dbPTM

RPGF2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RPGF2_HUMAN
UniProt AC	Q9Y4G8
Protein Name	Rap guanine nucleotide exchange factor 2
Gene Name	RAPGEF2
Organism	Homo sapiens (Human).
Sequence Length	1499
Subcellular Localization	Cytoplasm. Cytoplasm, perinuclear region. Cell membrane. Late endosome. Cell junction. Associated with the synaptic plasma membrane. Colocalizes with ADRB1 at the plasma membrane. Synaptosome. Enriched in synaptic plasma membrane and neuronal cell bo
Protein Description	Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP. [PubMed: 23800469]
Protein Sequence	MKPLAIPANHGVMGQQEKHSLPADFTKLHLTDSLHPQVTHVSSSHSGCSITSDSGSSSLSDIYQATESEAGDMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEILCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELLTRLSEEKRNGAPHLPKIGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVGGRNKLKKILDKTRISILPQKPYNDIGIGQSQDDSIVGLRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVTATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSSFLNAKKLYEDAQMARKVKQYLSNLELEMDEESLQTLSLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQSLPQPQQQPPPAHKINQGLQVPAVSLYPSRKKVPVKDLPPFGINSPQALKKILSLSEEGSLERHKKQAEDTISNASSQLSSPPTSPQSSPRKGYTLAPSGTVDNFSDSGHSEISSRSSIVSNSSFDSVPVSLHDERRQRHSVSIVETNLGMGRMERRTMIEPDQYSLGSYAPMSEGRGLYATATVISSPSTEELSQDQGDRASLDAADSGRGSWTSCSSGSHDNIQTIQHQRSWETLPFGHTHFDYSGDPAGLWASSSHMDQIMFSDHSTKYNRQNQSRESLEQAQSRASWASSTGYWGEDSEGDTGTIKRRGGKDVSIEAESSSLTSVTTEETKPVPMPAHIAVASSTTKGLIARKEGRYREPPPTPPGYIGIPITDFPEGHSHPARKPPDYNVALQRSRMVARSSDTAGPSSVQQPHGHPTSSRPVNKPQWHKPNESDPRLAPYQSQGFSTEEDEDEQVSAV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
85	Phosphorylation	LPETAVDSEDDDDEE CCCCCCCCCCCCCHH	36.00	24275569
263	Phosphorylation	EHRELDRTGTRKGHI ECEECCCCCCCCCEE	42.44	23909892
265	Phosphorylation	RELDRTGTRKGHIVI EECCCCCCCCCEEEE	28.70	23909892
275	Phosphorylation	GHIVIKGTSERLTMH CEEEEEECCCCEEEH	23.55	-
276	Phosphorylation	HIVIKGTSERLTMHL EEEEEECCCCEEEHH	29.41	-
288	Phosphorylation	MHLVEEHSVVDPTFI EHHHHHCCCCCCHHH	27.41	-
293	Phosphorylation	EHSVVDPTFIEDFLL HCCCCCCHHHHHHHH	32.55	-
301	Phosphorylation	FIEDFLLTYRTFLSS HHHHHHHHHHHHHCC	17.07	-
302	Phosphorylation	IEDFLLTYRTFLSSP HHHHHHHHHHHHCCH	13.97	-
351	Phosphorylation	FEGDPAMTRFLEEFE CCCCHHHHHHHHHHH	22.00	17081983
380	Ubiquitination	LNIACAAKAKRRLMT HHHHHHHHHHHHHHH	35.60	-
382	Ubiquitination	IACAAKAKRRLMTLT HHHHHHHHHHHHHCC	37.03	-
387	Phosphorylation	KAKRRLMTLTKPSRE HHHHHHHHCCCCCCC	35.55	20068231
