SPP2_SCHPO - dbPTM
SPP2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPP2_SCHPO
UniProt AC O43031
Protein Name Pre-mRNA-splicing factor cwf28
Gene Name cwf28
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 381
Subcellular Localization Nucleus .
Protein Description Involved in spliceosome maturation and the first step of pre-mRNA splicing..
Protein Sequence MKRKAVLEAFSDSEDEDEKKLKGPQLITGFSAEEGVHYQNETIQRIHEKKRAPKIIHIASDENWMEKRKARFKKKETEVHEKPSQLPDSGLNYGLNIRVASSSAADNEIVDWKANNSNEKAQNKIATNKESTDILPEEVQLVLNDLNDDVKSANSANLQPITTNVVNEKDAYRKDIDELPEPSNMKDYSEIPVEEFGAAMLRGMGWNGQLSSKDAFDVNQRPTFLGMGAKPVDSELTELDIWKNPKKTMFLPVKPLESNSALNSQNEHTEVQKKSNSIDNLTPSSELFRKRSRDNNLSRESSVSSKHLDYNSRNYNKRDRDPDRTKYREYHSERRKQHRTDRYSDDYYQGRSYSYKKRSHRSDRYTERENPDRSYRSTRTL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationKAVLEAFSDSEDEDE
HHHHHHHCCCCCHHH		47.4728889911
13PhosphorylationVLEAFSDSEDEDEKK
HHHHHCCCCCHHHHH		45.8328889911
275PhosphorylationHTEVQKKSNSIDNLT
CHHHHHHHCCCCCCC		42.7328889911
277PhosphorylationEVQKKSNSIDNLTPS
HHHHHHCCCCCCCCC		38.1128889911
298PhosphorylationRSRDNNLSRESSVSS
HHCCCCCCCCHHCCH		35.8025720772
301PhosphorylationDNNLSRESSVSSKHL
CCCCCCCHHCCHHHC		34.6225720772
302PhosphorylationNNLSRESSVSSKHLD
CCCCCCHHCCHHHCC		22.6725720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPP2_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPP2_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPP2_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YF14_SCHPOSPAC9E9.04genetic
22681890
WTF16_SCHPOwtf16genetic
22681890
YHZ8_SCHPOSPBC21B10.08cgenetic
22681890
SWR1_SCHPOswr1genetic
22681890
FIS1_SCHPOfis1genetic
22681890
YQ7B_SCHPOSPCC1442.11cgenetic
22681890
ADG2_SCHPOadg2genetic
22681890
PFL4_SCHPOpfl4genetic
22681890
YN1B_SCHPOSPBC577.11genetic
22681890
CEK1_SCHPOcek1genetic
22681890
PYP1_SCHPOpyp1genetic
22681890
RAV2_SCHPOrav2genetic
22681890
MU122_SCHPOmug122genetic
22681890
YCT3_SCHPOSPCC794.03genetic
22681890
RL30A_SCHPOrpl3001genetic
22681890
CTBL1_SCHPOSPAC1952.06cgenetic
22681890
SNF30_SCHPOsnf30genetic
22681890
REXO3_SCHPOrex3genetic
22681890
YN8E_SCHPOSPBP35G2.14genetic
22681890
AP2M_SCHPOapm4genetic
22681890
PLB2_SCHPOSPAC1A6.03cgenetic
22681890
DUG1_SCHPOSPBC1198.08genetic
22681890
TYW2_SCHPOtrm12genetic
22681890
YQ72_SCHPOSPCC1442.02genetic
22681890
FEP1_SCHPOfep1genetic
22681890
YK82_SCHPObdf2genetic
22681890
CAT1_SCHPOcat1genetic
22681890
SKB5_SCHPOskb5genetic
22681890
YC1B_SCHPOmsy1genetic
22681890
MET10_SCHPOSPCC584.01cgenetic
22681890
YN25_SCHPOprt1genetic
22681890
ATS1_SCHPOats1genetic
22681890
MUG80_SCHPOmug80genetic
22681890
MBF1_SCHPOSPBC83.17genetic
22681890
ATF21_SCHPOatf21genetic
22681890
YM04_SCHPOSPAC212.04cgenetic
22681890
GAS5_SCHPOgas5genetic
22681890
PPR5_SCHPOppr5genetic
22681890
TSPO_SCHPOSPBC725.10genetic
22681890
QCR8_SCHPOqcr8genetic
22681890
YBPC_SCHPOSPBC16H5.12cgenetic
22681890
PAN3_SCHPOppk26genetic
22681890
FCF2_SCHPOfcf2genetic
22681890
YJFB_SCHPOSPCC306.11genetic
22681890
YLY4_SCHPOSPAC186.04cgenetic
22681890
TPSY_SCHPOSPAC22F8.05genetic
22681890
CTL1_SCHPOctl1genetic
22681890
TLS1_SCHPOtls1genetic
22681890
ING2_SCHPOpng2genetic
22681890
YKT4_SCHPOSPAPB1E7.04cgenetic
22681890
YJD1_SCHPOSPCC594.01genetic
22681890
YJM5_SCHPOSPCC1020.05genetic
22681890
YCPF_SCHPOSPCC663.15cgenetic
22681890
YCF8_SCHPOSPCC1393.08genetic
22681890
PPZ_SCHPOpzh1genetic
22681890
YEHG_SCHPOSPAC23H4.16cgenetic
22681890
MBX1_SCHPOmbx1genetic
22681890
HSP71_SCHPOssa1genetic
22681890
YQ9H_SCHPOSPCC18.17cgenetic
22681890
RL27A_SCHPOrpl2701genetic
22681890
MCP2_SCHPOmcp2genetic
22681890
MEU22_SCHPOmeu22genetic
22681890
GLD1_SCHPOgld1genetic
22681890
YQ9A_SCHPOSPCC18.10genetic
22681890
YI75_SCHPOSPAC977.05cgenetic
22681890
OCA2_SCHPOoca2genetic
22681890
YEYH_SCHPOmsy2genetic
22681890
RAP1_SCHPOrap1genetic
22681890
SUM2_SCHPOsum2genetic
22681890
SDE2_SCHPOsde2genetic
22681890
POF15_SCHPOpof15genetic
22681890
YDL6_SCHPOSPAC3A12.06cgenetic
22681890
MUG10_SCHPOmug10genetic
22681890
YOH8_SCHPOleo1genetic
22681890
KPR1_SCHPOSPAC4A8.14genetic
22681890
PRS10_SCHPOrpt4genetic
22681890
POZ1_SCHPOpoz1genetic
22681890
ASSY_SCHPOarg12genetic
22681890
YOX1_SCHPOyox1genetic
22681890
YI43_SCHPOSPBC1348.03genetic
22681890
MOC3_SCHPOmoc3genetic
22681890
TCG1_SCHPOtcg1genetic
22681890
ULP1_SCHPOulp1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPP2_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; SER-13; SER-275 ANDSER-277, AND MASS SPECTROMETRY.

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