ZNF2_HUMAN - dbPTM
ZNF2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZNF2_HUMAN
UniProt AC Q9BSG1
Protein Name Zinc finger protein 2
Gene Name ZNF2
Organism Homo sapiens (Human).
Sequence Length 426
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MAAVSPTTRCQESVTFEDVAVVFTDEEWSRLVPIQRDLYKEVMLENYNSIVSLGLPVPQPDVIFQLKRGDKPWMVDLHGSEEREWPESVSLDWETKPEIHDASDKKSEGSLRECLGRQSPLCPKFEVHTPNGRMGTEKQSPSGETRKKSLSRDKGLRRRRSALSREILTKERHQECSDCGKTFFDHSSLTRHQRTHTGEKPYDCRECGKAFSHRSSLSRHLMSHTGESPYECSVCSKAFFDRSSLTVHQRIHTGEKPFQCNECGKAFFDRSSLTRHQRIHTGESPYECHQCGKAFSQKSILTRHQLIHTGRKPYECNECGKAFYGVSSLNRHQKAHAGDPRYQCNECGKAFFDRSSLTQHQKIHTGDKPYECSECGKAFSQRCRLTRHQRVHTGEKPFECTVCGKVFSSKSSVIQHQRRYAKQGID
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MAAVSPTTRCQE
---CCCCCCCCCCCC
16.2929255136
7Phosphorylation-MAAVSPTTRCQESV
-CCCCCCCCCCCCCC
21.2625850435
8PhosphorylationMAAVSPTTRCQESVT
CCCCCCCCCCCCCCC
32.6025850435
118PhosphorylationLRECLGRQSPLCPKF
HHHHHCCCCCCCCCE
47.8323882029
119PhosphorylationRECLGRQSPLCPKFE
HHHHCCCCCCCCCEE
20.6230266825
121PhosphorylationCLGRQSPLCPKFEVH
HHCCCCCCCCCEEEE
10.6627174698
126PhosphorylationSPLCPKFEVHTPNGR
CCCCCCEEEECCCCC
39.2423882029
136PhosphorylationTPNGRMGTEKQSPSG
CCCCCCCCCCCCCCC
30.5728450419
140PhosphorylationRMGTEKQSPSGETRK
CCCCCCCCCCCHHHH
31.9125849741
142PhosphorylationGTEKQSPSGETRKKS
CCCCCCCCCHHHHHH
55.2828450419
145PhosphorylationKQSPSGETRKKSLSR
CCCCCCHHHHHHHHH
51.8425002506
160 (in isoform 2)Phosphorylation-31.5823882029
160PhosphorylationDKGLRRRRSALSREI
HHHHHHHHHHHHHHH
31.58-
163 (in isoform 2)Phosphorylation-27.8127174698
168 (in isoform 2)Phosphorylation-36.2023882029
187PhosphorylationGKTFFDHSSLTRHQR
CCCCCCCHHCCCCCC
30.2728555341
188PhosphorylationKTFFDHSSLTRHQRT
CCCCCCHHCCCCCCC
5.6728555341
195PhosphorylationSLTRHQRTHTGEKPY
HCCCCCCCCCCCCCC
33.78-
197PhosphorylationTRHQRTHTGEKPYDC
CCCCCCCCCCCCCCH
33.07-
215PhosphorylationGKAFSHRSSLSRHLM
HHHHCCHHHHHHHHH
30.2618691976
216PhosphorylationKAFSHRSSLSRHLMS
HHHCCHHHHHHHHHH
5.7120068231
218PhosphorylationFSHRSSLSRHLMSHT
HCCHHHHHHHHHHHC
32.0521406692
225PhosphorylationSRHLMSHTGESPYEC
HHHHHHHCCCCCCCC
28.1428555341
243PhosphorylationSKAFFDRSSLTVHQR
CCCEECCCCCEEEEE
29.0228555341
253PhosphorylationTVHQRIHTGEKPFQC
EEEEECCCCCCCEEC
27.11-
272PhosphorylationKAFFDRSSLTRHQRI
CEEECCHHCCCCCCC
5.2825690035
281PhosphorylationTRHQRIHTGESPYEC
CCCCCCCCCCCCCHH
21.1528152594
284PhosphorylationQRIHTGESPYECHQC
CCCCCCCCCCHHHCC
25.3328152594
286PhosphorylationIHTGESPYECHQCGK
CCCCCCCCHHHCCCC
28.9828152594
298PhosphorylationCGKAFSQKSILTRHQ
CCCCCCCCCHHHHHH
18.3924719451
299PhosphorylationGKAFSQKSILTRHQL
CCCCCCCCHHHHHHH
6.1624719451
302PhosphorylationFSQKSILTRHQLIHT
CCCCCHHHHHHHHHC
16.4720860994
328PhosphorylationKAFYGVSSLNRHQKA
CEEECHHHCCHHHHH
5.2028555341
330UbiquitinationFYGVSSLNRHQKAHA
EECHHHCCHHHHHHC
38.62-
373PhosphorylationGDKPYECSECGKAFS
CCCCCCCCHHHHHHH
59.9730631047