389	Phosphorylation	KRRLMTLTKPSREAP HHHHHHCCCCCCCCC	31.57	20068231
392	Phosphorylation	LMTLTKPSREAPLPF HHHCCCCCCCCCCCE	44.29	20068231
460	Phosphorylation	LRNNTHLSITVKTNL HHCCCCEEEEEECCH	14.49	25627689
462	Phosphorylation	NNTHLSITVKTNLFV CCCCEEEEEECCHHH	16.75	25627689
478	Phosphorylation	KELLTRLSEEKRNGA HHHHHHHCHHHHCCC	40.18	28270605
498	Phosphorylation	IGDIKKASRYSIPDL CCCHHHHHCCCCCCC	40.40	22199227
500	Phosphorylation	DIKKASRYSIPDLAV CHHHHHCCCCCCCCC	14.41	26657352
501	Phosphorylation	IKKASRYSIPDLAVD HHHHHCCCCCCCCCC	26.91	22199227
548	Ubiquitination	RISILPQKPYNDIGI CEEECCCCCCCCCCC	47.75	21906983
550	Phosphorylation	SILPQKPYNDIGIGQ EECCCCCCCCCCCCC	32.28	27642862
574	Phosphorylation	RQTKHIPTALPVSGT EECCCCCCCCCCCCC	39.98	28152594
579	Phosphorylation	IPTALPVSGTLSSSN CCCCCCCCCCCCCCC	24.91	23927012
581	Phosphorylation	TALPVSGTLSSSNPD CCCCCCCCCCCCCHH	18.89	26846344
583	Phosphorylation	LPVSGTLSSSNPDLL CCCCCCCCCCCHHHH	31.40	23401153
584	Phosphorylation	PVSGTLSSSNPDLLQ CCCCCCCCCCHHHHH	36.93	26846344
585	Phosphorylation	VSGTLSSSNPDLLQS CCCCCCCCCHHHHHH	49.35	23401153
592	Phosphorylation	SNPDLLQSHHRILDF CCHHHHHHCCEECCC	22.64	26846344
593	Ubiquitination	NPDLLQSHHRILDFS CHHHHHHCCEECCCC	10.98	22817900
597	Ubiquitination	LQSHHRILDFSATPD HHHCCEECCCCCCCC	5.69	22817900
602	Phosphorylation	RILDFSATPDLPDQV EECCCCCCCCCCHHH	19.01	22199227
619	Phosphorylation	VFKADQQSRYIMISK HEEHHCCCCEEEEEC	22.78	24719451
621	Phosphorylation	KADQQSRYIMISKDT EHHCCCCEEEEECCC	10.49	25693802
625	Phosphorylation	QSRYIMISKDTTAKE CCCEEEEECCCCHHH	13.70	20049867
628	Phosphorylation	YIMISKDTTAKEVVI EEEEECCCCHHHHHH	32.18	20049867
629	Phosphorylation	IMISKDTTAKEVVIQ EEEECCCCHHHHHHH	45.96	20049867
644	Phosphorylation	AIREFAVTATPDQYS HHHHHCCCCCCCCCC	22.76	-
682	Phosphorylation	LADRIQLSGRYYLKN HHHHHHHHHCEEECC	12.59	-
688	Ubiquitination	LSGRYYLKNNMETET HHHCEEECCCCCCCE	30.10	21963094
698	Phosphorylation	METETLCSDEDAQEL CCCCEECCHHHHHHH	47.34	28985074
703	Ubiquitination	LCSDEDAQELLRESQ ECCHHHHHHHHHHHH	54.94	22817900
709	Ubiquitination	AQELLRESQISLLQL HHHHHHHHHCHHHHH	26.78	22817900
733	Ubiquitination	SMRNFELFRNIEPTE HHHCHHHHCCCCCCH	4.41	21963094
737	Ubiquitination	FELFRNIEPTEYIDD HHHHCCCCCCHHHHH	50.12	21963094
789	Ubiquitination	LKRMKIIKHFIKIAL HHHHHHHHHHHHHHH	35.62	-
806	Phosphorylation	RECKNFNSMFAIISG HHCCCHHHHHHHHHC	15.90	-
824	O-linked_Glycosylation	APVARLRTTWEKLPN HHHHHHHHHHHHCCH	40.63	30059200
