	Ubiquitination	EEMKSGLKDFKTFLT HHHHHCCHHHHHHHH	65.72	-
1205	Ubiquitination	KSGLKDFKTFLTNDQ HHCCHHHHHHHHCCC	48.80	21890473
1205	Sumoylation	KSGLKDFKTFLTNDQ HHCCHHHHHHHHCCC	48.80	-
1205	Sumoylation	KSGLKDFKTFLTNDQ HHCCHHHHHHHHCCC	48.80	-
1205	Ubiquitination	KSGLKDFKTFLTNDQ HHCCHHHHHHHHCCC	48.80	21890473
1206	Phosphorylation	SGLKDFKTFLTNDQT HCCHHHHHHHHCCCC	24.70	26074081
1209	Phosphorylation	KDFKTFLTNDQTKVT HHHHHHHHCCCCCEE	32.34	24719451
1213	Phosphorylation	TFLTNDQTKVTEEEN HHHHCCCCCEECCCC	30.28	24719451
1214	Ubiquitination	FLTNDQTKVTEEENK HHHCCCCCEECCCCC	41.34	21906983
1216	Phosphorylation	TNDQTKVTEEENKGS HCCCCCEECCCCCCC	38.95	24719451
1223	Phosphorylation	TEEENKGSGTGAAGA ECCCCCCCCCCCCCC	34.49	25159151
1231	Phosphorylation	GTGAAGASDTTIKPN CCCCCCCCCCCCCCC	34.27	25627689
1251	Phosphorylation	PTLEWDNYDLREDAL CCCCCCCCCCCHHHC	17.55	22817900
1261	Phosphorylation	REDALDDSVSSSSVH CHHHCCCCCCCCCCC	24.46	30266825
1263	Phosphorylation	DALDDSVSSSSVHAS HHCCCCCCCCCCCCC	28.58	30266825
1264	Phosphorylation	ALDDSVSSSSVHASP HCCCCCCCCCCCCCC	25.20	23401153
1265	Phosphorylation	LDDSVSSSSVHASPL CCCCCCCCCCCCCCC	28.95	25463755
1266	Phosphorylation	DDSVSSSSVHASPLA CCCCCCCCCCCCCCC	21.62	23401153
1270	Phosphorylation	SSSSVHASPLASSPV CCCCCCCCCCCCCCC	12.93	29255136
1274	Phosphorylation	VHASPLASSPVRKNL CCCCCCCCCCCCCCE	42.74	29255136
1275	Phosphorylation	HASPLASSPVRKNLF CCCCCCCCCCCCCEE	23.08	29255136
1287	Phosphorylation	NLFRFDESTTGSNFS CEECCCCCCCCCCCC	32.87	30266825
1288	Phosphorylation	LFRFDESTTGSNFSF EECCCCCCCCCCCCH	32.88	30266825
1289	Phosphorylation	FRFDESTTGSNFSFK ECCCCCCCCCCCCHH	48.14	30266825
1291	Phosphorylation	FDESTTGSNFSFKSA CCCCCCCCCCCHHHH	32.39	30266825
1294	Phosphorylation	STTGSNFSFKSALSL CCCCCCCCHHHHHHH	35.69	30266825
1300	Phosphorylation	FSFKSALSLSKSPAK CCHHHHHHHCCCCCC	30.25	26074081
1302	Phosphorylation	FKSALSLSKSPAKLN HHHHHHHCCCCCCCC	27.93	26055452
1303	Ubiquitination	KSALSLSKSPAKLNQ HHHHHHCCCCCCCCC	66.79	-
1304	Phosphorylation	SALSLSKSPAKLNQS HHHHHCCCCCCCCCC	27.06	26055452
1311	Phosphorylation	SPAKLNQSGTSVGTD CCCCCCCCCCCCCCC	42.86	23663014
1313	Phosphorylation	AKLNQSGTSVGTDEE CCCCCCCCCCCCCCC	26.03	28985074
1314	Phosphorylation	KLNQSGTSVGTDEES CCCCCCCCCCCCCCC	23.29	22496350
1317	Phosphorylation	QSGTSVGTDEESVVT CCCCCCCCCCCCCCC	37.77	21130716
1321	Phosphorylation	SVGTDEESVVTQEEE CCCCCCCCCCCCCHH	21.60	26471730
1324	Phosphorylation	TDEESVVTQEEERDG CCCCCCCCCCHHHCC	28.27	26471730
