| UniProt ID | BORC6_HUMAN | |
|---|---|---|
| UniProt AC | Q96GS4 | |
| Protein Name | BLOC-1-related complex subunit 6 {ECO:0000305} | |
| Gene Name | BORCS6 {ECO:0000312|HGNC:HGNC:25939} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 357 | |
| Subcellular Localization | Lysosome membrane . | |
| Protein Description | As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.. | |
| Protein Sequence | MESSRGRPGPETDLLAVAEHQALVFGGGPGRTSSEPPAGLRVSGEEETENVGGANRHPRTSPKTSSCGVVHRPEREALENEPGPQGTLSGAGSRRGAPGAEHEPSLSSRHKNPAPPEGKPSSGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLDGLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPPSAPARPCPAPAPTPTPAIPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAVQELTALSVGCIQTYRDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEVLEALCK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 43 | Phosphorylation | PPAGLRVSGEEETEN CCCCCCCCCCCCCCC | 28985074 | ||
| 60 | Phosphorylation | GANRHPRTSPKTSSC CCCCCCCCCCCCCCC | 20068231 | ||
| 61 | Phosphorylation | ANRHPRTSPKTSSCG CCCCCCCCCCCCCCC | 20068231 | ||
| 62 | Phosphorylation | NRHPRTSPKTSSCGV CCCCCCCCCCCCCCC | 18669648 | ||
| 64 | Phosphorylation | HPRTSPKTSSCGVVH CCCCCCCCCCCCCCC | 23312004 | ||
| 65 | Phosphorylation | PRTSPKTSSCGVVHR CCCCCCCCCCCCCCC | 18669648 | ||
| 66 | Phosphorylation | RTSPKTSSCGVVHRP CCCCCCCCCCCCCCH | 23312004 | ||
| 87 | Phosphorylation | NEPGPQGTLSGAGSR CCCCCCCCCCCCCCC | 30108239 | ||
| 89 | Phosphorylation | PGPQGTLSGAGSRRG CCCCCCCCCCCCCCC | 30108239 | ||
| 93 | Phosphorylation | GTLSGAGSRRGAPGA CCCCCCCCCCCCCCC | 23401153 | ||
| 105 | Phosphorylation | PGAEHEPSLSSRHKN CCCCCCCCCCCCCCC | 28857561 | ||
| 107 | Phosphorylation | AEHEPSLSSRHKNPA CCCCCCCCCCCCCCC | 28857561 | ||
| 108 | Phosphorylation | EHEPSLSSRHKNPAP CCCCCCCCCCCCCCC | 23312004 | ||
| 122 | Phosphorylation | PPEGKPSSGRDCRRG CCCCCCCCCCCCCCC | 28555341 | ||
| 128 | Methylation | SSGRDCRRGGPGGGM CCCCCCCCCCCCCCC | - | ||
| 158 | Phosphorylation | AGSRAGRSFSSRLQD HHHHHHHHHHHHHHC | 23312004 | ||
| 160 | Phosphorylation | SRAGRSFSSRLQDSR HHHHHHHHHHHHCCC | 25159151 | ||
| 161 | Phosphorylation | RAGRSFSSRLQDSRS HHHHHHHHHHHCCCC | 28102081 | ||
| 166 | Phosphorylation | FSSRLQDSRSLDGLS HHHHHHCCCCCCCCH | 23401153 | ||
| 168 | Phosphorylation | SRLQDSRSLDGLSEA HHHHCCCCCCCCHHH | 23401153 | ||
| 173 | Phosphorylation | SRSLDGLSEACGGAG CCCCCCCHHHCCCCC | 30266825 | ||
| 181 | Phosphorylation | EACGGAGSSGSAESG HHCCCCCCCCCCCCC | 23927012 | ||
| 182 | Phosphorylation | ACGGAGSSGSAESGA HCCCCCCCCCCCCCC | 23927012 | ||
| 184 | Phosphorylation | GGAGSSGSAESGAGG CCCCCCCCCCCCCCC | 21815630 | ||
| 187 | Phosphorylation | GSSGSAESGAGGGRR CCCCCCCCCCCCCCC | 23927012 | ||
| 196 | Phosphorylation | AGGGRRATISSPLEL CCCCCCEEECCCEEE | 29255136 | ||
| 198 | Phosphorylation | GGRRATISSPLELEG CCCCEEECCCEEEEE | 30266825 | ||
| 199 | Phosphorylation | GRRATISSPLELEGT CCCEEECCCEEEEEE | 30266825 | ||
| 206 | Phosphorylation | SPLELEGTVSRHGDL CCEEEEEEEECCCCC | 23927012 | ||
| 208 | Phosphorylation | LELEGTVSRHGDLTH EEEEEEEECCCCCHH | 23403867 | ||
| 224 | Ubiquitination | VANNLQLKIRLSGAP EECCCEEEEEECCCC | 32015554 | ||
| 300 | Phosphorylation | SVGCIQTYRDAVDSL HHHHHHHHHHHHHHH | 22210691 | ||
| 313 | Sulfoxidation | SLGEAVDMSIKGMYT HHHHHHHHHHHHHHH | 21406390 | ||
| 320 | Phosphorylation | MSIKGMYTLLARCEE HHHHHHHHHHHHHHH | 22210691 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BORC6_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BORC6_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BORC6_HUMAN !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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