PAR3_CAEEL - dbPTM
PAR3_CAEEL - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PAR3_CAEEL
UniProt AC Q17353
Protein Name Partitioning defective protein 3
Gene Name par-3 {ECO:0000312|EMBL:AAB18670.1}
Organism Caenorhabditis elegans.
Sequence Length 1379
Subcellular Localization Cytoplasm . Cytoplasmic and cell periphery.
Protein Description In cooperation with pkc-3, required for establishing cell polarity and regulating spindle orientation in the early embryo. [PubMed: 8521491]
Protein Sequence MSASSTSSSSTSCPEGGEPSGSCKSSDEGESTLKKRMQQYGIASGYANSSISTLDRSQYQSLPLNGTRRVTVQFGRMKIVVPWKESDQTVGQLADAALLRYKKARGMANEDRIHVHRLECASDGGILDMDDVLEEVFDLNYDQILAITDEANGGSTTPTYSQIQKQQHHYAQPLPYARKFDGGPSTPIASAFGSVTVNHQAHRAASPYNVGFARSNSRDFAPQPTHSKERRDSVVEVSSFDQIPQSGLRVSTPKPSRQSEDVIDGKPMNQPILRSSLRTEASGSRTEEATPVKQSRVTLSPEVEKKLAEQDERKSERRKHYDKNPGRFARGSDRKSRITDALLDARDRIADQLESQNPAEETKSQMIRVKIDQGPMPGTSLVTFPPIPEKSENEKQLGIEVNAVFDESSELPGTSEPTKLSSVQIMKIEDGGRIAKDGRIRVGDCIVAIDGKPVDQMSIIRVRASISDLAAVTSRPVTLIINRSLESFLEQESSAKPIQSALQQANTQYIGHTTVVELIKSSNGFGFTVTGRETAKGERLFYIGTVKPYGVALGHLKSGDRLLEINGTPTGQWTQSEIVEKLKETMVGEKIKFLVSRVSQSAIMSTSASSENKENEETLKVVEEEKIPQKLPLPALMTPPVPKDTPALSPSGASRFEIVIPFINGSSSAGLGVSLKARVSKKSNGSKVDCGIFIKNVMHGGAAFKEGGLRVDDRIVGVEDIDLEPLDNREAQAALAKKLKEVGMISSNVRLTISRYNECNPGQISRDLSRITVDASSPSPSSRMSSHTAPDSLLPSPATRGTSSSGADSSHSRQSSASSAVPAVPARLTERDSIVSDGTSRNDESELPDSADPFNREGLGRKSLSEKRGMGAAADPQHIKLFQDIKHQRQNSAPTSSTQKRSKSQPRSSSQRNYRSPMKLVDLPTTAAASASTNSQNLDDSDMLNRRSQSMESINRPVESILRGTGQIPTGSSSKVQFMQAASPDQHPFPPGAALLRLKNEESRSRDKSRRKSMGNPFSAMRNFFGFGSKSRDASPEKTPTESVQLRSVERPKSIIDERNNGSSERAPPPLPPHQSQRRGSGGNVFVDYGEPYGLIPQYPHNTTSGYESYADSELYDRYAAHRYHPRGGPIIDEDEYIYRQQSTSGNSPINTSSYVNYGLPASNAYHVGSRIPPQTSSGSISKTSGAMRRVYPAEYDEDVAYHQQIPQQSTRYQQGSGSGRGNADYHHMFNSWFAYTGGGAVGAAPVIKSSYGSSPVRIAAASAIERGESFVVEPVSGSSASATDRRGRSTSSGAVASGSSSTGFQYAAKEKYADARSGKFNGGSTRLFIPRHGGGLSAAAFATNFGGEAYETRGGGAGGSPSQYRRRDQGPPHRFPQY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
59PhosphorylationSTLDRSQYQSLPLNG
CCCCHHHCCCCCCCC		11.0027067626
170PhosphorylationIQKQQHHYAQPLPYA
HHHHHCCCCCCCCCC		12.5727067626
206PhosphorylationHQAHRAASPYNVGFA
CCHHCCCCCCCCEEC		27.2530078680
208PhosphorylationAHRAASPYNVGFARS
HHCCCCCCCCEECCC		21.7127067626
215PhosphorylationYNVGFARSNSRDFAP
CCCEECCCCCCCCCC		35.4130078680
217PhosphorylationVGFARSNSRDFAPQP
CEECCCCCCCCCCCC		34.1830078680
233PhosphorylationHSKERRDSVVEVSSF
CCHHHCCCEEEEECC		26.6719530675
238PhosphorylationRDSVVEVSSFDQIPQ
CCCEEEEECCCCCCC		16.2819530675
239PhosphorylationDSVVEVSSFDQIPQS
CCEEEEECCCCCCCC		37.7119530675
300PhosphorylationKQSRVTLSPEVEKKL
CCCCCCCCHHHHHHH		15.0628854356
638PhosphorylationLPLPALMTPPVPKDT
CCCCCCCCCCCCCCC		25.8728854356
649PhosphorylationPKDTPALSPSGASRF
CCCCCCCCCCCCCCE		21.0828854356
651PhosphorylationDTPALSPSGASRFEI
CCCCCCCCCCCCEEE		43.5519530675
777PhosphorylationRITVDASSPSPSSRM
HEEECCCCCCCCCCC		30.9930078680
816PhosphorylationSSHSRQSSASSAVPA
CCCCCCCCCCCCCCC		24.6728854356
836PhosphorylationTERDSIVSDGTSRND
CCCCCCCCCCCCCCC		28.7530078680
1035PhosphorylationGSKSRDASPEKTPTE
CCCCCCCCCCCCCCC		37.5719060867
1039PhosphorylationRDASPEKTPTESVQL
CCCCCCCCCCCCEEC		33.5119530675
1041PhosphorylationASPEKTPTESVQLRS
CCCCCCCCCCEECCC		46.2319530675
1043PhosphorylationPEKTPTESVQLRSVE
CCCCCCCCEECCCCC		20.0319530675
1155PhosphorylationSPINTSSYVNYGLPA
CCCCCHHHCCCCCCC		7.7727067626
1226PhosphorylationSGRGNADYHHMFNSW
CCCCCCCHHHHHCCC		7.3927067626
1252PhosphorylationAPVIKSSYGSSPVRI
CCCHHHCCCCCCHHH		28.2827067626
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PAR3_CAEEL !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PAR3_CAEEL !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PAR3_CAEEL !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SUMO_CAEELsmo-1physical
18692475
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PAR3_CAEEL

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Related Literatures of Post-Translational Modification

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