1333	Phosphorylation	EEERDGQYFEPVVPL CHHHCCCCCCCCEEC	18.55	-
1368	Ubiquitination	AEIYRYDKDVGQWKE EEEEEECCCCCCHHH	45.43	-
1374	Ubiquitination	DKDVGQWKERGIGDI CCCCCCHHHCCCCCE	29.64	-
1382	Ubiquitination	ERGIGDIKILQNYDN HCCCCCEEEEECCCC	41.95	21890473
1382	Ubiquitination	ERGIGDIKILQNYDN HCCCCCEEEEECCCC	41.95	21890473
1387	Phosphorylation	DIKILQNYDNKQVRI CEEEEECCCCCCEEE	14.13	28152594
1390	Ubiquitination	ILQNYDNKQVRIVMR EEECCCCCCEEEEEE	47.47	-
1403	Ubiquitination	MRRDQVLKLCANHRI EEHHHHHHHHHCCCC	42.54	21906983
1411	Phosphorylation	LCANHRITPDMSLQN HHHCCCCCCCCCHHC	17.13	-
1415	Phosphorylation	HRITPDMSLQNMKGT CCCCCCCCHHCCCCC	33.90	23186163
1420	Ubiquitination	DMSLQNMKGTERVWV CCCHHCCCCCCEEEE	70.95	2190698
1422	Phosphorylation	SLQNMKGTERVWVWT CHHCCCCCCEEEEEE	18.33	-
1439	Acetylation	DFADGERKVEHLAVR CCCCCCCHHEEEHHH	47.90	30591895
1448	Ubiquitination	EHLAVRFKLQDVADS EEEHHHHHHHHHHHH	34.37	21890473
1448	Sumoylation	EHLAVRFKLQDVADS EEEHHHHHHHHHHHH	34.37	-
1448	Sumoylation	EHLAVRFKLQDVADS EEEHHHHHHHHHHHH	34.37	-
1448	Ubiquitination	EHLAVRFKLQDVADS EEEHHHHHHHHHHHH	34.37	21890473
1455	Phosphorylation	KLQDVADSFKKIFDE HHHHHHHHHHHHHHH	29.27	20068231
1458	Ubiquitination	DVADSFKKIFDEAKT HHHHHHHHHHHHHHH	46.74	-
1464	Ubiquitination	KKIFDEAKTAQEKDS HHHHHHHHHHHHHHC	42.20	-
1465	Phosphorylation	KIFDEAKTAQEKDSL HHHHHHHHHHHHHCC	40.39	23927012
1469	Ubiquitination	EAKTAQEKDSLITPH HHHHHHHHHCCCCCC	40.30	-
1471	Phosphorylation	KTAQEKDSLITPHVS HHHHHHHCCCCCCCC	32.51	30266825
1474	Phosphorylation	QEKDSLITPHVSRSS HHHHCCCCCCCCCCC	16.79	29255136
1478	Phosphorylation	SLITPHVSRSSTPRE CCCCCCCCCCCCCCC	24.34	29255136
1480	Phosphorylation	ITPHVSRSSTPRESP CCCCCCCCCCCCCCC	30.93	26055452
1481	Phosphorylation	TPHVSRSSTPRESPC CCCCCCCCCCCCCCC	41.12	26055452
1482	Phosphorylation	PHVSRSSTPRESPCG CCCCCCCCCCCCCCH	27.84	23401153
1486	Phosphorylation	RSSTPRESPCGKIAV CCCCCCCCCCHHHHH	27.11	23401153
1504	Phosphorylation	EETTRERTDVIQGDD HHHCCCCCCCCCCCC	29.84	22210691
1517	Phosphorylation	DDVADAASEVEVSST CCHHHHHCEEEECCC	43.85	20068231
1522	Phosphorylation	AASEVEVSSTSETTT HHCEEEECCCCCCCC	17.88	22817900
1523	Phosphorylation	ASEVEVSSTSETTTK HCEEEECCCCCCCCC	40.92	22817900
1524	Phosphorylation	SEVEVSSTSETTTKA CEEEECCCCCCCCCE	24.07	20068231
1525	Phosphorylation	EVEVSSTSETTTKAV EEEECCCCCCCCCEE	34.59	20068231
1527	Phosphorylation	EVSSTSETTTKAVVS EECCCCCCCCCEEEC	39.26	20068231