825	O-linked_Glycosylation	PVARLRTTWEKLPNK HHHHHHHHHHHCCHH	25.78	30059200
843	Ubiquitination	LFQDLQDLFDPSRNM HHHHHHHHHCCCHHH	3.19	21963094
849	Ubiquitination	DLFDPSRNMAKYRNV HHHCCCHHHHHHHHH	38.82	21963094
853	Phosphorylation	PSRNMAKYRNVLNSQ CCHHHHHHHHHHHCC	9.62	-
859	Phosphorylation	KYRNVLNSQNLQPPI HHHHHHHCCCCCCCC	19.11	-
875	Ubiquitination	PLFPVIKKDLTFLHE CCHHHEECCCEEEEC	47.01	29967540
896	Ubiquitination	DGLVNFEKLRMIAKE CCCCCHHHHHHHHHH	36.94	-
912	Phosphorylation	RHVGRMASVNMDPAL HHHHHHHCCCCCHHH	12.51	28857561
930	Phosphorylation	TRKKKWRSLGSLSQG CCCHHHHCCCCCCCC	35.65	22617229
933	Phosphorylation	KKWRSLGSLSQGSTN HHHHCCCCCCCCCCC	30.09	25072903
935	Phosphorylation	WRSLGSLSQGSTNAT HHCCCCCCCCCCCCE	33.90	17525332
938	Phosphorylation	LGSLSQGSTNATVLD CCCCCCCCCCCEEEH	15.73	29978859
939	Phosphorylation	GSLSQGSTNATVLDV CCCCCCCCCCEEEHH	35.38	29978859
942	Phosphorylation	SQGSTNATVLDVAQT CCCCCCCEEEHHHHH	24.54	24117733
949	Phosphorylation	TVLDVAQTGGHKKRV EEEHHHHHCCCHHHC	35.08	25954137
959	Phosphorylation	HKKRVRRSSFLNAKK CHHHCCHHHCCCHHH	18.19	30266825
960	Phosphorylation	KKRVRRSSFLNAKKL HHHCCHHHCCCHHHH	31.76	23401153
968	Phosphorylation	FLNAKKLYEDAQMAR CCCHHHHHHHHHHHH	22.20	29496907
976	Ubiquitination	EDAQMARKVKQYLSN HHHHHHHHHHHHHHH	44.22	-
978	Phosphorylation	AQMARKVKQYLSNLE HHHHHHHHHHHHHCC	35.94	32142685
1005	Phosphorylation	LQCEPATNTLPKNPG EEEECCCCCCCCCCC	41.55	32645325
1006	Phosphorylation	QCEPATNTLPKNPGD EEECCCCCCCCCCCC	39.83	-
1019	Phosphorylation	GDKKPVKSETSPVAP CCCCCCCCCCCCCCC	46.47	30266825
1021	Phosphorylation	KKPVKSETSPVAPRA CCCCCCCCCCCCCCC	45.48	30266825
1022	Phosphorylation	KPVKSETSPVAPRAG CCCCCCCCCCCCCCC	17.21	23401153
1060	Phosphorylation	GLQVPAVSLYPSRKK CCCCCCEEECCCCCC	25.05	28111955
1062	Phosphorylation	QVPAVSLYPSRKKVP CCCCEEECCCCCCCC	7.52	28111955
1064	Phosphorylation	PAVSLYPSRKKVPVK CCEEECCCCCCCCCC	43.08	28111955
1080	Phosphorylation	LPPFGINSPQALKKI CCCCCCCCHHHHHHH	19.23	30266825
1089	Phosphorylation	QALKKILSLSEEGSL HHHHHHHCCCCCCHH	33.07	28348404
1091	Phosphorylation	LKKILSLSEEGSLER HHHHHCCCCCCHHHH	30.17	30266825
1094	Phosphorylation	ILSLSEEGSLERHKK HHCCCCCCHHHHHHH	33.22	32142685
1095	Phosphorylation	LSLSEEGSLERHKKQ HCCCCCCHHHHHHHH	30.27	30266825
1106	Phosphorylation	HKKQAEDTISNASSQ HHHHHHHHHHHHHHH	20.15	28450419
1108	Phosphorylation	KQAEDTISNASSQLS HHHHHHHHHHHHHHC	28.56	28450419
1111	Phosphorylation	EDTISNASSQLSSPP HHHHHHHHHHHCCCC	23.91	28450419
1112	Phosphorylation	DTISNASSQLSSPPT HHHHHHHHHHCCCCC	32.50	26657352
