| UniProt ID | KMS1_SCHPO | |
|---|---|---|
| UniProt AC | P87245 | |
| Protein Name | Karyogamy meiotic segregation protein 1 | |
| Gene Name | kms1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 607 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body . Associates with the spindle pole body (SPB). | |
| Protein Description | Has a role in karyogamy, recombination and segregation during meiosis. Although it has been shown to associate with the spindle pole body it is unlikely to be involved in its formation or maintenance.. | |
| Protein Sequence | MLNERDFDLIFDSYDFKHEGKVHLSNFLPIINDLQLLHPASAPPLLSEFQKQCTLEFVRQNADLSITKDNFRDVYKKLTENEDDSFANQAEKPSMEQQNSKNSIKEDANEHSVNSAHSKSSSNASPESLNPSQMMSKRLSLPPMSQFTDSDFVNILRTPFAQSTPLNRNTSSRNTEMPLVRKDKPDFSNGHHDLIKQITELQDMLDKARDQARKKSRTVDILEGKVNELTHQLNMADSKYNESKVANNSQNNQIKTLKAQNLNIHKNFQKIQSELIQTNSGLYSTKKELSALQVRYATLLRKFTDQTKKIEELSLAASRSSENENTIRRLALENHELKNSNNQLNNHIDDLTREKHLIALSNNPKGDEFLSPSNLDEMVYSKEVGLSFTQPSVCISIPAVGMRESEELRELEFKCKQQKKTIEECKHISQSLQSSLTAESSRNKELVAGFLMLSEEIGIQKWIIQSLSKMSPTLNDFCRRYDSSMPTYEESSHECTVLSSFSDDETGLMATNTTMNNSSKDFMASQDTVNADNPHFLATKGQPLLLLSVMKSNILRLFYVLFLFACFYGLDYILCAELLQAFLRVVFTFCEHIIILLYGRYELVQPS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 115 | Phosphorylation | ANEHSVNSAHSKSSS HHHHCHHHHCCCCCC | 25.79 | 29996109 | |
| 118 | Phosphorylation | HSVNSAHSKSSSNAS HCHHHHCCCCCCCCC | 33.67 | 29996109 | |
| 525 | Phosphorylation | SSKDFMASQDTVNAD CCHHCCCCCCCCCCC | 19.46 | 24763107 | |
| 528 | Phosphorylation | DFMASQDTVNADNPH HCCCCCCCCCCCCCC | 14.18 | 24763107 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KMS1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KMS1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KMS1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SIF1_SCHPO | sif1 | physical | 14655046 | |
| UFE1_SCHPO | ufe1 | physical | 14655046 | |
| DYLT_SCHPO | dlc1 | physical | 14655046 | |
| SAD1_SCHPO | sad1 | physical | 14655046 | |
| DYLT_SCHPO | dlc1 | physical | 23401002 | |
| ALP4_SCHPO | alp4 | physical | 23401002 | |
| MBO1_SCHPO | mto1 | physical | 23401002 | |
| SPO11_SCHPO | rec12 | genetic | 24312672 | |
| ATM_SCHPO | tel1 | genetic | 24312672 | |
| RAD3_SCHPO | rad3 | genetic | 24312672 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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