| UniProt ID | LEM2_SCHPO | |
|---|---|---|
| UniProt AC | Q10109 | |
| Protein Name | Lap-Emerin-Man domain protein 2 | |
| Gene Name | lem2 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 688 | |
| Subcellular Localization |
Nucleus inner membrane Multi-pass membrane protein . |
|
| Protein Description | Nucleus inner membrane protein involved in meiosis.. | |
| Protein Sequence | MDNWEDPNFELRNLRVIDLKKILHESGVSFPVNARKIEYIRMVDRIRKNKLSSGPQHLLSHLQKEENSNTSKASSSEDEIAPKYLYPSSPSKSTKKPHNETEPLLSPQFIDKPSNIETPVKIESPHVSQNNTFQSYSELSPNVETSLTMKTPPAHASTPKFRSHKSHRVAVPMSFMDSSALHTSPAFSERLKLLSSSNNFSPQLRSPKISHRLQTSATSSPLQHKRPFTNVPERVSRDIEFAPLDSARPSESSSPYSEVDSAEEDDELFQNYVLQQTRKESKLWSFIKKVFHDIKYANYRLLHNLRAFPGISAISSSYLVHIFMILLGVVAAIFLALLREKMFTAGFCDSGASGSSASILGISFPSLCRTCPPNAICPSPNYVECKPGYVLYEPWYSSLGFWPSKYCVSDTSREESVNIFREECLSVLRSWNAILHCSNNSSDLLERNMSYNAHPYVADNLNISSDHISFPSKPFALGLLHDTLLERKSPTLGLEMFEDLFKASLAVLSETNEVVMDSKLICYDSWAGIPLRCRLKQQLIKFVWRNKVFLFGILALSGVIFKLINFFRTRSIVAKYLPSASRFCVESLKRQKANYQMSRSQEPVIPLIEMHDILFHGNGPLEQIHMTKATARTLWEAIVERVEQVGSVRTRESEVDGEWTRVWEWVGTNTLDFQTDRSFINTTSPLRE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 74 | Phosphorylation | NSNTSKASSSEDEIA CCCCCCCCCCCCCCC | 25720772 | ||
| 75 | Phosphorylation | SNTSKASSSEDEIAP CCCCCCCCCCCCCCC | 25720772 | ||
| 76 | Phosphorylation | NTSKASSSEDEIAPK CCCCCCCCCCCCCCH | 29996109 | ||
| 88 | Phosphorylation | APKYLYPSSPSKSTK CCHHHCCCCCCCCCC | 29996109 | ||
| 89 | Phosphorylation | PKYLYPSSPSKSTKK CHHHCCCCCCCCCCC | 29996109 | ||
| 106 | Phosphorylation | NETEPLLSPQFIDKP CCCCCCCCHHHCCCC | 24763107 | ||
| 114 | Phosphorylation | PQFIDKPSNIETPVK HHHCCCCCCCCCCEE | 24763107 | ||
| 118 | Phosphorylation | DKPSNIETPVKIESP CCCCCCCCCEEECCC | 21712547 | ||
| 151 | Phosphorylation | ETSLTMKTPPAHAST EEEEEECCCCCCCCC | 24763107 | ||
| 157 | Phosphorylation | KTPPAHASTPKFRSH CCCCCCCCCCCHHCC | 24763107 | ||
| 158 | Phosphorylation | TPPAHASTPKFRSHK CCCCCCCCCCHHCCC | 21712547 | ||
| 166 | Phosphorylation | PKFRSHKSHRVAVPM CCHHCCCCCCEEEEC | 21712547 | ||
| 174 | Phosphorylation | HRVAVPMSFMDSSAL CCEEEECCCCCCHHH | 29996109 | ||
| 178 | Phosphorylation | VPMSFMDSSALHTSP EECCCCCCHHHCCCH | 29996109 | ||
| 179 | Phosphorylation | PMSFMDSSALHTSPA ECCCCCCHHHCCCHH | 21712547 | ||
| 183 | Phosphorylation | MDSSALHTSPAFSER CCCHHHCCCHHHHHH | 21712547 | ||
| 184 | Phosphorylation | DSSALHTSPAFSERL CCHHHCCCHHHHHHH | 21712547 | ||
| 188 | Phosphorylation | LHTSPAFSERLKLLS HCCCHHHHHHHHHHH | 29996109 | ||
| 195 | Phosphorylation | SERLKLLSSSNNFSP HHHHHHHHCCCCCCH | 25720772 | ||
| 196 | Phosphorylation | ERLKLLSSSNNFSPQ HHHHHHHCCCCCCHH | 25720772 | ||
| 197 | Phosphorylation | RLKLLSSSNNFSPQL HHHHHHCCCCCCHHH | 21712547 | ||
| 201 | Phosphorylation | LSSSNNFSPQLRSPK HHCCCCCCHHHCCCC | 24763107 | ||
| 206 | Phosphorylation | NFSPQLRSPKISHRL CCCHHHCCCCCHHHH | 24763107 | ||
| 210 | Phosphorylation | QLRSPKISHRLQTSA HHCCCCCHHHHCCCC | 21712547 | ||
| 215 | Phosphorylation | KISHRLQTSATSSPL CCHHHHCCCCCCCCC | 21712547 | ||
| 216 | Phosphorylation | ISHRLQTSATSSPLQ CHHHHCCCCCCCCCC | 21712547 | ||
| 218 | Phosphorylation | HRLQTSATSSPLQHK HHHCCCCCCCCCCCC | 21712547 | ||
| 219 | Phosphorylation | RLQTSATSSPLQHKR HHCCCCCCCCCCCCC | 24763107 | ||
| 220 | Phosphorylation | LQTSATSSPLQHKRP HCCCCCCCCCCCCCC | 25720772 | ||
| 678 | Phosphorylation | LDFQTDRSFINTTSP CCCCCCCHHCCCCCC | 29996109 | ||
| 682 | Phosphorylation | TDRSFINTTSPLRE- CCCHHCCCCCCCCC- | 29996109 | ||
| 683 | Phosphorylation | DRSFINTTSPLRE-- CCHHCCCCCCCCC-- | 28889911 | ||
| 684 | Phosphorylation | RSFINTTSPLRE--- CHHCCCCCCCCC--- | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LEM2_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LEM2_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LEM2_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MUG61_SCHPO | man1 | genetic | 21880100 | |
| SAD1_SCHPO | sad1 | physical | 26771498 | |
| MUG61_SCHPO | man1 | genetic | 26744419 | |
| IINMP_SCHPO | ima1 | genetic | 26744419 | |
| YBOE_SCHPO | csi1 | genetic | 26744419 | |
| YBM4_SCHPO | dsh1 | genetic | 26744419 | |
| TAZ1_SCHPO | taz1 | genetic | 26744419 | |
| JHD1_SCHPO | epe1 | genetic | 26744419 | |
| MST2_SCHPO | mst2 | genetic | 26744419 | |
| CLR3_SCHPO | clr3 | genetic | 26744419 | |
| CDS1_SCHPO | cds1 | genetic | 26746798 | |
| MRC1_SCHPO | mrc1 | genetic | 26746798 | |
| CHK1_SCHPO | chk1 | genetic | 26746798 | |
| RIR2_SCHPO | suc22 | genetic | 26746798 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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