dbPTM

FGL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FGL1_HUMAN
UniProt AC	Q08830
Protein Name	Fibrinogen-like protein 1
Gene Name	FGL1
Organism	Homo sapiens (Human).
Sequence Length	312
Subcellular Localization	Secreted.
Protein Description	Has hepatocyte mitogenic activity..
Protein Sequence	MAKVFSFILVTTALTMGREISALEDCAQEQMRLRAQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFNDGYKLSGFYKIKPLQSPAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MAKVFSFILVTTA --CCHHHHHHHHHHH	17.86	-
154	Phosphorylation	FVQKHGEYWLGNKNL HHHHHCCEECCCCCE	15.55	29083192
165	Phosphorylation	NKNLHFLTTQEDYTL CCCEEEEECCCCEEE	26.03	26074081
166	Phosphorylation	KNLHFLTTQEDYTLK CCEEEEECCCCEEEE	31.91	26074081
170	Phosphorylation	FLTTQEDYTLKIDLA EEECCCCEEEEEEHH	17.14	26074081
171	Phosphorylation	LTTQEDYTLKIDLAD EECCCCEEEEEEHHH	33.62	26074081
183	Phosphorylation	LADFEKNSRYAQYKN HHHHHHCCCCEEECC	37.42	26074081
294	Phosphorylation	TWHGWWYSLKSVVMK EECCEEEEEEHHHHC	18.66	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FGL1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FGL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FGL1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EPIPL_HUMAN	EPPK1	physical	26186194
LSG1_HUMAN	LSG1	physical	26186194
SSDH_HUMAN	ALDH5A1	physical	26186194
NAA35_HUMAN	NAA35	physical	26186194
PXDN_HUMAN	PXDN	physical	26186194
SYAM_HUMAN	AARS2	physical	26186194
NNRD_HUMAN	CARKD	physical	26186194
RAVR1_HUMAN	RAVER1	physical	26186194
TB10A_HUMAN	TBC1D10A	physical	26186194
PPIL2_HUMAN	PPIL2	physical	26186194
MAP1S_HUMAN	MAP1S	physical	26186194
UBR1_HUMAN	UBR1	physical	26186194
C19L2_HUMAN	CWF19L2	physical	26186194
AMERL_HUMAN	AMMECR1L	physical	26186194
COEA1_HUMAN	COL14A1	physical	26186194
DDB2_HUMAN	DDB2	physical	26186194
SORL_HUMAN	SORL1	physical	26186194
TF2H2_HUMAN	GTF2H2	physical	26186194
NEUA_HUMAN	CMAS	physical	26186194
TLE3_HUMAN	TLE3	physical	26186194
TLE1_HUMAN	TLE1	physical	26186194
NSUN2_HUMAN	NSUN2	physical	26186194
FBX38_HUMAN	FBXO38	physical	26186194
AFAD_HUMAN	MLLT4	physical	26186194
ARHG2_HUMAN	ARHGEF2	physical	26186194
OGFD1_HUMAN	OGFOD1	physical	26186194
PPR1A_HUMAN	PPP1R1A	physical	26186194
TSR3_HUMAN	TSR3	physical	26186194
DCA16_HUMAN	DCAF16	physical	26186194
NDUS6_HUMAN	NDUFS6	physical	26186194
NUCB1_HUMAN	NUCB1	physical	26186194
MARE2_HUMAN	MAPRE2	physical	26186194
CA198_HUMAN	C1orf198	physical	26186194
STPAP_HUMAN	TUT1	physical	26186194
TBE_HUMAN	TUBE1	physical	26186194
BORC5_HUMAN	LOH12CR1	physical	26186194
DNM1L_HUMAN	DNM1L	physical	26186194
TPA_HUMAN	PLAT	physical	26186194
PTN23_HUMAN	PTPN23	physical	26186194
CO4A2_HUMAN	COL4A2	physical	26186194
F172A_HUMAN	FAM172A	physical	26186194
ERCC3_HUMAN	ERCC3	physical	26186194
ETHE1_HUMAN	ETHE1	physical	26186194
DPYL5_HUMAN	DPYSL5	physical	26186194
GOLM1_HUMAN	GOLM1	physical	26186194
PTGR3_HUMAN	ZADH2	physical	26186194
UBA5_HUMAN	UBA5	physical	26186194
TF2H3_HUMAN	GTF2H3	physical	26186194
