dbPTM

BORC8_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	BORC8_HUMAN
UniProt AC	Q96FH0
Protein Name	BLOC-1-related complex subunit 8 {ECO:0000305}
Gene Name	BORCS8 {ECO:0000312\|HGNC:HGNC:37247}
Organism	Homo sapiens (Human).
Sequence Length	119
Subcellular Localization	Lysosome membrane .
Protein Description	As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor..
Protein Sequence	MEEPEMQLKGKKVTDKFTESVYVLANEPSVALYRLQEHVRRSLPELAQHKADMQRWEEQSQGAIYTVEYACSAVKNLVDSSVYFRSVEGLLKQAISIRDHMNASAQGHSPEEPPPPSSA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
9	Ubiquitination	EEPEMQLKGKKVTDK CCCCCCCCCCCCCHH	-
18	Phosphorylation	KKVTDKFTESVYVLA CCCCHHHCCCEEHHC	25002506
20	Phosphorylation	VTDKFTESVYVLANE CCHHHCCCEEHHCCC	25002506
22	Phosphorylation	DKFTESVYVLANEPS HHHCCCEEHHCCCCC	25002506
29	Phosphorylation	YVLANEPSVALYRLQ EHHCCCCCHHHHHHH	25002506
33	Phosphorylation	NEPSVALYRLQEHVR CCCCHHHHHHHHHHH	25002506
42	Phosphorylation	LQEHVRRSLPELAQH HHHHHHHHHHHHHHH	25159151
50	Ubiquitination	LPELAQHKADMQRWE HHHHHHHHHHHHHHH	27667366
92	Ubiquitination	RSVEGLLKQAISIRD HCHHHHHHHHHHHHH	32142685
104	Phosphorylation	IRDHMNASAQGHSPE HHHHHCHHCCCCCCC	30108239
109	Phosphorylation	NASAQGHSPEEPPPP CHHCCCCCCCCCCCC	25159151
117	Phosphorylation	PEEPPPPSSA----- CCCCCCCCCC-----	23911959
118	Phosphorylation	EEPPPPSSA------ CCCCCCCCC------	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of BORC8_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of BORC8_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of BORC8_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of BORC8_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of BORC8_HUMAN

Related Literatures of Post-Translational Modification