CHR2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHR2_SCHPO
• UniProt AC: O94486
• Protein Name: Chitin synthase regulatory factor 2
• Gene Name: chr2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 512
• Subcellular Localization: Membrane ; Lipid-anchor .
• Protein Description: Involved in chitin biosynthesis..
• Protein Sequence: MLVSNGGTGSAHEWDRTTIDYDIEPSSDTHAIEISSNDDYLHPLAQFKKSEEFDEVPTNTLIHEVPSFSDSASNIQSQRNLSPFKELEIVSKKKSEQTFSSAVDFSAINVKNLNLKSGLFDPEPPSYDPDYAFNQRSLQSDPGSDEMFRNFKKSISLEELKSSYKLASAEMCEPETRLSFLQLALQAEKSSSRRNREYVARKKEEAFDYLTSFVSQGNSFFGYSEALYLLAVCYGTGALRTEINEKEAYRLYKMAADLNHVQAAYRVAICLQMGFGVTQNTEEAIHYFFRAASGQHVGAMHRMALIYFRGLMSVKRDPVKAMYYLNLGALEADHEFPQALYDLAELYEHGSSYLDGLLELSPRKAFVLYHIAAKYGLKDAQLRVARCFELGQLECDINLVRSFVWYRRLARKRNPEAMWKLSQFYLNGVDDVIYPNPELANEWAKAAAYKNHHLASTFVQDVGKEDVFEKTSITISNEERKSRNSESLPKKKKRLSMLSFKRSKNRESCIIS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Phosphorylation	PLAQFKKSEEFDEVP CHHHHCCCCCCCCCC	42.84	21712547
58	Phosphorylation	EEFDEVPTNTLIHEV CCCCCCCCCCEEEEC	46.11	29996109
60	Phosphorylation	FDEVPTNTLIHEVPS CCCCCCCCEEEECCC	29.57	29996109
67	Phosphorylation	TLIHEVPSFSDSASN CEEEECCCCCCCCHH	42.43	21712547
69	Phosphorylation	IHEVPSFSDSASNIQ EEECCCCCCCCHHHH	34.69	29996109
71	Phosphorylation	EVPSFSDSASNIQSQ ECCCCCCCCHHHHHH	32.19	21712547
73	Phosphorylation	PSFSDSASNIQSQRN CCCCCCCHHHHHHCC	38.12	29996109
77	Phosphorylation	DSASNIQSQRNLSPF CCCHHHHHHCCCCCC	27.58	27738172
82	Phosphorylation	IQSQRNLSPFKELEI HHHHCCCCCCHHHEE	31.66	28889911
91	Phosphorylation	FKELEIVSKKKSEQT CHHHEEEEECCCCCC	44.40	25720772
95	Phosphorylation	EIVSKKKSEQTFSSA EEEEECCCCCCHHHC	43.76	24763107
98	Phosphorylation	SKKKSEQTFSSAVDF EECCCCCCHHHCCCH	22.79	24763107
100	Phosphorylation	KKSEQTFSSAVDFSA CCCCCCHHHCCCHHH	22.30	21712547
101	Phosphorylation	KSEQTFSSAVDFSAI CCCCCHHHCCCHHHC	28.28	24763107
471	Phosphorylation	KEDVFEKTSITISNE CHHHHHHHEEEECHH	20.40	21712547
472	Phosphorylation	EDVFEKTSITISNEE HHHHHHHEEEECHHH	28.89	21712547
476	Phosphorylation	EKTSITISNEERKSR HHHEEEECHHHHHHC	29.55	28889911
482	Phosphorylation	ISNEERKSRNSESLP ECHHHHHHCCCCCCC	42.80	24763107
485	Phosphorylation	EERKSRNSESLPKKK HHHHHCCCCCCCHHH	27.70	28889911
487	Phosphorylation	RKSRNSESLPKKKKR HHHCCCCCCCHHHHH	50.20	21712547
496	Phosphorylation	PKKKKRLSMLSFKRS CHHHHHHHHHHHHCC	23.01	24763107
499	Phosphorylation	KKRLSMLSFKRSKNR HHHHHHHHHHCCCCC	21.78	24763107
509	Methylation	RSKNRESCIIS---- CCCCCCCCCCC----	2.47	-
509	Farnesylation	RSKNRESCIIS---- CCCCCCCCCCC----	2.47	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHR2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHR2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHR2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of CHR2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.