| UniProt ID | GNR1_SCHPO | |
|---|---|---|
| UniProt AC | O59762 | |
| Protein Name | Guanine nucleotide-binding protein negative regulator 1 | |
| Gene Name | gnr1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 399 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | Negatively regulates the pheromone-response pathway. Acts as a structural mimic of the G protein beta subunit thereby interacting with gpa1 which then inhibits gpa1 signaling.. | |
| Protein Sequence | MDNCVNSFEDQKDDLVHKKKSQNFGYVCGSINLGTNVIAQSPTKPLNFFHSSRWSPDGSTILSLTEDQCLNCWNVPFSDLSKKADGPLNFSKHLSYKYQSPETVYSYSWYSRMKLDDPSSNLFAVSSRDQPIKLINFTTGKNKASYHMIDHQERYQGSHCLQFTNDGEYLIAGDKNCLHHFNIRTGCKEPVMTTVTHGYKVPLWEFSLKGIQSCFSLNPMDSKTLAVGTYSNRVGIYNDCGRRPCQLEFSIERGNGVTHLQWCEDGEKLYVGSRCSDKIEVWDIRYVRDMVYALEGHRGDTNQRILFDTDKKDEILAGGTDGSIRRWRNKDLVEETHVTGNYDLTVNTVQANPINMQIKCVCYGNRIYKYEKDESEEEDESKEKDLWTGTVSALQVWMD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of GNR1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GNR1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GNR1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GNR1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HRR1_SCHPO | hrr1 | genetic | 18818364 | |
| PCK1_SCHPO | pck1 | genetic | 22681890 | |
| RAV2_SCHPO | rav2 | genetic | 22681890 | |
| ADK_SCHPO | ado1 | genetic | 22681890 | |
| YAQD_SCHPO | SPAC18G6.13 | genetic | 22681890 | |
| DSK1_SCHPO | dsk1 | genetic | 22681890 | |
| RAF1_SCHPO | raf1 | genetic | 22681890 | |
| PPK16_SCHPO | ppk16 | genetic | 22681890 | |
| RS4B_SCHPO | rps402 | genetic | 22681890 | |
| YCPE_SCHPO | trp663 | genetic | 22681890 | |
| SPF31_SCHPO | spf31 | genetic | 22681890 | |
| KCC1_SCHPO | cmk1 | genetic | 22681890 | |
| CSK1_SCHPO | csk1 | genetic | 22681890 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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