GLD1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLD1_CAEEL
• UniProt AC: Q17339
• Protein Name: Female germline-specific tumor suppressor gld-1
• Gene Name: gld-1
• Organism: Caenorhabditis elegans.
• Sequence Length: 463
• Protein Description: RNA-binding protein which recognizes the 5'-UACUCAU-3' RNA consensus sequence. [PubMed: 24838563 Binds sequences in both the 5'coding and the 3'-UTR region of rme-2 mRNA]
• Protein Sequence: MPSCTTPTYGVSTQLESQSSESPSRSSVMTPTSLDGDNSPRKRFPIIDNVPADRWPSTRRDGWSSVRAPPPARLTLSTNNRHIMSPISSAYSQTPNSLLSPAMFNPKSRSIFSPTLPATPMSYGKSSMDKSLFSPTATEPIEVEATVEYLADLVKEKKHLTLFPHMFSNVERLLDDEIGRVRVALFQTEFPRVELPEPAGDMISITEKIYVPKNEYPDYNFVGRILGPRGMTAKQLEQDTGCKIMVRGKGSMRDKSKESAHRGKANWEHLEDDLHVLVQCEDTENRVHIKLQAALEQVKKLLIPAPEGTDELKRKQLMELAIINGTYRPMKSPNPARVMTAVPLLSPTPLRSSGPVLMSPTPGSGLPSTTFGGSILSPTLTASNLLGSNVFDYSLLSPSMFDSFSSLQLASDLTFPKYPTTTSFVNSFPGLFTSASSFANQTNTNVSPSGASPSASSVNNTSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	PSRSSVMTPTSLDGD CCCCCCCCCCCCCCC	22.66	30078680
32	Phosphorylation	RSSVMTPTSLDGDNS CCCCCCCCCCCCCCC	32.52	30078680
33	Phosphorylation	SSVMTPTSLDGDNSP CCCCCCCCCCCCCCC	26.18	30078680
39	Phosphorylation	TSLDGDNSPRKRFPI CCCCCCCCCCCCCCC	30.71	19060867
110	Phosphorylation	MFNPKSRSIFSPTLP HCCCCCCCCCCCCCC	34.77	30078680
113	Phosphorylation	PKSRSIFSPTLPATP CCCCCCCCCCCCCCC	18.46	30078680
115	Phosphorylation	SRSIFSPTLPATPMS CCCCCCCCCCCCCCC	44.14	30078680
119	Phosphorylation	FSPTLPATPMSYGKS CCCCCCCCCCCCCCC	19.99	30078680
122	Phosphorylation	TLPATPMSYGKSSMD CCCCCCCCCCCCCCC	31.75	30078680
123	Phosphorylation	LPATPMSYGKSSMDK CCCCCCCCCCCCCCC	23.48	30078680
346	Phosphorylation	MTAVPLLSPTPLRSS EEECCCCCCCCCCCC	34.12	28854356
348	Phosphorylation	AVPLLSPTPLRSSGP ECCCCCCCCCCCCCC	31.42	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLD1_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLD1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLD1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1G_CAEEL	eef-1G	physical	14704431
CUT2_CAEEL	cut-2	physical	14704431
UCR1_CAEEL	ucr-1	physical	14704431
VIT6_CAEEL	vit-6	physical	14704431
COL19_CAEEL	col-19	physical	14704431

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.