1115	Phosphorylation	SNASSQLSSPPTSPQ HHHHHHHCCCCCCCC	32.91	25159151
1116	Phosphorylation	NASSQLSSPPTSPQS HHHHHHCCCCCCCCC	43.41	25159151
1119	Phosphorylation	SQLSSPPTSPQSSPR HHHCCCCCCCCCCCC	57.32	25159151
1120	Phosphorylation	QLSSPPTSPQSSPRK HHCCCCCCCCCCCCC	27.07	25159151
1121	Phosphorylation	LSSPPTSPQSSPRKG HCCCCCCCCCCCCCC	40.32	32645325
1123	Phosphorylation	SPPTSPQSSPRKGYT CCCCCCCCCCCCCEE	45.77	28450419
1124	Phosphorylation	PPTSPQSSPRKGYTL CCCCCCCCCCCCEEE	24.39	22115753
1125	Phosphorylation	PTSPQSSPRKGYTLA CCCCCCCCCCCEEEC	47.45	32142685
1129	Phosphorylation	QSSPRKGYTLAPSGT CCCCCCCEEECCCCC	11.13	27642862
1152	Phosphorylation	HSEISSRSSIVSNSS CCCCCCCCCCCCCCC	26.77	29978859
1153	Phosphorylation	SEISSRSSIVSNSSF CCCCCCCCCCCCCCC	26.37	29978859
1156	Phosphorylation	SSRSSIVSNSSFDSV CCCCCCCCCCCCCCC	29.35	20363803
1158	Phosphorylation	RSSIVSNSSFDSVPV CCCCCCCCCCCCCCC	25.52	29507054
1159	Phosphorylation	SSIVSNSSFDSVPVS CCCCCCCCCCCCCCC	37.01	21712546
1162	Phosphorylation	VSNSSFDSVPVSLHD CCCCCCCCCCCCCCH	26.72	28450419
1166	O-linked_Glycosylation	SFDSVPVSLHDERRQ CCCCCCCCCCHHHHH	17.57	30059200
1166	Phosphorylation	SFDSVPVSLHDERRQ CCCCCCCCCCHHHHH	17.57	28450419
1176	Phosphorylation	DERRQRHSVSIVETN HHHHHHCCEEEEECC	21.54	22617229
1178	Phosphorylation	RRQRHSVSIVETNLG HHHHCCEEEEECCCC	24.75	29978859
1193	Phosphorylation	MGRMERRTMIEPDQY CCCCCCCEECCCCCC	28.81	27732954
1200	Phosphorylation	TMIEPDQYSLGSYAP EECCCCCCCCCCCCC	17.16	23663014
1201	Phosphorylation	MIEPDQYSLGSYAPM ECCCCCCCCCCCCCC	22.18	23663014
1204	Phosphorylation	PDQYSLGSYAPMSEG CCCCCCCCCCCCCCC	24.34	23663014
1205	Phosphorylation	DQYSLGSYAPMSEGR CCCCCCCCCCCCCCC	16.96	23663014
1209	Phosphorylation	LGSYAPMSEGRGLYA CCCCCCCCCCCCEEE	35.52	23663014
1222	Phosphorylation	YATATVISSPSTEEL EEEEEEEECCCHHHH	31.68	27251275
1223	Phosphorylation	ATATVISSPSTEELS EEEEEEECCCHHHHC	16.25	28985074
1225	Phosphorylation	ATVISSPSTEELSQD EEEEECCCHHHHCCC	50.85	28857561
1226	Phosphorylation	TVISSPSTEELSQDQ EEEECCCHHHHCCCC	36.54	27251275
1230	Phosphorylation	SPSTEELSQDQGDRA CCCHHHHCCCCCCCH	34.68	30624053
1238	Phosphorylation	QDQGDRASLDAADSG CCCCCCHHCCHHHCC	27.89	30624053
1241	Phosphorylation	GDRASLDAADSGRGS CCCHHCCHHHCCCCC	20.61	32142685
1244	Phosphorylation	ASLDAADSGRGSWTS HHCCHHHCCCCCCCC	26.18	28270605
1248	Phosphorylation	AADSGRGSWTSCSSG HHHCCCCCCCCCCCC	26.31	28270605
1250	Phosphorylation	DSGRGSWTSCSSGSH HCCCCCCCCCCCCCC	22.89	28270605
1251	Phosphorylation	SGRGSWTSCSSGSHD CCCCCCCCCCCCCCC	13.02	28270605
