| UniProt ID | BAG2_MOUSE | |
|---|---|---|
| UniProt AC | Q91YN9 | |
| Protein Name | BAG family molecular chaperone regulator 2 | |
| Gene Name | Bag2 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 210 | |
| Subcellular Localization | ||
| Protein Description | Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release.. | |
| Protein Sequence | MAQAKISAKAHEGRFCRSSSMADRSSRLLESLDQLELRVEALRDAATAVEQEKEILLEMIHSIQNSQDMRQISDGEREELNLTANRLMGRTLTVEVSVETIRNPQQEESLKHATRIIDEVVSKFLDDLGNAKSHLMSLYSACSSEVPPGPVDQKFQSIVIGCALEDQKKIKRRLETLLRNIDNSDKAIKLLEHAKGAGSKSLQNTDGKFN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MAQAKISAK ------CCCCHHCCH | 20.31 | - | |
| 7 | Phosphorylation | -MAQAKISAKAHEGR -CCCCHHCCHHCCCC | 24.02 | 29514104 | |
| 18 | Phosphorylation | HEGRFCRSSSMADRS CCCCCCCCHHHHHHH | 28.13 | 27717184 | |
| 20 | Phosphorylation | GRFCRSSSMADRSSR CCCCCCHHHHHHHHH | 21.16 | 23737553 | |
| 25 | Phosphorylation | SSSMADRSSRLLESL CHHHHHHHHHHHHHH | 21.98 | 25338131 | |
| 31 | Phosphorylation | RSSRLLESLDQLELR HHHHHHHHHHHHHHH | 36.90 | 28066266 | |
| 73 | Phosphorylation | SQDMRQISDGEREEL CHHHHHCCCCCHHHH | 31.09 | 26824392 | |
| 123 | Ubiquitination | IIDEVVSKFLDDLGN HHHHHHHHHHHHHCC | 38.03 | - | |
| 168 | Acetylation | GCALEDQKKIKRRLE HHCCCCHHHHHHHHH | 69.64 | 130391 | |
| 184 | Phosphorylation | LLRNIDNSDKAIKLL HHHCCCCHHHHHHHH | 36.42 | 18779572 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BAG2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BAG2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BAG2_MOUSE !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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