TRPF_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TRPF_YEAST
• UniProt AC: P00912
• Protein Name: N-(5'-phosphoribosyl)anthranilate isomerase
• Gene Name: TRP1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 224
• Protein Sequence: MSVINFTGSSGPLVKVCGLQSTEAAECALDSDADLLGIICVPNRKRTIDPVIARKISSLVKAYKNSSGTPKYLVGVFRNQPKEDVLALVNDYGIDIVQLHGDESWQEYQEFLGLPVIKRLVFPKDCNILLSAASQKPHSFIPLFDSEAGGTGELLDWNSISDWVGRQESPESLHFMLAGGLTPENVGDALRLNGVIGVDVSGGVETNGVKDSNKIANFVKNAKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSVINFTGS ------CCEEECCCC	31.53	22369663
45	Ubiquitination	IICVPNRKRTIDPVI EEEECCCCCCCCHHH	61.61	22817900
55	Ubiquitination	IDPVIARKISSLVKA CCHHHHHHHHHHHHH	37.61	22817900
61	Ubiquitination	RKISSLVKAYKNSSG HHHHHHHHHHHCCCC	51.82	23749301
64	Ubiquitination	SSLVKAYKNSSGTPK HHHHHHHHCCCCCCC	56.03	23749301
220	Ubiquitination	NKIANFVKNAKK--- HHHHHHHHHHCC---	47.23	23749301

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TRPF_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TRPF_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TRPF_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TAT2_YEAST	TAT2	genetic	12869194
TAT1_YEAST	TAT1	genetic	10705462
TAT2_YEAST	TAT2	genetic	10705462
PP11_YEAST	SIT4	genetic	18357452
TAT1_YEAST	TAT1	genetic	18357452
TAT2_YEAST	TAT2	genetic	18357452
TAT1_YEAST	TAT1	genetic	19416971
TAT2_YEAST	TAT2	genetic	19416971
PDR12_YEAST	PDR12	genetic	12869194
ERG6_YEAST	ERG6	genetic	21623372
QCR7_YEAST	QCR7	genetic	21623372
KICH_YEAST	CKI1	genetic	21623372
ALY2_YEAST	ALY2	genetic	21908639
CAJ1_YEAST	CAJ1	genetic	21908639
UBP13_YEAST	UBP13	genetic	21908639
TAT1_YEAST	TAT1	genetic	21908639
GCN2_YEAST	GCN2	genetic	27864078
TAT2_YEAST	TAT2	genetic	27864078
KEL1_YEAST	KEL1	genetic	27708008
SWD1_YEAST	SWD1	genetic	27708008
PEX32_YEAST	PEX32	genetic	27708008
AIM4_YEAST	AIM4	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
UME6_YEAST	UME6	genetic	27708008
LCMT1_YEAST	PPM1	genetic	27708008
FKBP2_YEAST	FPR2	genetic	27708008
BCK2_YEAST	BCK2	genetic	27708008
IES1_YEAST	IES1	genetic	27708008
MON1_YEAST	MON1	genetic	27708008
MED5_YEAST	NUT1	genetic	27708008
PEX31_YEAST	PEX31	genetic	27708008
BGL2_YEAST	BGL2	genetic	27708008
KSP1_YEAST	KSP1	genetic	27708008
SNX4_YEAST	SNX4	genetic	27708008
PEX2_YEAST	PEX2	genetic	27708008
HOC1_YEAST	HOC1	genetic	27708008
HIR3_YEAST	HIR3	genetic	27708008
YKH5_YEAST	YKL075C	genetic	27708008
KAPC_YEAST	TPK3	genetic	27708008
DYHC_YEAST	DYN1	genetic	27708008
LGUL_YEAST	GLO1	genetic	27708008
ERG6_YEAST	ERG6	genetic	27708008
PSP2_YEAST	PSP2	genetic	27708008
MSC1_YEAST	MSC1	genetic	27708008
SOK2_YEAST	SOK2	genetic	27708008
TCB2_YEAST	TCB2	genetic	27708008
NST1_YEAST	NST1	genetic	27708008
SIN3_YEAST	SIN3	genetic	27708008
MDM12_YEAST	MDM12	genetic	27708008
TAT2_YEAST	TAT2	genetic	27708008
RTC1_YEAST	RTC1	genetic	27708008
CY1_YEAST	CYT1	genetic	27708008
DIA2_YEAST	DIA2	genetic	27708008
YPK9_YEAST	YPK9	genetic	27708008
VTS1_YEAST	VTS1	genetic	27708008
MRX11_YEAST	YPL041C	genetic	27708008
SGF11_YEAST	SGF11	genetic	27708008
MDL2_YEAST	MDL2	genetic	27708008
SPEE_YEAST	SPE3	genetic	27708008
MED1_YEAST	MED1	genetic	27708008
DBF20_YEAST	DBF20	genetic	27708008
HDA3_YEAST	HDA3	genetic	27708008
YMP0_YEAST	YMR010W	genetic	28057802
RL36A_YEAST	RPL36A	genetic	29158977

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.