BORC7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BORC7_HUMAN
• UniProt AC: Q96B45
• Protein Name: BLOC-1-related complex subunit 7 {ECO:0000305}
• Gene Name: BORCS7 {ECO:0000312|HGNC:HGNC:23516}
• Organism: Homo sapiens (Human).
• Sequence Length: 105
• Subcellular Localization: Lysosome membrane .
• Protein Description: As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor..
• Protein Sequence: MATGTPESQARFGQSVKGLLTEKVTTCGTDVIALTKQVLKGSRSSELLGQAARNMVLQEDAILHSEDSLRKMAIITTHLQYQQEAIQKNVEQSSDLQDQLNHLLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATGTPESQ ------CCCCCHHHH		-
3	Phosphorylation	-----MATGTPESQA -----CCCCCHHHHH		26074081
5	Phosphorylation	---MATGTPESQARF ---CCCCCHHHHHHH		30576142
6	Phosphorylation	--MATGTPESQARFG --CCCCCHHHHHHHC		19413330
8	Phosphorylation	MATGTPESQARFGQS CCCCCHHHHHHHCHH		26074081
18	Ubiquitination	RFGQSVKGLLTEKVT HHCHHHHHHHHHCCC		-
36	Ubiquitination	TDVIALTKQVLKGSR HHHHHHHHHHHHCCC		-
37	Ubiquitination	DVIALTKQVLKGSRS HHHHHHHHHHHCCCC		-
42	Phosphorylation	TKQVLKGSRSSELLG HHHHHHCCCCHHHHH		25159151
44	Phosphorylation	QVLKGSRSSELLGQA HHHHCCCCHHHHHHH		30266825
45	Phosphorylation	VLKGSRSSELLGQAA HHHCCCCHHHHHHHH		30266825
46	Phosphorylation	LKGSRSSELLGQAAR HHCCCCHHHHHHHHH		18669648
65	Phosphorylation	QEDAILHSEDSLRKM CHHHHHCCHHHHHHH		27251275
68	Phosphorylation	AILHSEDSLRKMAII HHHCCHHHHHHHHHH		26091039
69	Phosphorylation	ILHSEDSLRKMAIIT HHCCHHHHHHHHHHH		27251275
106	Ubiquitination	QLNHLLK-------- HHHHHHC--------		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BORC7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BORC7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BORC7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of BORC7_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.