F118B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F118B_HUMAN
• UniProt AC: Q9BPY3
• Protein Name: Protein FAM118B
• Gene Name: FAM118B
• Organism: Homo sapiens (Human).
• Sequence Length: 351
• Subcellular Localization: Nucleus, Cajal body .
• Protein Description: May play a role in Cajal bodies formation..
• Protein Sequence: MASTGSQASDIDEIFGFFNDGEPPTKKPRKLLPSLKTKKPRELVLVIGTGISAAVAPQVPALKSWKGLIQALLDAAIDFDLLEDEESKKFQKCLHEDKNLVHVAHDLIQKLSPRTSNVRSTFFKDCLYEVFDDLESKMEDSGKQLLQSVLHLMENGALVLTTNFDNLLELYAADQGKQLESLDLTDEKKVLEWAQEKRKLSVLHIHGVYTNPSGIVLHPAGYQNVLRNTEVMREIQKLYENKSFLFLGCGWTVDDTTFQALFLEAVKHKSDLEHFMLVRRGDVDEFKKLRENMLDKGIKVISYGDDYADLPEYFKRLTCEISTRGTSAGMVREGQLNGSSAAHSEIRGCST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASTGSQAS ------CCCCCCCCH	18.79	21406692
3	Phosphorylation	-----MASTGSQASD -----CCCCCCCCHH	31.81	23663014
4	Phosphorylation	----MASTGSQASDI ----CCCCCCCCHHH	31.17	25159151
6	Phosphorylation	--MASTGSQASDIDE --CCCCCCCCHHHHH	23.74	25159151
9	Phosphorylation	ASTGSQASDIDEIFG CCCCCCCHHHHHHHC	27.71	25159151
25	Phosphorylation	FNDGEPPTKKPRKLL CCCCCCCCCCCHHCC	63.52	20873877
34	Phosphorylation	KPRKLLPSLKTKKPR CCHHCCCCCCCCCCC	42.33	24719451
112	Phosphorylation	HDLIQKLSPRTSNVR HHHHHHHCCCCCCCH	21.26	29523821
128	Phosphorylation	TFFKDCLYEVFDDLE HHHHHHHHHHHHHHH	19.17	24114839
136	Phosphorylation	EVFDDLESKMEDSGK HHHHHHHHHCHHHHH	44.60	24114839
141	Phosphorylation	LESKMEDSGKQLLQS HHHHCHHHHHHHHHH	34.29	-
188	Ubiquitination	SLDLTDEKKVLEWAQ CCCCCCHHHHHHHHH	51.49	-
189	Ubiquitination	LDLTDEKKVLEWAQE CCCCCHHHHHHHHHH	50.43	-
197	Ubiquitination	VLEWAQEKRKLSVLH HHHHHHHHHCCEEEE	42.63	-
287	Ubiquitination	RGDVDEFKKLRENML CCCHHHHHHHHHHHH	49.18	-
296	Acetylation	LRENMLDKGIKVISY HHHHHHHCCCEEEEE	59.58	25953088
299	Ubiquitination	NMLDKGIKVISYGDD HHHHCCCEEEEECCC	42.03	-
303	Phosphorylation	KGIKVISYGDDYADL CCCEEEEECCCHHHH	17.28	28152594
307	Phosphorylation	VISYGDDYADLPEYF EEEECCCHHHHHHHH	13.52	28152594
313	Phosphorylation	DYADLPEYFKRLTCE CHHHHHHHHHHHHEE	16.68	26503514
315	Ubiquitination	ADLPEYFKRLTCEIS HHHHHHHHHHHEEEE	45.67	21906983
327	Phosphorylation	EISTRGTSAGMVREG EEECCCCCCCEEEEC	26.16	24850871

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F118B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F118B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F118B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SPRE1_HUMAN	SPRED1	physical	21900206
CEP70_HUMAN	CEP70	physical	21900206
TIP_HUMAN	ITFG1	physical	21900206
CATB_HUMAN	CTSB	physical	21900206
MED31_HUMAN	MED31	physical	21900206
VIME_HUMAN	VIM	physical	21900206
CE126_HUMAN	KIAA1377	physical	21900206
TYB4_HUMAN	TMSB4X	physical	21900206
GBB2_HUMAN	GNB2	physical	21900206
GANP_HUMAN	MCM3AP	physical	21900206
SHC1_HUMAN	SHC1	physical	21900206
FA20C_HUMAN	FAM20C	physical	21900206
ING5_HUMAN	ING5	physical	21900206
SYQ_HUMAN	QARS	physical	21900206
ZN746_HUMAN	ZNF746	physical	21900206
SEM5B_HUMAN	SEMA5B	physical	21900206
RBM48_HUMAN	RBM48	physical	21900206
NGEF_HUMAN	NGEF	physical	21900206
SETB1_HUMAN	SETDB1	physical	21900206
ZN235_HUMAN	ZNF235	physical	21900206
DECR_HUMAN	DECR1	physical	28514442
KCNJ6_HUMAN	KCNJ6	physical	28514442
LAMP2_HUMAN	LAMP2	physical	28514442
EPHA3_HUMAN	EPHA3	physical	28514442
EPHA4_HUMAN	EPHA4	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.