| UniProt ID | SAD1_SCHPO | |
|---|---|---|
| UniProt AC | Q09825 | |
| Protein Name | Spindle pole body-associated protein sad1 | |
| Gene Name | sad1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 514 | |
| Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane Single-pass membrane protein. |
|
| Protein Description | Associates with the spindle pole body and maintains a functional interface between the nuclear membrane and the microtubule motor proteins. Involved in chromosome segregation during meiosis where it associates with the telomeres.. | |
| Protein Sequence | MFTNTPVGGKRERQNGAHPAWSTLGANSAQIHQNTADLASKMHKLRYTKIRSPPTRVSIESITPKQRFPAPNFEQAYHSNIRYEQEESDNEEFENVVKNGHEASTNVFYESDGDDEEFVNEEYENSIDEESDDEGYSLNEDTTATNASFRYPMNQRSTRKSQFYSSKFKPLLWFGITLFSTLLIITLLHKGQEFYSRSFSSDNSQPSNSPVPNIPPASNDTKTSLKPDIIKDFTDSPSKVGGNEEFDYSTGDLITKKEFDKILQQKVEQLKQSLKEEMSNYKSSVPFEVELNDDWKFFIESTVRKYLTDPVSMPNFALLSTGAEVLPALTSKRYVRRPSAFIPRFTSYFFDSLVVRGHEPSIALTPNNAVAMCWSFQGSEGQLGISLSRPVYVTNVTIEHVQHKIAHDLSSAPKDFELWVQGMSSKMFVLLGKARYSLTEDSIQTFSFESSNYIVAEPIQNVILKIKSNWGNPNYTCLYQVRVHGTVPNADEQPIPSLGEKAESTAENTGQDSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MFTNTPVGGK -----CCCCCCCCCC | 36.56 | 29996109 | |
| 5 | Phosphorylation | ---MFTNTPVGGKRE ---CCCCCCCCCCCC | 19.12 | 29996109 | |
| 52 | Phosphorylation | LRYTKIRSPPTRVSI HHCCCCCCCCCEEEE | 38.41 | 24763107 | |
| 55 | Phosphorylation | TKIRSPPTRVSIESI CCCCCCCCEEEEEEC | 47.27 | 21712547 | |
| 58 | Phosphorylation | RSPPTRVSIESITPK CCCCCEEEEEECCHH | 19.83 | 24763107 | |
| 61 | Phosphorylation | PTRVSIESITPKQRF CCEEEEEECCHHHCC | 30.05 | 21712547 | |
| 63 | Phosphorylation | RVSIESITPKQRFPA EEEEEECCHHHCCCC | 33.44 | 21712547 | |
| 88 | Phosphorylation | IRYEQEESDNEEFEN CCEECCCCCCHHHHH | 45.01 | 28889911 | |
| 236 | Phosphorylation | IIKDFTDSPSKVGGN HHHHCCCCCCCCCCC | 28.19 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 236 | S | Phosphorylation | Kinase | CDC2 | P04551 | Uniprot |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SAD1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SAD1_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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