S39A9_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S39A9_HUMAN
• UniProt AC: Q9NUM3
• Protein Name: Zinc transporter ZIP9
• Gene Name: SLC39A9
• Organism: Homo sapiens (Human).
• Sequence Length: 307
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: May act as a zinc-influx transporter..
• Protein Sequence: MDDFISISLLSLAMLVGCYVAGIIPLAVNFSEERLKLVTVLGAGLLCGTALAVIVPEGVHALYEDILEGKHHQASETHNVIASDKAAEKSVVHEHEHSHDHTQLHAYIGVSLVLGFVFMLLVDQIGNSHVHSTDDPEAARSSNSKITTTLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEVGGIGHSHKPDATGGRGLSRLEVAALVLGCLIPLILSVGHQH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	N-linked_Glycosylation	GIIPLAVNFSEERLK CHHHHHCCCCHHHHH	29.17	UniProtKB CARBOHYD
77	O-linked_Glycosylation	KHHQASETHNVIASD CCCCCCCCCCCCCCC	19.09	OGP
85	Ubiquitination	HNVIASDKAAEKSVV CCCCCCCHHHHHHCC	47.18	-
85	2-Hydroxyisobutyrylation	HNVIASDKAAEKSVV CCCCCCCHHHHHHCC	47.18	-
241	N-linked_Glycosylation	KEALSEVNATGVAML HHHHHHCCHHHHHHH	27.94	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S39A9_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S39A9_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S39A9_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CD44_HUMAN	CD44	physical	28514442
TTI2_HUMAN	TTI2	physical	28514442
FKRP_HUMAN	FKRP	physical	28514442
HIP1R_HUMAN	HIP1R	physical	28514442
DJC13_HUMAN	DNAJC13	physical	28514442
TPST2_HUMAN	TPST2	physical	28514442
SCMC1_HUMAN	SLC25A24	physical	28514442
OSTC_HUMAN	OSTC	physical	28514442
HPCL1_HUMAN	HPCAL1	physical	28514442
CANT1_HUMAN	CANT1	physical	28514442
SNG3_HUMAN	SYNGR3	physical	28514442
MET16_HUMAN	METTL16	physical	28514442
ECM29_HUMAN	KIAA0368	physical	28514442
SFXN5_HUMAN	SFXN5	physical	28514442
MTX3_HUMAN	MTX3	physical	28514442
TTK_HUMAN	TTK	physical	28514442
RMND1_HUMAN	RMND1	physical	28514442
GOLM1_HUMAN	GOLM1	physical	28514442
SRPRA_HUMAN	SRPR	physical	28514442
B4GT5_HUMAN	B4GALT5	physical	28514442
STIM1_HUMAN	STIM1	physical	28514442
COT2_HUMAN	NR2F2	physical	28514442
MTFP1_HUMAN	MTFP1	physical	28514442
CDC23_HUMAN	CDC23	physical	28514442
IDHP_HUMAN	IDH2	physical	28514442
PM34_HUMAN	SLC25A17	physical	28514442
HELLS_HUMAN	HELLS	physical	28514442
DYN1_HUMAN	DNM1	physical	28514442
ABCB8_HUMAN	ABCB8	physical	28514442
MSH3_HUMAN	MSH3	physical	28514442
PXMP2_HUMAN	PXMP2	physical	28514442
NEK7_HUMAN	NEK7	physical	28514442
PDXD1_HUMAN	PDXDC1	physical	28514442
MPC2_HUMAN	MPC2	physical	28514442
BDH_HUMAN	BDH1	physical	28514442
XPO7_HUMAN	XPO7	physical	28514442
RIF1_HUMAN	RIF1	physical	28514442
VPS50_HUMAN	CCDC132	physical	28514442
VAPB_HUMAN	VAPB	physical	28514442
MTX1_HUMAN	MTX1	physical	28514442
TBRG4_HUMAN	TBRG4	physical	28514442
MIC27_HUMAN	APOOL	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.