YL352_YEAST - dbPTM
YL352_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YL352_YEAST
UniProt AC Q06479
Protein Name F-box protein YLR352W
Gene Name YLR352W
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 807
Subcellular Localization
Protein Description Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins (By similarity)..
Protein Sequence MPDLKSKTLSSQSLGAAIPPEIVYQILTYQFRDLLRNDHPGTAEKFNENLTTFVKSNLTVNKTFSHICQVLIYRYCNLTTAKRFHGLLQTLKGNRCLCNKIEVADFQELTSIGLGRSSEMNKMIKNLTNETLLEFLMLTKANLREFLACENIQDDLDDNIIKYILSPGKVLSVVDFCGCSGTTFTESFIKALDKYYPNKSIDQYRLEPIQQNYQITCLGLNDCIDLPSHVLWKILKMLPELQKLDLSHTSIDDSTLYHGIPHWKNLTHLSLATCLQVTPRAVLEFFSHHPTITDPDNTSTLEWLNVSVIAHSSSWNEVHTMFLLKKLCQHGHNKTLQYLNIGGLPLHVAPSFGEDPISESTYYYQCRDSLQFIKWNFPKLKSLSIKGNSIPISTLVEFLTPIDQDHPNCAQKLKFLNISGNSYVNKWTIQDSLLYTCSPSLVALEVSFDSWQQIEKLNDRHEIIAYRYKNPNSVIKDISTAEQVKWKCYIDSSYGRRYWLYKTDPFLNRDDLDSKSNLTRYDFEGHKIIEIINQPDFLKFAQSKIMLGCGLVPQSGIRRKLCYRDLKPPVSQFLNRKGAISLGDTPLPIITPTLPRGGWRIIHNEDDNNSHVEDSQNHVNAIPRRNSLLSRPTLRSNNGSSSANPFAINVSPASQIRDGLYWDRSVHDLRELSLQEQRIQELADEQQELRTIANFEETDDEYLHDPDLQRRRSQLHLFESSRSRSGNKTRPSLTGEHSSSASFLSFSHFNHLHKRKNYYFTHPDEFVYDPKDPLTTQRYRLHFEIVNEYQVFGCIERGMYRYYSLKA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
627PhosphorylationNAIPRRNSLLSRPTL
CCCCCCCCHHHCCEE		28.9529136822
641PhosphorylationLRSNNGSSSANPFAI
ECCCCCCCCCCCEEE		34.5630377154
642PhosphorylationRSNNGSSSANPFAIN
CCCCCCCCCCCEEEE		33.4930377154
665PhosphorylationDGLYWDRSVHDLREL
CCCCCCCCHHHHHHH		22.7228889911
698PhosphorylationTIANFEETDDEYLHD
HHHCCCCCCCHHHCC		41.3728889911
713PhosphorylationPDLQRRRSQLHLFES
HHHHHHHHHHHHHHC		34.9722369663
802PhosphorylationIERGMYRYYSLKA--
EECCCCEEEECCC--		4.6627017623
803PhosphorylationERGMYRYYSLKA---
ECCCCEEEECCC---		9.8727017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YL352_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YL352_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YL352_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SKP1_YEASTSKP1physical
11805837
CDC53_YEASTCDC53physical
11805837
SSB1_YEASTSSB1genetic
20093466
GLT1_YEASTGLT1genetic
20093466
PEX19_YEASTPEX19genetic
20093466
PLP1_YEASTPLP1genetic
20093466
YPR1_YEASTYPR1genetic
20093466
RL29_YEASTRPL29genetic
20093466
SHE10_YEASTSHE10genetic
20093466
ARO8_YEASTARO8genetic
20093466
RRT6_YEASTRRT6genetic
20093466
ROG1_YEASTROG1genetic
20093466
YG036_YEASTYGL036Wgenetic
20093466
CGR1_YEASTCGR1genetic
20093466
RS25A_YEASTRPS25Agenetic
20093466
TWF1_YEASTTWF1genetic
20093466
SCW4_YEASTSCW4genetic
20093466
MAL12_YEASTMAL12genetic
20093466
SODM_YEASTSOD2genetic
20093466
PDR11_YEASTPDR11genetic
20093466
IME1_YEASTIME1genetic
20093466
XPT1_YEASTXPT1genetic
20093466
DCOR_YEASTSPE1genetic
20093466
LOT5_YEASTLOT5genetic
20093466
TRM2_YEASTTRM2genetic
20093466
GEX2_YEASTGEX2genetic
20093466
CTK3_YEASTCTK3genetic
20093466
MIX17_YEASTMIX17genetic
20093466
IMP2_YEASTIMP2genetic
20093466
ERG2_YEASTERG2genetic
20093466
SUR1_YEASTSUR1genetic
20093466
PABC_YEASTABZ2genetic
27708008
CDC1_YEASTCDC1genetic
27708008
TAF6_YEASTTAF6genetic
27708008
SDA1_YEASTSDA1genetic
27708008
ORC6_YEASTORC6genetic
27708008
KTHY_YEASTCDC8genetic
27708008
YJ9I_YEASTYJR141Wgenetic
27708008
NOP2_YEASTNOP2genetic
27708008
APC5_YEASTAPC5genetic
27708008
PEX19_YEASTPEX19genetic
27708008
DTD_YEASTDTD1genetic
27708008
PLP1_YEASTPLP1genetic
27708008
YPR1_YEASTYPR1genetic
27708008
HKR1_YEASTHKR1genetic
27708008
STL1_YEASTSTL1genetic
27708008
CAJ1_YEASTCAJ1genetic
27708008
DSE1_YEASTDSE1genetic
27708008
RAD4_YEASTRAD4genetic
27708008
FAR7_YEASTFAR7genetic
27708008
FAB1_YEASTFAB1genetic
27708008
RT31_YEASTYMR31genetic
27708008
CGR1_YEASTCGR1genetic
27708008
YG036_YEASTYGL036Wgenetic
27708008
ROG1_YEASTROG1genetic
27708008
FKS2_YEASTGSC2genetic
27708008
SODM_YEASTSOD2genetic
27708008
VPS29_YEASTVPS29genetic
27708008
IME1_YEASTIME1genetic
27708008
XPT1_YEASTXPT1genetic
27708008
LOT5_YEASTLOT5genetic
27708008
TRM2_YEASTTRM2genetic
27708008
YL046_YEASTYLR046Cgenetic
27708008
CTK3_YEASTCTK3genetic
27708008
ELP6_YEASTELP6genetic
27708008
YM94_YEASTYMR315Wgenetic
27708008
YM96_YEASTYMR317Wgenetic
27708008
SIW14_YEASTSIW14genetic
27708008
CMC1_YEASTSAL1genetic
27708008
MKT1_YEASTMKT1genetic
27708008
YPQ1_YEASTYPQ1genetic
27708008
HMI1_YEASTHMI1genetic
27708008
DIA2_YEASTDIA2genetic
27708008
SGF11_YEASTSGF11genetic
27708008
SUR1_YEASTSUR1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YL352_YEAST

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Related Literatures of Post-Translational Modification

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