1253	Phosphorylation	RGSWTSCSSGSHDNI CCCCCCCCCCCCCCC	37.18	28270605
1254	Phosphorylation	GSWTSCSSGSHDNIQ CCCCCCCCCCCCCCC	48.95	28985074
1256	Phosphorylation	WTSCSSGSHDNIQTI CCCCCCCCCCCCCEE	29.61	30576142
1262	Phosphorylation	GSHDNIQTIQHQRSW CCCCCCCEEEECCCC	20.86	28270605
1268	Phosphorylation	QTIQHQRSWETLPFG CEEEECCCCCCCCCC	23.77	28348404
1271	Phosphorylation	QHQRSWETLPFGHTH EECCCCCCCCCCCCC	33.21	28348404
1277	Phosphorylation	ETLPFGHTHFDYSGD CCCCCCCCCCCCCCC	25.31	28348404
1281	Phosphorylation	FGHTHFDYSGDPAGL CCCCCCCCCCCCCCC	17.38	32142685
1282	Phosphorylation	GHTHFDYSGDPAGLW CCCCCCCCCCCCCCE	38.27	28348404
1297	Phosphorylation	ASSSHMDQIMFSDHS ECCCCCHHHHCCCHH	22.82	32142685
1301	Phosphorylation	HMDQIMFSDHSTKYN CCHHHHCCCHHHHHH	19.62	32142685
1313	Phosphorylation	KYNRQNQSRESLEQA HHHHCHHCHHHHHHH	45.63	29449344
1316	Phosphorylation	RQNQSRESLEQAQSR HCHHCHHHHHHHHHH	35.78	21815630
1322	Phosphorylation	ESLEQAQSRASWASS HHHHHHHHHHHHHHH	32.60	27135362
1325	Phosphorylation	EQAQSRASWASSTGY HHHHHHHHHHHHCCC	23.28	28450419
1328	Phosphorylation	QSRASWASSTGYWGE HHHHHHHHHCCCCCC	23.36	28450419
1337	Phosphorylation	TGYWGEDSEGDTGTI CCCCCCCCCCCCCCE	38.89	27251275
1341	Phosphorylation	GEDSEGDTGTIKRRG CCCCCCCCCCEEECC	47.27	-
1343	Phosphorylation	DSEGDTGTIKRRGGK CCCCCCCCEEECCCE	25.97	-
1396	Phosphorylation	IARKEGRYREPPPTP CCCCCCCCCCCCCCC	30.13	26699800
1402	Phosphorylation	RYREPPPTPPGYIGI CCCCCCCCCCCCCCC	48.14	26699800
1406	Phosphorylation	PPPTPPGYIGIPITD CCCCCCCCCCCCCCC	11.18	27642862
1428	Phosphorylation	PARKPPDYNVALQRS CCCCCCCCCHHHHHH	19.81	27642862
1442	Phosphorylation	SRMVARSSDTAGPSS HHHHHCCCCCCCCCC	33.17	32142685
1481	Phosphorylation	SDPRLAPYQSQGFST CCCCCCCCCCCCCCC	18.39	24275569
1487	Phosphorylation	PYQSQGFSTEEDEDE CCCCCCCCCCCCCCC	41.56	23090842
1488	Phosphorylation	YQSQGFSTEEDEDEQ CCCCCCCCCCCCCCC	40.93	29507054
1497	Phosphorylation	EDEDEQVSAV----- CCCCCCCCCC-----	24.02	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
644	T	Phosphorylation	Kinase	PLK2	Q9NYY3	Uniprot
806	S	Phosphorylation	Kinase	PLK2	Q9NYY3	Uniprot
933	S	Phosphorylation	Kinase	PLK2	Q9NYY3	Uniprot
960	S	Phosphorylation	Kinase	PRKCQ	Q04759	GPS
1176	S	Phosphorylation	Kinase	PLK2	Q9NYY3	Uniprot
1244	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
1248	S	Phosphorylation	Kinase	CSNK1A1	P48729	GPS
1254	S	Phosphorylation	Kinase	IKBKB	O14920	GPS
-	K	Ubiquitination	E3 ubiquitin ligase	NEDD4	P46934	PMID:24340059:28405688:11598133

