FEX2_YEAST - dbPTM
FEX2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FEX2_YEAST
UniProt AC Q08991
Protein Name Fluoride export protein 2 {ECO:0000303|PubMed:24173035}
Gene Name FEX2 {ECO:0000303|PubMed:24173035}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 375
Subcellular Localization Cell membrane
Multi-pass membrane protein .
Protein Description Fluoride channel required for the rapid expulsion of cytoplasmic fluoride..
Protein Sequence MIFNPVISNHKLSHYIHVFCTFTTFCILGTETRQAITALSTYTPAFVTAPTVLWSNCSSCMLMGIMQSLNAYTWMKDHQVLFLGVTTGYCGALSSFSSMLLEMFEHSTNLTNGNIANHTKLPNRAYGIMEFLSVLLVHLMVSMGSLIFGRQLGKEVIVAYGSSSFSKPYTPPSDTVKENAGDVDTQEMEKNILEFKFKTPAPFFKKFFDVVDKLAYALAFPLIILFVVLCAYYENYSRGKWTLPCLFGIFAGFLRYWLAEMFNKTNKKFPLGTFLANVFATLLIGIFTMVQRGKKHFSTDIPIVNSLNSCHIVSALISGFCGTLSTISTFINEGYKLSFINMLIYYTVSIGISYCLLVITLGSYAWTRGLTNPIC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
109N-linked_GlycosylationEMFEHSTNLTNGNIA
HHHHHCCCCCCCCCC
-
117N-linked_GlycosylationLTNGNIANHTKLPNR
CCCCCCCCCCCCCCH
-
170PhosphorylationSSFSKPYTPPSDTVK
CCCCCCCCCCCHHCH
27214570
173PhosphorylationSKPYTPPSDTVKENA
CCCCCCCCHHCHHCC
21551504
175PhosphorylationPYTPPSDTVKENAGD
CCCCCCHHCHHCCCC
27717283
185PhosphorylationENAGDVDTQEMEKNI
HCCCCCCHHHHHHHH
27214570
235N-linked_GlycosylationVLCAYYENYSRGKWT
HHHHHHHHHCCCCCH
-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FEX2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FEX2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FEX2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SYIC_YEASTILS1genetic
27708008
TECR_YEASTTSC13genetic
27708008
MOB2_YEASTMOB2genetic
27708008
YIP1_YEASTYIP1genetic
27708008
NAB3_YEASTNAB3genetic
27708008
LSM2_YEASTLSM2genetic
27708008
AAR2_YEASTAAR2genetic
27708008
MAK5_YEASTMAK5genetic
27708008
CDK1_YEASTCDC28genetic
27708008
CDC10_YEASTCDC10genetic
27708008
ARP2_YEASTARP2genetic
27708008
TIM22_YEASTTIM22genetic
27708008
YRB1_YEASTYRB1genetic
27708008
PSF1_YEASTPSF1genetic
27708008
DAD1_YEASTDAD1genetic
27708008
RPC10_YEASTRPC11genetic
27708008
CDC37_YEASTCDC37genetic
27708008
RPB7_YEASTRPB7genetic
27708008
SLD5_YEASTSLD5genetic
27708008
TSC11_YEASTTSC11genetic
27708008
RSP5_YEASTRSP5genetic
27708008
CDC4_YEASTCDC4genetic
27708008
CAK1_YEASTCAK1genetic
27708008
CDC14_YEASTCDC14genetic
27708008
ALG2_YEASTALG2genetic
27708008
CDC20_YEASTCDC20genetic
27708008
PRP43_YEASTPRP43genetic
27708008
DBF2_YEASTDBF2genetic
27708008
OKP1_YEASTOKP1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
DNA2_YEASTDNA2genetic
27708008
STS1_YEASTSTS1genetic
27708008
RPC9_YEASTRPC17genetic
27708008
PRP21_YEASTPRP21genetic
27708008
DPOD2_YEASTPOL31genetic
27708008
ESS1_YEASTESS1genetic
27708008
KTHY_YEASTCDC8genetic
27708008
RFC2_YEASTRFC2genetic
27708008
CDC11_YEASTCDC11genetic
27708008
SWD2_YEASTSWD2genetic
27708008
GRC3_YEASTGRC3genetic
27708008
SEC22_YEASTSEC22genetic
27708008
CDC3_YEASTCDC3genetic
27708008
POB3_YEASTPOB3genetic
27708008
HMCS_YEASTERG13genetic
27708008
TAP42_YEASTTAP42genetic
27708008
CBF3B_YEASTCEP3genetic
27708008
GPI15_YEASTGPI15genetic
27708008
DPOA_YEASTPOL1genetic
27708008
BRX1_YEASTBRX1genetic
27708008
GPI2_YEASTGPI2genetic
27708008
RDS3_YEASTRDS3genetic
27708008
PSB5_YEASTPRE2genetic
27708008
BUR1_YEASTSGV1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FEX2_YEAST

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Related Literatures of Post-Translational Modification

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