UAP2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UAP2_SCHPO
• UniProt AC: O43120
• Protein Name: Splicing factor U2AF-associated protein 2
• Gene Name: uap2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 367
• Protein Description: Has a role in pre-mRNA splicing..
• Protein Sequence: MSSQPFWDERIHRWRCLGSEGNELIYIDEEQTWKDYDPNSLKMNKAGSTGAEVSDVTAEATEGKESSNGEDRHTKRLYESTSAEGYPSGSRNKKSKSENSEASPAPVINKAVYIQGLPLDVTVDEIEEVFKKCGVIAKNIDNGTPRIKIYRTEDGTPKGDALIVFFRSESVELAEQLFDDTEFRYGSGQKMRVQKANIDYKKEKTVNKDVGGALKKKALRLRQQQMQQISSWDDVDEEVDDKRKKRFNKIVVLKHIFTLEELDKTPELLIDLKDDITEEAEKCGRVTNVVLYDKEPDGVVTVRFSNNEEAEACVRLMQGRYFDGRVVEASIYDGKVRFQKSGKHTLDDEEDEEKRLEKFADWLENSN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	LKMNKAGSTGAEVSD CCCCCCCCCCCEECC	28.64	28889911
49	Phosphorylation	KMNKAGSTGAEVSDV CCCCCCCCCCEECCE	39.22	29996109
366	Phosphorylation	FADWLENSN------ HHHHHHCCC------	34.24	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UAP2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UAP2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UAP2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
U2AF2_SCHPO	prp2	physical	9371883
U2AF1_SCHPO	uaf2	physical	9371883
U2AF2_SCHPO	prp2	physical	10923022
U2AF2_SCHPO	prp2	physical	11686295
YBX5_SCHPO	SPBC17D1.05	genetic	22681890
YCRE_SCHPO	trs130	genetic	22681890
IDHP_SCHPO	idp1	genetic	22681890
YOI5_SCHPO	SPBC1778.05c	genetic	22681890
YI81_SCHPO	SPAPJ695.01c	genetic	22681890
RTF2_SCHPO	rtf2	genetic	22681890
FFT2_SCHPO	fft2	genetic	22681890
TRK1_SCHPO	trk1	genetic	22681890
REXO3_SCHPO	rex3	genetic	22681890
YAC5_SCHPO	cph1	genetic	22681890
ATCX_SCHPO	SPAC24B11.12c	genetic	22681890
DEP1_SCHPO	dep1	genetic	22681890
SIF2_SCHPO	sif2	genetic	22681890
VIP1_SCHPO	asp1	genetic	22681890
ARP8_SCHPO	arp8	genetic	22681890
YPS1_SCHPO	yps1	genetic	22681890
RPA12_SCHPO	rpa12	genetic	22681890
YIQ4_SCHPO	SPAC824.04	genetic	22681890
UAF30_SCHPO	spp27	genetic	22681890
SST6_SCHPO	sst6	genetic	22681890
YAJE_SCHPO	SPAC30D11.14c	genetic	22681890
YAQD_SCHPO	SPAC18G6.13	genetic	22681890
PHD1_SCHPO	hos2	genetic	22681890
SET3_SCHPO	set3	genetic	22681890
RRF1_SCHPO	rrf1	genetic	22681890
VPS38_SCHPO	vps38	genetic	22681890
NTO1_SCHPO	nto1	genetic	22681890
ING2_SCHPO	png2	genetic	22681890
YO48_SCHPO	SPBC36B7.08c	genetic	22681890
DSK1_SCHPO	dsk1	genetic	22681890
GNR1_SCHPO	gnr1	genetic	22681890
YCRA_SCHPO	SPCC285.10c	genetic	22681890
POF3_SCHPO	pof3	genetic	22681890
MST2_SCHPO	mst2	genetic	22681890
YIU1_SCHPO	saf5	genetic	22681890
YJ53_SCHPO	SPCC4F11.03c	genetic	22681890
YJKA_SCHPO	SPCC18B5.10c	genetic	22681890
CTK3_SCHPO	lsg1	genetic	22681890
PFL7_SCHPO	pfl7	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
RPB9_SCHPO	rpb9	genetic	22681890
YHZ3_SCHPO	ath1	genetic	22681890
IVN1_SCHPO	ivn1	genetic	22681890
SIF3_SCHPO	sif3	genetic	22681890
SDE2_SCHPO	sde2	genetic	22681890
GEF1_SCHPO	gef1	genetic	22681890
SLD3_SCHPO	sld3	genetic	22681890
PVH1_SCHPO	SPBC17A3.06	genetic	22681890
POZ1_SCHPO	poz1	genetic	22681890
YK42_SCHPO	tos4	genetic	22681890
PRZ1_SCHPO	prz1	genetic	22681890
CSK1_SCHPO	csk1	genetic	22681890
YI43_SCHPO	SPBC1348.03	genetic	22681890
OMH6_SCHPO	omh6	genetic	22681890
PSK1_SCHPO	psk1	genetic	22681890
ULP1_SCHPO	ulp1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.