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RPGF2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RPGF2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GNDS_HUMAN	RALGDS	physical	7809086
RAP1A_HUMAN	RAP1A	physical	10934204
KIF5A_HUMAN	KIF5A	physical	20936779
KINH_HUMAN	KIF5B	physical	20936779
ATP8_HUMAN	ATP8	physical	20936779
PHOCN_HUMAN	MOB4	physical	20936779
NEDD4_HUMAN	NEDD4	physical	11598133
FBW1A_HUMAN	BTRC	physical	25332235
UBC_HUMAN	UBC	physical	25332235
FBW1B_HUMAN	FBXW11	physical	25332235
E41L5_HUMAN	EPB41L5	physical	25332235
KIF11_HUMAN	KIF11	physical	25332235
PTN13_HUMAN	PTPN13	physical	25332235
FLNC_HUMAN	FLNC	physical	25332235
LMNA_HUMAN	LMNA	physical	25332235
SCYL2_HUMAN	SCYL2	physical	25332235
MAGI1_HUMAN	MAGI1	physical	25332235
SND1_HUMAN	SND1	physical	25332235
KCD17_HUMAN	KCTD17	physical	25332235
MAGI3_HUMAN	MAGI3	physical	25332235
SSA27_HUMAN	SSSCA1	physical	25332235
STOM_HUMAN	STOM	physical	25332235
CTTB2_HUMAN	CTTNBP2	physical	25332235
KCTD5_HUMAN	KCTD5	physical	25332235
HMCN1_HUMAN	HMCN1	physical	25332235
PLEC_HUMAN	PLEC	physical	25332235
ZO1_HUMAN	TJP1	physical	25332235
TITIN_HUMAN	TTN	physical	25332235
AMPL_HUMAN	LAP3	physical	25332235
M2OM_HUMAN	SLC25A11	physical	25332235
TNKS1_HUMAN	TNKS	physical	25332235
XIAP_HUMAN	XIAP	physical	26496610
HD_HUMAN	HTT	physical	26496610
KPRA_HUMAN	PRPSAP1	physical	26496610
SEC62_HUMAN	SEC62	physical	26496610
UBP11_HUMAN	USP11	physical	26496610
COX5A_HUMAN	COX5A	physical	26496610
MESD_HUMAN	MESDC2	physical	26496610
WDR91_HUMAN	WDR91	physical	26496610
TRM6_HUMAN	TRMT6	physical	26496610
URFB1_HUMAN	UHRF1BP1	physical	26496610
BDP1_HUMAN	BDP1	physical	26496610
Z512B_HUMAN	ZNF512B	physical	26496610
ANO3_HUMAN	ANO3	physical	26496610
ERI3_HUMAN	ERI3	physical	26496610
USMG5_HUMAN	USMG5	physical	26496610
SP14L_HUMAN	SP140L	physical	26496610
LLR1_HUMAN	LRR1	physical	26496610
SR1IP_HUMAN	SREK1IP1	physical	26496610

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RPGF2_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome of resting human platelets."; Zahedi R.P., Lewandrowski U., Wiesner J., Wortelkamp S., Moebius J.,Schuetz C., Walter U., Gambaryan S., Sickmann A.; J. Proteome Res. 7:526-534(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1022; SER-1116 ANDTHR-1119, AND MASS SPECTROMETRY.	18088087 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-935, AND MASSSPECTROMETRY.	17525332 [Abstract]