YPS6_YEAST - dbPTM
YPS6_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YPS6_YEAST
UniProt AC P40583
Protein Name Aspartic proteinase yapsin-6
Gene Name YPS6
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 537
Subcellular Localization Cell membrane
Lipid-anchor, GPI-anchor .
Protein Description Cleaves proteins C-terminally to mono- and paired-basic residues (By similarity). Required for cell wall integrity..
Protein Sequence MQLISILSLLSSLMCSLTVLGSSASSYVKFPVQKLADIINICTQDVSTVFKRNEVLNTTVINGIGVYVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTATFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVSFENITLNDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKNQGKINKIAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQSVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKVNDTLLSVDFGGFNISANISNFVTSAKDRCVLNVKQSESTYMLGDAFLVDAYVVYDLENYEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSYSEFSQYKSLLATAAQSDDASSFSSSGGSSESTTKKQNAGYKYRSSFSFSLLSFISYFLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
57N-linked_GlycosylationFKRNEVLNTTVINGI
HHHCCCCCEEEECCE		38.59-
149N-linked_GlycosylationWGTFDASNSSTFENN
HCCCCCCCCCCCCCC		41.52-
156N-linked_GlycosylationNSSTFENNATFFNNT
CCCCCCCCCEEECCC		32.91-
161N-linked_GlycosylationENNATFFNNTYGDGT
CCCCEEECCCCCCCE		35.42-
183N-linked_GlycosylationTDVVSFENITLNDFT
CEEEEEECEEECCEE		30.45-
195N-linked_GlycosylationDFTFGVSNDTIGNPS
CEEEECCCCCCCCCC		48.30-
311N-linked_GlycosylationILDSESGNKTVSDIQ
EEECCCCCEEEEEEE		46.21-
363N-linked_GlycosylationIFDCSKVNDTLLSVD
EEEHHHCCCEEEEEE		40.04-
375N-linked_GlycosylationSVDFGGFNISANISN
EEECCCEEEEEEHHH		30.49-
379N-linked_GlycosylationGGFNISANISNFVTS
CCEEEEEEHHHHHCC		31.28-
472N-linked_GlycosylationIGTGDFINVSWTSYS
CCCCCCEEEECCCHH		23.05-
515GPI-anchorESTTKKQNAGYKYRS
CCCCCCCCCCCCCCC		44.18-
522PhosphorylationNAGYKYRSSFSFSLL
CCCCCCCCCHHHHHH		32.4228889911
525PhosphorylationYKYRSSFSFSLLSFI
CCCCCCHHHHHHHHH		18.8428889911
533PhosphorylationFSLLSFISYFLL---
HHHHHHHHHHHC---		14.0728889911
534PhosphorylationSLLSFISYFLL----
HHHHHHHHHHC----		8.0728889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YPS6_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YPS6_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YPS6_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YPS7_YEASTYPS7genetic
16087741
SSB1_YEASTSSB1physical
19536198
RS8A_YEASTRPS8Agenetic
27708008
RS8B_YEASTRPS8Agenetic
27708008
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
PYC2_YEASTPYC2genetic
27708008
RIM15_YEASTRIM15genetic
27708008
OSH1_YEASTSWH1genetic
27708008
ATG8_YEASTATG8genetic
27708008
MNN2_YEASTMNN2genetic
27708008
ETR1_YEASTETR1genetic
27708008
TIP1_YEASTTIP1genetic
27708008
MAL33_YEASTMAL33genetic
27708008
YCR3_YEASTYCR023Cgenetic
27708008
ABP1_YEASTABP1genetic
27708008
YCY0_YEASTYCR090Cgenetic
27708008
YCZ2_YEASTYCR102Cgenetic
27708008
GPR1_YEASTGPR1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
UBX3_YEASTUBX3genetic
27708008
ATG9_YEASTATG9genetic
27708008
YEV1_YEASTYER121Wgenetic
27708008
WWM1_YEASTWWM1genetic
27708008
CSK2B_YEASTCKB1genetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
MON1_YEASTMON1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
YJE9_YEASTYJL049Wgenetic
27708008
YJ24_YEASTKCH1genetic
27708008
YJ90_YEASTYJR120Wgenetic
27708008
KAPC_YEASTTPK3genetic
27708008
LIPB_YEASTLIP2genetic
27708008
YL287_YEASTYLR287Cgenetic
27708008
GLRX8_YEASTGRX8genetic
27708008
SOK2_YEASTSOK2genetic
27708008
UBC7_YEASTUBC7genetic
27708008
YET2_YEASTYET2genetic
27708008
ATG3_YEASTATG3genetic
27708008
MSN1_YEASTMSN1genetic
27708008
TRM11_YEASTTRM11genetic
27708008
KTR1_YEASTKTR1genetic
27708008
MCA1_YEASTMCA1genetic
27708008
KIN4_YEASTKIN4genetic
27708008
RAD1_YEASTRAD1genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
NEW1_YEASTNEW1genetic
27708008
FUMH_YEASTFUM1genetic
27708008
YP022_YEASTYPR022Cgenetic
27708008
SRO7_YEASTSRO7genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YPS6_YEAST

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Related Literatures of Post-Translational Modification

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