PXMP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PXMP2_HUMAN
• UniProt AC: Q9NR77
• Protein Name: Peroxisomal membrane protein 2
• Gene Name: PXMP2
• Organism: Homo sapiens (Human).
• Sequence Length: 195
• Subcellular Localization: Peroxisome membrane; Multi-pass membrane protein.
• Protein Description: Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane..
• Protein Sequence: MAPAASRLRAEAGLGALPRRALAQYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Phosphorylation	KKRKKENSRSLDVGG HHHHHHCCCCCCCCC	25.08	29116813
66	Phosphorylation	RKKENSRSLDVGGPL HHHHCCCCCCCCCCH	28.83	23312004
160	Phosphorylation	RMNWRVWTPLQFINI HCCEEEECCEEEEEC	15.97	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PXMP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PXMP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PXMP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PEX19_HUMAN	PEX19	physical	11590176
K1C40_HUMAN	KRT40	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.