TSN17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TSN17_HUMAN
• UniProt AC: Q96FV3
• Protein Name: Tetraspanin-17
• Gene Name: TSPAN17
• Organism: Homo sapiens (Human).
• Sequence Length: 270
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: Regulates ADAM10 maturation..
• Protein Sequence: MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQNLVSDIKAVKANW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	N-linked_Glycosylation	GEKGVLSNISALTDL HHCCHHHCHHHHHHC	28.24	UniProtKB CARBOHYD
90	Phosphorylation	IGALRENTFLLKFFS HHHHHHCHHHHHHHH	15.77	30301811
171	N-linked_Glycosylation	WNLNIYFNCTDLNPS CCEEEEEECCCCCCC	15.71	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TSN17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TSN17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TSN17_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HACD3_HUMAN	PTPLAD1	physical	17353931
ADA10_HUMAN	ADAM10	physical	23091066
AT2A3_HUMAN	ATP2A3	physical	26186194
PLPL6_HUMAN	PNPLA6	physical	26186194
DGKE_HUMAN	DGKE	physical	26186194
TBL2_HUMAN	TBL2	physical	26186194
RETST_HUMAN	RETSAT	physical	26186194
DHRS7_HUMAN	DHRS7	physical	26186194
TYW1_HUMAN	TYW1	physical	26186194
GHDC_HUMAN	GHDC	physical	26186194
PLCD_HUMAN	AGPAT4	physical	26186194
CTL1_HUMAN	SLC44A1	physical	26186194
PLCC_HUMAN	AGPAT3	physical	26186194
ACV1B_HUMAN	ACVR1B	physical	26186194
CP51A_HUMAN	CYP51A1	physical	26186194
GPM6A_HUMAN	GPM6A	physical	26186194
GPAT4_HUMAN	AGPAT6	physical	26186194
KDSR_HUMAN	KDSR	physical	26186194
HS2ST_HUMAN	HS2ST1	physical	26186194
HYEP_HUMAN	EPHX1	physical	26186194
TMUB1_HUMAN	TMUB1	physical	26186194
UPK3L_HUMAN	UPK3BL	physical	26186194
BMR1A_HUMAN	BMPR1A	physical	26186194
RN149_HUMAN	RNF149	physical	26186194
GPAT3_HUMAN	AGPAT9	physical	26186194
BSCL2_HUMAN	BSCL2	physical	26186194
SC5D_HUMAN	SC5D	physical	26186194
GBB4_HUMAN	GNB4	physical	26186194
CXA1_HUMAN	GJA1	physical	26186194
MET7A_HUMAN	METTL7A	physical	26186194
F210B_HUMAN	FAM210B	physical	26186194
CC115_HUMAN	CCDC115	physical	26186194
F189B_HUMAN	FAM189B	physical	26186194
RETR3_HUMAN	FAM134C	physical	26186194
TM2D3_HUMAN	TM2D3	physical	26186194
TM199_HUMAN	TMEM199	physical	26186194
THEM6_HUMAN	THEM6	physical	26186194
PRAF2_HUMAN	PRAF2	physical	26186194
GP1BB_HUMAN	GP1BB	physical	26186194
KCNJ8_HUMAN	KCNJ8	physical	26186194
GOLI_HUMAN	RNF130	physical	26186194
MET7A_HUMAN	METTL7A	physical	28514442
CTL1_HUMAN	SLC44A1	physical	28514442
F210B_HUMAN	FAM210B	physical	28514442
TM199_HUMAN	TMEM199	physical	28514442
CC115_HUMAN	CCDC115	physical	28514442
GHDC_HUMAN	GHDC	physical	28514442
TYW1_HUMAN	TYW1	physical	28514442
AT2A3_HUMAN	ATP2A3	physical	28514442
RETR3_HUMAN	FAM134C	physical	28514442
HYEP_HUMAN	EPHX1	physical	28514442
GP1BB_HUMAN	GP1BB	physical	28514442
PLCC_HUMAN	AGPAT3	physical	28514442
BSCL2_HUMAN	BSCL2	physical	28514442
F189B_HUMAN	FAM189B	physical	28514442
DHRS7_HUMAN	DHRS7	physical	28514442
PRAF2_HUMAN	PRAF2	physical	28514442
SGCB_HUMAN	SGCB	physical	28514442
UPK3L_HUMAN	UPK3BL	physical	28514442
RN149_HUMAN	RNF149	physical	28514442
PLPL6_HUMAN	PNPLA6	physical	28514442
CP51A_HUMAN	CYP51A1	physical	28514442
TM2D3_HUMAN	TM2D3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.