B4GT5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: B4GT5_HUMAN
• UniProt AC: O43286
• Protein Name: Beta-1,4-galactosyltransferase 5
• Gene Name: B4GALT5
• Organism: Homo sapiens (Human).
• Sequence Length: 388
• Subcellular Localization: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.
• Protein Description: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids..
• Protein Sequence: MRARRGLLRLPRRSLLAALFFFSLSSSLLYFVYVAPGIVNTYLFMMQAQGILIRDNVRTIGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKLGGHWKPSDCMPRWKVAILIPFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIPESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPHHHRGEVQFLGRYALLRKSKERQGLDGLNNLNYFANITYDALYKNITVNLTPELAQVNEY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	LIRDNVRTIGAQVYE EEECCHHHHHHHHHH	21.34	-
59	O-linked_Glycosylation	LIRDNVRTIGAQVYE EEECCHHHHHHHHHH	21.34	46171049
71	Phosphorylation	VYEQVLRSAYAKRNS HHHHHHHHHHHHHCC	22.82	-
73	Phosphorylation	EQVLRSAYAKRNSSV HHHHHHHHHHHCCCC	17.57	-
75	Ubiquitination	VLRSAYAKRNSSVND HHHHHHHHHCCCCCC	39.16	27667366
77	N-linked_Glycosylation	RSAYAKRNSSVNDSD HHHHHHHCCCCCCCC	37.62	UniProtKB CARBOHYD
81	N-linked_Glycosylation	AKRNSSVNDSDYPLD HHHCCCCCCCCCCCC	45.04	UniProtKB CARBOHYD
90	N-linked_Glycosylation	SDYPLDLNHSETFLQ CCCCCCCCCCHHHHH	35.98	UniProtKB CARBOHYD
98	O-linked_Glycosylation	HSETFLQTTTFLPED CCHHHHHCCCCCCCH	29.92	OGP
111	N-linked_Glycosylation	EDFTYFANHTCPERL CHHCHHCCCCCCCCC	22.54	UniProtKB CARBOHYD
128	N-linked_Glycosylation	MKGPIDINMSEIGMD CCCCCCCCHHHHCHH	24.95	UniProtKB CARBOHYD
142	Phosphorylation	DYIHELFSKDPTIKL HHHHHHHCCCCCEEE	49.09	24719451
156	Phosphorylation	LGGHWKPSDCMPRWK ECCEECHHHCCCCCE	39.45	26074081
258	Ubiquitination	MPRHFATKLDKYMYL CCHHHHHHHHHHHHH	51.78	27667366
285	Ubiquitination	LTVEQFRKINGFPNA CCHHHHHHHCCCCCC	41.64	-
321	Phosphorylation	VSRPEGDTGKYKSIP CCCCCCCCCCCCCCC	46.56	30576142
323	Ubiquitination	RPEGDTGKYKSIPHH CCCCCCCCCCCCCCC	52.15	21906983
325	Ubiquitination	EGDTGKYKSIPHHHR CCCCCCCCCCCCCCC	45.45	22817900
364	N-linked_Glycosylation	NNLNYFANITYDALY CCCHHHHCCCHHHHH	19.75	UniProtKB CARBOHYD
373	N-linked_Glycosylation	TYDALYKNITVNLTP CHHHHHCCEEEECCH	22.93	UniProtKB CARBOHYD
375	Phosphorylation	DALYKNITVNLTPEL HHHHCCEEEECCHHH	16.85	-
388	Phosphorylation	ELAQVNEY------- HHHHHCCC-------	20.74	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of B4GT5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of B4GT5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of B4GT5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of B4GT5_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.