PLCD_HUMAN - dbPTM
PLCD_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PLCD_HUMAN
UniProt AC Q9NRZ5
Protein Name 1-acyl-sn-glycerol-3-phosphate acyltransferase delta
Gene Name AGPAT4
Organism Homo sapiens (Human).
Sequence Length 378
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone..
Protein Sequence MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLND
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
84UbiquitinationTDPRAYLKYGKENAI
CCHHHHHHHCCCCEE		39.0022817900
87UbiquitinationRAYLKYGKENAIVVL
HHHHHHCCCCEEEEE		44.7122817900
119UbiquitinationFGLLGGSKVLAKKEL
HCCCCCCCHHCCHHH		44.5421906983
142UbiquitinationMWYFTEMVFCSRKWE
HHHHHHHHHHCCCHH		3.4022817900
147UbiquitinationEMVFCSRKWEQDRKT
HHHHHCCCHHHHHHH		38.5022817900
153MalonylationRKWEQDRKTVATSLQ
CCHHHHHHHHHHHHH		56.4926320211
181PhosphorylationHCEGTRFTEKKHEIS
EECCCCCCCCCHHHH		43.5426074081
188PhosphorylationTEKKHEISMQVARAK
CCCCHHHHHHHHHHC		10.5226074081
201UbiquitinationAKGLPRLKHHLLPRT
HCCCCHHHHHCCCCC		30.2029967540
222UbiquitinationVRSLRNVVSAVYDCT
HHHHHHHHHHHEEEE		3.2922817900
223PhosphorylationRSLRNVVSAVYDCTL
HHHHHHHHHHEEEEE		14.03108826551
226PhosphorylationRNVVSAVYDCTLNFR
HHHHHHHEEEEEECC		12.6726434776
227UbiquitinationNVVSAVYDCTLNFRN
HHHHHHEEEEEECCC		16.6022817900
229PhosphorylationVSAVYDCTLNFRNNE
HHHHEEEEEECCCCC		23.1026434776
276UbiquitinationECSAWLHKLYQEKDA
HHHHHHHHHHHCCHH		46.8722817900
281UbiquitinationLHKLYQEKDAFQEEY
HHHHHHCCHHHHHHH		38.5422817900
332PhosphorylationFLVSMIRSGSSLTLA
HHHHHHHCCCCHHHH		31.9146160499
334PhosphorylationVSMIRSGSSLTLASF
HHHHHCCCCHHHHHH		24.3446160505
335PhosphorylationSMIRSGSSLTLASFI
HHHHCCCCHHHHHHH		28.9746160511
365PhosphorylationVTEIDKGSAYGNSDS
CEEECCCCCCCCCCC		24.8646160517
367PhosphorylationEIDKGSAYGNSDSKQ
EECCCCCCCCCCCCC		20.6646160523
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PLCD_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PLCD_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PLCD_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PLCD_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PLCD_HUMAN

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Related Literatures of Post-Translational Modification

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