1528	Phosphorylation	VSSTSETTTKAVVSP ECCCCCCCCCEEECC	23.42	20068231
1529	Phosphorylation	SSTSETTTKAVVSPP CCCCCCCCCEEECCC	25.15	20068231
1534	Phosphorylation	TTTKAVVSPPKFVFV CCCCEEECCCEEEEE	28.96	23401153
1544	Phosphorylation	KFVFVSESVKRIFSS EEEEEEHHHHHHHCC	25.98	27050516
1550	Phosphorylation	ESVKRIFSSEKSKPF HHHHHHHCCCCCCCE	34.90	24719451
1551	Phosphorylation	SVKRIFSSEKSKPFV HHHHHHCCCCCCCEE	37.99	21857030
1553	Ubiquitination	KRIFSSEKSKPFVFG HHHHCCCCCCCEEEC	66.77	21906983
1555	Ubiquitination	IFSSEKSKPFVFGNS HHCCCCCCCEEECCC	54.25	21906983
1565	Phosphorylation	VFGNSSATGSLFGFS EECCCCCCCCCCEEE	29.29	24719451
1567	Phosphorylation	GNSSATGSLFGFSFN CCCCCCCCCCEEEEE	19.03	24719451
1572	Phosphorylation	TGSLFGFSFNAPLKS CCCCCEEEEECCCCC	20.26	24719451
1578	Sumoylation	FSFNAPLKSNNSETS EEEECCCCCCCCCCC	50.51	-
1579	Phosphorylation	SFNAPLKSNNSETSS EEECCCCCCCCCCCC	49.26	29396449
1582	Phosphorylation	APLKSNNSETSSVAQ CCCCCCCCCCCCCCC	46.64	30576142
1584	Phosphorylation	LKSNNSETSSVAQSG CCCCCCCCCCCCCCC	26.56	23663014
1585	Phosphorylation	KSNNSETSSVAQSGS CCCCCCCCCCCCCCC	20.82	23663014
1586	Phosphorylation	SNNSETSSVAQSGSE CCCCCCCCCCCCCCC	28.97	23663014
1590	Phosphorylation	ETSSVAQSGSESKVE CCCCCCCCCCCCCCC	34.25	25262027
1592	Phosphorylation	SSVAQSGSESKVEPK CCCCCCCCCCCCCCC	43.90	25262027
1594	Phosphorylation	VAQSGSESKVEPKKC CCCCCCCCCCCCCCC	43.64	23663014
1595	Sumoylation	AQSGSESKVEPKKCE CCCCCCCCCCCCCCC	46.71	-
1595	Sumoylation	AQSGSESKVEPKKCE CCCCCCCCCCCCCCC	46.71	-
1595	Ubiquitination	AQSGSESKVEPKKCE CCCCCCCCCCCCCCC	46.71	21906983
1604	Phosphorylation	EPKKCELSKNSDIEQ CCCCCCCCCCCCCCC	13.90	23663014
1605	Ubiquitination	PKKCELSKNSDIEQS CCCCCCCCCCCCCCC	73.44	-
1607	Phosphorylation	KCELSKNSDIEQSSD CCCCCCCCCCCCCCC	43.64	21712546
1612	Phosphorylation	KNSDIEQSSDSKVKN CCCCCCCCCCHHCEE	24.27	26425664
1613	Phosphorylation	NSDIEQSSDSKVKNL CCCCCCCCCHHCEEE	45.67	26055452
1615	Phosphorylation	DIEQSSDSKVKNLSA CCCCCCCHHCEEEEE	41.10	21406692
1616	Sumoylation	IEQSSDSKVKNLSAS CCCCCCHHCEEEEEC	63.32	-
1616	Sumoylation	IEQSSDSKVKNLSAS CCCCCCHHCEEEEEC	63.32	-
1618	Ubiquitination	QSSDSKVKNLSASFP CCCCHHCEEEEECCC	56.77	-
1621	Phosphorylation	DSKVKNLSASFPTEE CHHCEEEEECCCCCC	31.12	25159151
1623	Phosphorylation	KVKNLSASFPTEESS HCEEEEECCCCCCCC	28.51	26471730
1626	Phosphorylation	NLSASFPTEESSINY EEEECCCCCCCCCEE	50.83	26471730
1629	Phosphorylation	ASFPTEESSINYTFK ECCCCCCCCCEEEEC	30.22	23663014
