F174A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F174A_HUMAN
• UniProt AC: Q8TBP5
• Protein Name: Membrane protein FAM174A
• Gene Name: FAM174A
• Organism: Homo sapiens (Human).
• Sequence Length: 190
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MKASQCCCCLSHLLASVLLLLLLPELSGPLAVLLQAAEAAPGLGPPDPRPRTLPPLPPGPTPAQQPGRGLAEAAGPRGSEGGNGSNPVAGLETDDHGGKAGEGSVGGGLAVSPNPGDKPMTQRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPLEQDDEDDDNTLFDANHPRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	O-linked_Glycosylation	PPDPRPRTLPPLPPG CCCCCCCCCCCCCCC	46.42	55830749
61	O-linked_Glycosylation	PPLPPGPTPAQQPGR CCCCCCCCCCCCCCC	36.85	55830755
83	N-linked_Glycosylation	PRGSEGGNGSNPVAG CCCCCCCCCCCCCCC	62.67	UniProtKB CARBOHYD
132	Phosphorylation	LTVLMVVSGAVLVYF HHHHHHHCHHHHHHH	15.04	-
138	Phosphorylation	VSGAVLVYFVVRTVR HCHHHHHHHHHHHHH	6.11	-
169	Phosphorylation	NIENMELTPLEQDDE CCCCCEECCCCCCCC	16.72	24275569

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F174A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F174A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F174A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PEX19_HUMAN	PEX19	physical	28514442
TM168_HUMAN	TMEM168	physical	28514442
TAM41_HUMAN	TAMM41	physical	28514442
TTK_HUMAN	TTK	physical	28514442
S39AB_HUMAN	SLC39A11	physical	28514442
COQ5_HUMAN	COQ5	physical	28514442
F118B_HUMAN	FAM118B	physical	28514442
AT2B4_HUMAN	ATP2B4	physical	28514442
GUF1_HUMAN	GUF1	physical	28514442
PPTC7_HUMAN	PPTC7	physical	28514442
GOPC_HUMAN	GOPC	physical	28514442
HS12A_HUMAN	HSPA12A	physical	28514442
UH1BL_HUMAN	UHRF1BP1L	physical	28514442
SYHM_HUMAN	HARS2	physical	28514442
PDC10_HUMAN	PDCD10	physical	28514442
TBB3_HUMAN	TUBB3	physical	28514442
AB17B_HUMAN	ABHD17B	physical	28514442
PEX1_HUMAN	PEX1	physical	28514442
JIP4_HUMAN	SPAG9	physical	28514442
DJC11_HUMAN	DNAJC11	physical	28514442
UGDH_HUMAN	UGDH	physical	28514442
CBWD1_HUMAN	CBWD1	physical	28514442
FAKD1_HUMAN	FASTKD1	physical	28514442
CAND2_HUMAN	CAND2	physical	28514442
LTN1_HUMAN	LTN1	physical	28514442
MD2L2_HUMAN	MAD2L2	physical	28514442
NF1_HUMAN	NF1	physical	28514442
SPG7_HUMAN	SPG7	physical	28514442
CNDH2_HUMAN	NCAPH2	physical	28514442
TBB8_HUMAN	TUBB8	physical	28514442
AT12A_HUMAN	ATP12A	physical	28514442
INT2_HUMAN	INTS2	physical	28514442
STK26_HUMAN	STK26	physical	28514442
GPD1L_HUMAN	GPD1L	physical	28514442
GAK_HUMAN	GAK	physical	28514442
MAP1S_HUMAN	MAP1S	physical	28514442
PDXD1_HUMAN	PDXDC1	physical	28514442
TNPO2_HUMAN	TNPO2	physical	28514442
CTU2_HUMAN	CTU2	physical	28514442
OPA1_HUMAN	OPA1	physical	28514442
RA51C_HUMAN	RAD51C	physical	28514442
GNL3L_HUMAN	GNL3L	physical	28514442
NOCT_HUMAN	CCRN4L	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.