CRC1_YEAST - dbPTM
CRC1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CRC1_YEAST
UniProt AC Q12289
Protein Name Mitochondrial carnitine carrier
Gene Name CRC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 327
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description Transports carnitine, acetylcarnitine, propionylcarnitine and to a much lower extent medium- and long-chain acylcarnitines..
Protein Sequence MSSDTSLSESSLLKEESGSLTKSRPPIKSNPVRENIKSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVKGFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAGFISAIPTTLVTAPTERVKVVLQTSSKGSFIQAAKTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQNMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEMTHSLFKKYGI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
38PhosphorylationPVRENIKSFVAGGVG
CCHHHHHHHHCCCCC		22.5827214570
171PhosphorylationRVKVVLQTSSKGSFI
EEEEEEECCCCCHHH		30.7027214570
173PhosphorylationKVVLQTSSKGSFIQA
EEEEECCCCCHHHHH		44.4127214570
270PhosphorylationIKTKLQASSTRQNML
HHHHHHCCHHHHHHH		21.2026447709
271PhosphorylationKTKLQASSTRQNMLS
HHHHHCCHHHHHHHH		30.5326447709
272PhosphorylationTKLQASSTRQNMLSA
HHHHCCHHHHHHHHH		33.5026447709
278PhosphorylationSTRQNMLSATKEIYL
HHHHHHHHHHHHHHH		24.1126447709
280PhosphorylationRQNMLSATKEIYLQR
HHHHHHHHHHHHHHC		26.3226447709
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CRC1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CRC1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CRC1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ERR1_YEASTERR1physical
18467557
ERR2_YEASTERR1physical
18467557
HFA1_YEASTHFA1genetic
21623372
RMD9L_YEASTYBR238Cgenetic
27708008
IMG2_YEASTIMG2genetic
27708008
MIC19_YEASTMIC19genetic
27708008
RCY1_YEASTRCY1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
TSA1_YEASTTSA1genetic
27708008
GBLP_YEASTASC1genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
KMO_YEASTBNA4genetic
27708008
YB75_YEASTYBR225Wgenetic
27708008
SNF5_YEASTSNF5genetic
27708008
RER1_YEASTRER1genetic
27708008
YCA2_YEASTYCL002Cgenetic
27708008
GFD2_YEASTGFD2genetic
27708008
ATG22_YEASTATG22genetic
27708008
ELO2_YEASTELO2genetic
27708008
RL13A_YEASTRPL13Agenetic
27708008
ATG9_YEASTATG9genetic
27708008
ACL4_YEASTYDR161Wgenetic
27708008
LSM6_YEASTLSM6genetic
27708008
FIT1_YEASTFIT1genetic
27708008
DDI1_YEASTDDI1genetic
27708008
YFH6_YEASTYFR006Wgenetic
27708008
ATG18_YEASTATG18genetic
27708008
PALF_YEASTRIM8genetic
27708008
SGF73_YEASTSGF73genetic
27708008
COM1_YEASTSAE2genetic
27708008
ATG1_YEASTATG1genetic
27708008
MDM34_YEASTMDM34genetic
27708008
CUL3_YEASTCUL3genetic
27708008
RME1_YEASTRME1genetic
27708008
MPC3_YEASTMPC3genetic
27708008
TNA1_YEASTTNA1genetic
27708008
LRP1_YEASTLRP1genetic
27708008
YHT1_YEASTYHR131Cgenetic
27708008
ALLA_YEASTDAL3genetic
27708008
SDHX_YEASTYJL045Wgenetic
27708008
LPLA_YEASTAIM22genetic
27708008
YJ09_YEASTYJR039Wgenetic
27708008
DHOM_YEASTHOM6genetic
27708008
POC3_YEASTIRC25genetic
27708008
SWI6_YEASTSWI6genetic
27708008
YL278_YEASTYLR278Cgenetic
27708008
OGG1_YEASTOGG1genetic
27708008
VPS9_YEASTVPS9genetic
27708008
YM8V_YEASTYMR295Cgenetic
27708008
DIA1_YEASTDIA1genetic
27708008
YND5_YEASTYNL035Cgenetic
27708008
YPT53_YEASTYPT53genetic
27708008
NTH2_YEASTNTG2genetic
27708008
PSK2_YEASTPSK2genetic
27708008
FUMH_YEASTFUM1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
MMS1_YEASTMMS1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CRC1_YEAST

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Related Literatures of Post-Translational Modification

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