1630	Phosphorylation	SFPTEESSINYTFKT CCCCCCCCCEEEECC	20.38	23663014
1633	Phosphorylation	TEESSINYTFKTPEK CCCCCCEEEECCCCC	16.34	18691976
1634	Phosphorylation	EESSINYTFKTPEKE CCCCCEEEECCCCCC	17.73	26074081
1637	Phosphorylation	SINYTFKTPEKEPPL CCEEEECCCCCCCCC	32.27	25159151
1640	Ubiquitination	YTFKTPEKEPPLWHA EEECCCCCCCCCEEE	76.39	-
1651	Ubiquitination	LWHAEFTKEELVQKL CEEEECCHHHHHHHH	55.29	-
1657	Ubiquitination	TKEELVQKLRSTTKS CHHHHHHHHHHHCCC	38.09	-
1660	Phosphorylation	ELVQKLRSTTKSADH HHHHHHHHHCCCHHH	51.36	-
1661	Phosphorylation	LVQKLRSTTKSADHL HHHHHHHHCCCHHHH	31.63	-
1663	Ubiquitination	QKLRSTTKSADHLNG HHHHHHCCCHHHHHH	43.67	-
1664	Phosphorylation	KLRSTTKSADHLNGL HHHHHCCCHHHHHHH	36.52	25159151
1690	Ubiquitination	MEQIKLLKSEIRRLE HHHHHHHHHHHHHHH	57.38	-
1704	Ubiquitination	ERNQEREKSAANLEY HHHHHHHHHHHHHHH	52.17	-
1705	Phosphorylation	RNQEREKSAANLEYL HHHHHHHHHHHHHHH	28.06	-
1711	Phosphorylation	KSAANLEYLKNVLLQ HHHHHHHHHHHHHHH	26.58	22817900
1723	Ubiquitination	LLQFIFLKPGSERER HHHHHHCCCCCHHHH	36.26	-
1737	Phosphorylation	RLLPVINTMLQLSPE HHHHHHHHHHHCCHH	14.24	27251275
1742	Phosphorylation	INTMLQLSPEEKGKL HHHHHHCCHHHCCHH	19.80	22617229
1748	Ubiquitination	LSPEEKGKLAAVAQD CCHHHCCHHEEECCC	46.12	21906983
1761	Phosphorylation	QDEEENASRSSG--- CCHHHHHHHCCC---	44.25	23663014
1763	Phosphorylation	EEENASRSSG----- HHHHHHHCCC-----	36.60	23663014
1764	Phosphorylation	EENASRSSG------ HHHHHHCCC------	47.62	23663014

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
1275	S	Phosphorylation	Kinase	CDK1	P06493	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RGPD5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RGPD5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TNPO1_HUMAN	TNPO1	physical	12905863
AF10_MOUSE	Mllt10	physical	11774384
TNPO1_MOUSE	Tnpo1	physical	11774384

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RGPD5_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-979; SER-1270; SER-1275;SER-1478 AND THR-1584, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-19; SER-21 AND SER-788,AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND MASSSPECTROMETRY.	18220336 [Abstract]
"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."; Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.; J. Proteome Res. 6:4150-4162(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1177, AND MASSSPECTROMETRY.	17924679 [Abstract]