SMA6_CAEEL - dbPTM
SMA6_CAEEL - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SMA6_CAEEL
UniProt AC Q09488
Protein Name Serine/threonine-protein kinase sma-6
Gene Name sma-6
Organism Caenorhabditis elegans.
Sequence Length 636
Subcellular Localization Membrane
Single-pass type I membrane protein .
Protein Description Involved in TGF-beta pathway. May be a receptor for daf-7..
Protein Sequence MNITFIFILIFGFFNTQKCSKDYDHFDDEDLALSIPKNAIGVPKEFRQQVLKEMKLRNRPNDILKNRCYCNYDQSICGNNMTCVKQDGAACYHAVEEVYNKAEKRMETLHKWGCATLERGSGASHLTCNSWRAAHHSPKSIGCCYEGNYCNKNLIPPAYVHHHKEKALQEKTDNPEDYDSPLENMTRGGKMFIMVFATVMSVFAVIGCIYLCITRAEEKSKARARAKTVSLKTESTYMESKSMLEDSGSGSGQAALIQRTVRQDLTIIKTIGQGRYGEVRKALYRGSYVAVKTFYTTDEDSWKNERDVYQTNMINHENILQFVAADIWSEEDSMTKMLLITDYHELGSLSDYLCREETLTTDEALRLIHSCICGIEHLHAAVHGTGSFRKPEIAHRDIKSKNIIVKRPNVCCIADLGLALRYQNDKILPEKFNVQVGTKRYMAPELISNKLNPKDFSQFKMADIYSMALVMWEVAIRVEVNTCEEVLTVDETSPDHSASSGIGESVSSSGNISRMHLQKTNVEGHSTSLKAKQHVPPFDGIVHNDPNFDEMNDVICVRRIRPPPDLAWKNVPALNELSKLMEDSWHSIPHFRHSALKLKKEMAELIKNPDRQNQSQRKVEFQQQDSGLVESATNQS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
80N-linked_GlycosylationDQSICGNNMTCVKQD
CCCCCCCCCEEEEEC
16.66-
184N-linked_GlycosylationDYDSPLENMTRGGKM
HCCCHHHHCCCCCCH
44.82-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SMA6_CAEEL !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SMA6_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SMA6_CAEEL !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SRA6_CAEELsra-6genetic
17897480
MEX6_CAEELmex-6genetic
17897480
PDI2_CAEELpdi-2genetic
17897480
ROCK_CAEELlet-502genetic
17897480
SEM5_CAEELsem-5genetic
17897480
TRA2_CAEELtra-2genetic
17897480
LAG3_CAEELsel-8genetic
17897480
CCNE_CAEELcye-1genetic
17897480
PAL1_CAEELpal-1genetic
17897480
SOP2_CAEELsop-2genetic
17897480
HDA1_CAEELhda-1genetic
17897480
LAM2_CAEELlam-2genetic
17897480
BAR1_CAEELbar-1genetic
17897480
BTF3_CAEELicd-1genetic
17897480
MOG5_CAEELmog-5genetic
17897480
ZYG9_CAEELzyg-9genetic
17897480
LRP_CAEELlrp-1genetic
17897480
SPD2_CAEELspd-2genetic
17897480
ITPR_CAEELitr-1genetic
17897480
LIN3_CAEELlin-3genetic
17897480
PHA4_CAEELpha-4genetic
17897480
MOM2_CAEELmom-2genetic
17897480
MPK1_CAEELmpk-1genetic
17897480
MED12_CAEELdpy-22genetic
17897480
HMG12_CAEELhmg-1.2genetic
17897480
PAR3_CAEELpar-3genetic
17897480
SEL10_CAEELsel-10genetic
17897480
EFN4_CAEELefn-4genetic
17897480
HMP2_CAEELhmp-2genetic
17897480
MPIP1_CAEELcdc-25.1genetic
17897480
EPI1_CAEELepi-1genetic
17897480
MUA3_CAEELmua-3genetic
17897480
14331_CAEELpar-5genetic
17897480
SPT6H_CAEELemb-5genetic
17897480
CAV1_CAEELcav-1genetic
17897480
SKN1_CAEELskn-1genetic
17897480
GLD1_CAEELgld-1genetic
17897480
PAR6_CAEELpar-6genetic
17897480
UNC62_CAEELunc-62genetic
17897480
MEX5_CAEELmex-5genetic
17897480
GSK3_CAEELgsk-3genetic
17897480
CHK1_CAEELchk-1genetic
17897480
VPS28_CAEELvps-28genetic
17897480
UNC52_CAEELunc-52genetic
17897480
PAT3_CAEELpat-3genetic
17897480
YWIE_CAEELZK546.14genetic
17897480
GAP2_CAEELgap-2genetic
17897480

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SMA6_CAEEL

loading...

Related Literatures of Post-Translational Modification

TOP