PPTC7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPTC7_HUMAN
• UniProt AC: Q8NI37
• Protein Name: Protein phosphatase PTC7 homolog
• Gene Name: PPTC7
• Organism: Homo sapiens (Human).
• Sequence Length: 304
• Protein Sequence: MFSVLSYGRLVARAVLGGLSQTDPRAGGGGGGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPIGILTTSYCELLQNKVPLLGSSTACIVVLDRTSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVVLSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQQTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Ubiquitination	FRKGLLKKGACYGDD HHHCHHHCCCCCCCC	52.27	-
153	Phosphorylation	RTSHRLHTANLGDSG CCCCEEEECCCCCCC	23.10	-
239	Ubiquitination	YMILQELKKLKNSNY HHHHHHHHHHHCCCH	56.14	22817900
240	Ubiquitination	MILQELKKLKNSNYE HHHHHHHHHHCCCHH	76.85	22817900
242	Ubiquitination	LQELKKLKNSNYESI HHHHHHHHCCCHHHH	68.18	22817900
252	Phosphorylation	NYESIQQTARSIAEQ CHHHHHHHHHHHHHH	13.99	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPTC7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPTC7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPTC7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PPTC7_HUMAN	PPTC7	physical	27499296
BNIP3_HUMAN	BNIP3	physical	27499296
BNI3L_HUMAN	BNIP3L	physical	27499296
TR61B_HUMAN	TRMT61B	physical	27499296
TRM2_HUMAN	TRMT2B	physical	27499296
RM22_HUMAN	MRPL22	physical	27499296
RT18C_HUMAN	MRPS18C	physical	27499296
SYSM_HUMAN	SARS2	physical	27499296
SPKAP_HUMAN	SPHKAP	physical	27499296
C1QBP_HUMAN	C1QBP	physical	27499296
RT4I1_HUMAN	RTN4IP1	physical	28514442
TRM2_HUMAN	TRMT2B	physical	28514442
ASF1A_HUMAN	ASF1A	physical	28514442
TR61B_HUMAN	TRMT61B	physical	28514442
ODB2_HUMAN	DBT	physical	28514442
HSDL1_HUMAN	HSDL1	physical	28514442
UBB_HUMAN	UBB	physical	28514442
AIFM1_HUMAN	AIFM1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.