393PhosphorylationTRHQRVHTGEKPFEC
CCCCCCCCCCCCEEE
26.50-
411PhosphorylationGKVFSSKSSVIQHQR
CEEECCCHHHHHHHH
27.29-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZNF2_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZNF2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZNF2_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
ANM5_HUMANPRMT5physical
23455924
TSG10_HUMANTSGA10physical
25416956
KR107_HUMANKRTAP10-7physical
25416956
PUM3_HUMANKIAA0020physical
28514442
ZFP62_HUMANZFP62physical
28514442
TAF1B_HUMANTAF1Bphysical
28514442
ZN800_HUMANZNF800physical
28514442
RRP8_HUMANRRP8physical
28514442
BUD13_HUMANBUD13physical
28514442
RPF2_HUMANRPF2physical
28514442
ZN770_HUMANZNF770physical
28514442
GLYR1_HUMANGLYR1physical
28514442
RL37A_HUMANRPL37Aphysical
28514442
DDX10_HUMANDDX10physical
28514442
CDK12_HUMANCDK12physical
28514442
TAF1D_HUMANTAF1Dphysical
28514442
BRX1_HUMANBRIX1physical
28514442
RBM28_HUMANRBM28physical
28514442
NOG2_HUMANGNL2physical
28514442
MAK16_HUMANMAK16physical
28514442
NSD2_HUMANWHSC1physical
28514442
RT35_HUMANMRPS35physical
28514442
RBM34_HUMANRBM34physical
28514442
MPP10_HUMANMPHOSPH10physical
28514442
DHX30_HUMANDHX30physical
28514442
ZN121_HUMANZNF121physical
28514442
PAPD5_HUMANPAPD5physical
28514442
ZN184_HUMANZNF184physical
28514442
NOC3L_HUMANNOC3Lphysical
28514442
IMP4_HUMANIMP4physical
28514442
RBM19_HUMANRBM19physical
28514442
DDX54_HUMANDDX54physical
28514442
ZN189_HUMANZNF189physical
28514442
DKC1_HUMANDKC1physical
28514442
PTCD3_HUMANPTCD3physical
28514442
RRS1_HUMANRRS1physical
28514442
ZN771_HUMANZNF771physical
28514442
TDIF2_HUMANDNTTIP2physical
28514442
ZCCHV_HUMANZC3HAV1physical
28514442
ZNF22_HUMANZNF22physical
28514442
RL3_HUMANRPL3physical
28514442
CENPU_HUMANCENPUphysical
28514442
SAS10_HUMANUTP3physical
28514442
NOG1_HUMANGTPBP4physical
28514442
PRP4B_HUMANPRPF4Bphysical
28514442
ZCHC9_HUMANZCCHC9physical
28514442
CI114_HUMANC9orf114physical
28514442
RT09_HUMANMRPS9physical
28514442
DDX31_HUMANDDX31physical
28514442
NOP56_HUMANNOP56physical
28514442
PRD15_HUMANPRDM15physical
28514442
ZSC25_HUMANZSCAN25physical
28514442
REXO4_HUMANREXO4physical
28514442
PK1IP_HUMANPAK1IP1physical
28514442
RL7A_HUMANRPL7Aphysical
28514442
DDX24_HUMANDDX24physical
28514442
CEBPZ_HUMANCEBPZphysical
28514442
AATF_HUMANAATFphysical
28514442
RS3A_HUMANRPS3Aphysical
28514442
RM52_HUMANMRPL52physical
28514442
BMS1_HUMANBMS1physical
28514442
HERC5_HUMANHERC5physical
28514442
RT07_HUMANMRPS7physical
28514442
RL17_HUMANRPL17physical
28514442
CC137_HUMANCCDC137physical
28514442
CTCF_HUMANCTCFphysical
28514442
STAU2_HUMANSTAU2physical
28514442
CDK13_HUMANCDK13physical
28514442

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZNF2_HUMAN

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Related Literatures of Post-Translational Modification

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