GFOD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GFOD1_HUMAN
• UniProt AC: Q9NXC2
• Protein Name: Glucose-fructose oxidoreductase domain-containing protein 1
• Gene Name: GFOD1
• Organism: Homo sapiens (Human).
• Sequence Length: 390
• Subcellular Localization: Secreted .
• Protein Sequence: MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMTSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGEPLVCEVQVHGGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLVQDATPVSNSLLPEKAFSDIPSPYLRGTIKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLISEAMRRSRMSLYC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	PGVGVFGTSLTARVI CCCCCCCCCEEEEHH	14.75	30177828
11	Phosphorylation	GVGVFGTSLTARVII CCCCCCCCEEEEHHH	24.89	30177828
13	Phosphorylation	GVFGTSLTARVIIPL CCCCCCEEEEHHHHH	16.51	30177828
47	Phosphorylation	EELAKEMSVPFYTSR HHHHHHCCCCCCCCC	27.94	24719451
158	Ubiquitination	HGGSLLGKKYNWSCD ECCCCCCCEECCCHH	52.64	-
204	Ubiquitination	GLLKTFVKQTDHIKG HHHHHHHHCCCCCCC	43.20	-
288	Phosphorylation	DATPVSNSLLPEKAF CCCCCCCCCCCHHHH	24.63	20860994
356	Phosphorylation	TIKRSSQTGEWQNIA HHHHCCCCCCCEEEE	38.73	-
384	Phosphorylation	ISEAMRRSRMSLYC- HHHHHHHHHHCCCC-	23.21	27251275
387	Phosphorylation	AMRRSRMSLYC---- HHHHHHHCCCC----	18.31	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GFOD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GFOD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GFOD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GFOD1_HUMAN	GFOD1	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
FAM9B_HUMAN	FAM9B	physical	25416956
KR108_HUMAN	KRTAP10-8	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956
NT2NL_HUMAN	NOTCH2NL	physical	25416956
GFOD2_HUMAN	GFOD2	physical	26186194
TBB8_HUMAN	TUBB8	physical	26186194
RPA2_HUMAN	POLR1B	physical	26186194
RGPA1_HUMAN	RALGAPA1	physical	26186194
RGPA2_HUMAN	RALGAPA2	physical	26186194
ESPL1_HUMAN	ESPL1	physical	26186194
RLGPB_HUMAN	RALGAPB	physical	26186194
PLEC_HUMAN	PLEC	physical	26186194
WDR76_HUMAN	WDR76	physical	26186194
BCAT1_HUMAN	BCAT1	physical	26186194
RB6I2_HUMAN	ERC1	physical	26186194
PI51A_HUMAN	PIP5K1A	physical	26186194
SC24A_HUMAN	SEC24A	physical	26186194
CBPC5_HUMAN	AGBL5	physical	26186194
MTMR5_HUMAN	SBF1	physical	26186194
FBX9_HUMAN	FBXO9	physical	26186194
DPOD1_HUMAN	POLD1	physical	26186194
FANCJ_HUMAN	BRIP1	physical	26186194
RPA1_HUMAN	POLR1A	physical	26186194
TSR3_HUMAN	TSR3	physical	26186194
KBRS2_HUMAN	NKIRAS2	physical	26186194
P4K2B_HUMAN	PI4K2B	physical	26186194
NMT2_HUMAN	NMT2	physical	26186194
SPA5L_HUMAN	SPATA5L1	physical	26186194
DPH1_HUMAN	DPH1	physical	26186194
PRI2_HUMAN	PRIM2	physical	26186194
PER1_HUMAN	PER1	physical	26186194
PUSL1_HUMAN	PUSL1	physical	26186194
IF122_HUMAN	IFT122	physical	26186194
CAR10_HUMAN	CARD10	physical	26186194
GILT_HUMAN	IFI30	physical	26186194
GFOD2_HUMAN	GFOD2	physical	28514442
RGPA1_HUMAN	RALGAPA1	physical	28514442
RGPA2_HUMAN	RALGAPA2	physical	28514442
RLGPB_HUMAN	RALGAPB	physical	28514442
CAR10_HUMAN	CARD10	physical	28514442
FBX9_HUMAN	FBXO9	physical	28514442
RB6I2_HUMAN	ERC1	physical	28514442
BCAT1_HUMAN	BCAT1	physical	28514442
CBPC5_HUMAN	AGBL5	physical	28514442
MTMR5_HUMAN	SBF1	physical	28514442
P4K2B_HUMAN	PI4K2B	physical	28514442
PI51A_HUMAN	PIP5K1A	physical	28514442
PLEC_HUMAN	PLEC	physical	28514442
PUSL1_HUMAN	PUSL1	physical	28514442
FANCJ_HUMAN	BRIP1	physical	28514442
PER1_HUMAN	PER1	physical	28514442
ESPL1_HUMAN	ESPL1	physical	28514442
TSR3_HUMAN	TSR3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.