NPS3A_HUMAN	NIPSNAP3A	physical	26186194
MMAD_HUMAN	MMADHC	physical	26186194
TF2H1_HUMAN	GTF2H1	physical	26186194
TFP11_HUMAN	TFIP11	physical	26186194
TBD_HUMAN	TUBD1	physical	26186194
TYW4_HUMAN	LCMT2	physical	26186194
CENPC_HUMAN	CENPC	physical	26186194
TCF25_HUMAN	TCF25	physical	26186194
SPS2L_HUMAN	SPATS2L	physical	26186194
CP059_HUMAN	C16orf59	physical	26186194
SLTM_HUMAN	SLTM	physical	26186194
BORC6_HUMAN	C17orf59	physical	26186194
PKHA7_HUMAN	PLEKHA7	physical	26186194
ATX2_HUMAN	ATXN2	physical	26186194
RBM6_HUMAN	RBM6	physical	26186194
TRIP6_HUMAN	TRIP6	physical	26186194
ANKL2_HUMAN	ANKLE2	physical	26186194
RIPK1_HUMAN	RIPK1	physical	26186194
TB10A_HUMAN	TBC1D10A	physical	28514442
PPIL2_HUMAN	PPIL2	physical	28514442
ARHG2_HUMAN	ARHGEF2	physical	28514442
CA198_HUMAN	C1orf198	physical	28514442
FBX38_HUMAN	FBXO38	physical	28514442
F172A_HUMAN	FAM172A	physical	28514442
CP059_HUMAN	C16orf59	physical	28514442
TBE_HUMAN	TUBE1	physical	28514442
SSDH_HUMAN	ALDH5A1	physical	28514442
TYW4_HUMAN	LCMT2	physical	28514442
AMERL_HUMAN	AMMECR1L	physical	28514442
GOLM1_HUMAN	GOLM1	physical	28514442
AFAD_HUMAN	MLLT4	physical	28514442
ETHE1_HUMAN	ETHE1	physical	28514442
TF2H1_HUMAN	GTF2H1	physical	28514442
NNRD_HUMAN	CARKD	physical	28514442
MAP1S_HUMAN	MAP1S	physical	28514442
SYAM_HUMAN	AARS2	physical	28514442
TBD_HUMAN	TUBD1	physical	28514442
MARE2_HUMAN	MAPRE2	physical	28514442
BORC6_HUMAN	C17orf59	physical	28514442
EPIPL_HUMAN	EPPK1	physical	28514442
NUCB1_HUMAN	NUCB1	physical	28514442
PTN23_HUMAN	PTPN23	physical	28514442
DDB2_HUMAN	DDB2	physical	28514442
ERCC3_HUMAN	ERCC3	physical	28514442
OGFD1_HUMAN	OGFOD1	physical	28514442
NDUS6_HUMAN	NDUFS6	physical	28514442
SLTM_HUMAN	SLTM	physical	28514442
LSG1_HUMAN	LSG1	physical	28514442
TSR3_HUMAN	TSR3	physical	28514442
DCA16_HUMAN	DCAF16	physical	28514442
NPS3A_HUMAN	NIPSNAP3A	physical	28514442
PXDN_HUMAN	PXDN	physical	28514442
EPS8_HUMAN	EPS8	physical	28514442
DNM1L_HUMAN	DNM1L	physical	28514442
UBR1_HUMAN	UBR1	physical	28514442
RBM6_HUMAN	RBM6	physical	28514442
NAA35_HUMAN	NAA35	physical	28514442
SPS2L_HUMAN	SPATS2L	physical	28514442
NEUA_HUMAN	CMAS	physical	28514442
NSUN2_HUMAN	NSUN2	physical	28514442
PPR1A_HUMAN	PPP1R1A	physical	28514442
COEA1_HUMAN	COL14A1	physical	28514442
PTGR3_HUMAN	ZADH2	physical	28514442
RAVR1_HUMAN	RAVER1	physical	28514442
BORC5_HUMAN	LOH12CR1	physical	28514442
CENPC_HUMAN	CENPC	physical	28514442
PKHA7_HUMAN	PLEKHA7	physical	28514442
ANKL2_HUMAN	ANKLE2	physical	28514442
TF2H2_HUMAN	GTF2H2	physical	28514442
UBA5_HUMAN	UBA5	physical	28514442
TCF25_HUMAN	TCF25	physical	28514442
ATX2_HUMAN	ATXN2	physical	28514442
C19L2_HUMAN	CWF19L2	physical	28514442
STPAP_HUMAN	TUT1	physical	28514442
CO4A2_HUMAN	COL4A2	physical	28514442
TRIP6_HUMAN	TRIP6	physical	28514442
TPA_HUMAN	PLAT	physical	28514442
MMAD_HUMAN	MMADHC	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FGL1_HUMAN

Related Literatures of Post-Translational Modification