| UniProt ID | HMCN1_HUMAN | |
|---|---|---|
| UniProt AC | Q96RW7 | |
| Protein Name | Hemicentin-1 | |
| Gene Name | HMCN1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 5635 | |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane . Cytoplasm . Cell junction . Cleavage furrow . The antibody used to determine subcellular location does not distinguish between HMCN1 and HMCN2. | |
| Protein Description | Promotes cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a role during myocardial remodeling by imparting an effect on cardiac fibroblast migration.. | |
| Protein Sequence | MISWEVVHTVFLFALLYSSLAQDASPQSEIRAEEIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLFNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRTHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEQAVNTWRIPFDPSLKEVTVSLSGPSPMIEIRNPLGKLIKKGFGLHELLNIHNSAKVVNVKEPEAGMWTVKTSSSGRHSVRITGLSTIDFRAGFSRKPTLDFKKTVSRPVQGIPTYVLLNTSGISTPARIDLLELLSISGSSLKTIPVKYYPHRKPYGIWNISDFVPPNEAFFLKVTGYDKDDYLFQRVSSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNINDVEFGIAFLNATITDSPNSDTRIIRAKITNVPRSLGSAMRKIVSILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEILQMSHIARGLDSDGSLLLDIVVSGYVLQLQSPAEVTVKDYTEDYIQTGPGQLYAYSTRLFTIDGISIPYTWNHTVFYDQAQGRMPFLVETLHASSVESDYNQIEETLGFKIHASISKGDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQVPKPCAHQCSNTPGSFKCICPPGQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQHYRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECKNTFGSYQCICPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFCLKNCPPNDLECALSPYALEYKLVSLPFGIATNQDLIRLVAYTQDGVMHPRTTFLMVDEEQTVPFALRDENLKGVVYTTRPLREAETYRMRVRASSYSANGTIEYQTTFIVYIAVSAYPY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MISWEVVHTV -----CCCHHHHHHH | 29.10 | 24043423 | |
| 9 | Phosphorylation | ISWEVVHTVFLFALL CCHHHHHHHHHHHHH | 11.01 | 24043423 | |
| 17 | Phosphorylation | VFLFALLYSSLAQDA HHHHHHHHHHHCCCC | 9.32 | 24043423 | |
| 18 | Phosphorylation | FLFALLYSSLAQDAS HHHHHHHHHHCCCCC | 20.88 | 24043423 | |
| 19 | Phosphorylation | LFALLYSSLAQDASP HHHHHHHHHCCCCCC | 17.73 | 24043423 | |
| 25 | Phosphorylation | SSLAQDASPQSEIRA HHHCCCCCCCHHCCH | 31.59 | 24043423 | |
| 28 | Phosphorylation | AQDASPQSEIRAEEI CCCCCCCHHCCHHHC | 38.07 | 24043423 | |
| 266 | Ubiquitination | EIRNPLGKLIKKGFG EEECHHHHHHHHCCC | 55.51 | - | |
| 285 | Acetylation | LNIHNSAKVVNVKEP HCCCCCCEEEECCCC | 46.68 | 7963395 | |
| 300 | Acetylation | EAGMWTVKTSSSGRH CCCEEEEEECCCCCE | 35.00 | 7963405 | |
| 349 | N-linked_Glycosylation | IPTYVLLNTSGISTP CCEEEEEECCCCCCH | 28.21 | UniProtKB CARBOHYD | |
| 390 | N-linked_Glycosylation | RKPYGIWNISDFVPP CCCCCCCCHHHCCCC | 23.20 | UniProtKB CARBOHYD | |
| 422 | Phosphorylation | FQRVSSVSFSSIVPD EEEEEEEEHHHCCCC | 22.74 | 30576142 | |
| 425 | Phosphorylation | VSSVSFSSIVPDAPK EEEEEHHHCCCCCCC | 26.12 | 30576142 | |
| 512 | Phosphorylation | AGTGRAQTFFDVSEP CCCCCCEEEEECCCC | 25.86 | - | |
| 528 | N-linked_Glycosylation | PVIQVPNNVTVTPGE CEEECCCCEEECCCH | 25.43 | UniProtKB CARBOHYD | |
| 530 | Phosphorylation | IQVPNNVTVTPGERA EECCCCEEECCCHHH | 22.30 | - | |
| 550 | N-linked_Glycosylation | IISAVDYNLTWQRND HEEECCCCCCCCCCC | 26.91 | UniProtKB CARBOHYD | |
| 573 | N-linked_Glycosylation | ARIRTLANLSLELKS HHHHHHHHCEEEEEE | 33.02 | UniProtKB CARBOHYD | |
| 620 | N-linked_Glycosylation | KVTVMPKNQSFTGGS CEEEECCCCCCCCCC | 36.54 | UniProtKB CARBOHYD | |
| 646 | Phosphorylation | PKPKIAWTVNDMFIV CCCEEEEEECCEEEE | 10.62 | - | |
| 693 | N-linked_Glycosylation | SAGTDKQNSTLRYIE CCCCCCCCCCEEEEE | 42.58 | UniProtKB CARBOHYD | |
| 745 | Phosphorylation | GDLELRPSTFLIIDP CCCCCCCCEEEEEHH | 25.92 | - | |
| 746 | Phosphorylation | DLELRPSTFLIIDPL CCCCCCCEEEEEHHH | 25.74 | - | |
| 809 | N-linked_Glycosylation | VSMEIGSNVTLPCYV EEEECCCCEEECEEE | 26.11 | UniProtKB CARBOHYD | |
| 878 | Phosphorylation | NQFGKIQSETTVTVT CCCCCCCCCEEEEEC | 40.14 | - | |
| 883 | Phosphorylation | IQSETTVTVTGLVAP CCCCEEEEECEEEHH | 15.40 | - | |
| 895 | Phosphorylation | VAPLIGISPSVANVI EHHHHCCCHHHHHHH | 13.10 | - | |
| 936 | Phosphorylation | AMLLQNPYITVRSDG HHHHCCCEEEEECCC | 19.44 | 22210691 | |
| 938 | Phosphorylation | LLQNPYITVRSDGSL HHCCCEEEEECCCCE | 12.20 | 22210691 | |
| 970 | N-linked_Glycosylation | SNVAGTNNKTTSVVV ECEECCCCCCEEEEE | 42.78 | UniProtKB CARBOHYD | |
| 1015 | Phosphorylation | PKPSVIWSKKGELIS CCCCEEEECCCCEEE | 17.23 | - | |
| 1112 | Phosphorylation | SLPPPIITWAKETQL CCCCCEEEEECCCCE | 21.79 | - | |
| 1124 | Phosphorylation | TQLISPFSPRHTFLP CCEECCCCCCCCCCC | 25.14 | 24945436 | |
| 1158 | N-linked_Glycosylation | VATNIAGNVTQAVKL EEEECCCCEEEEEEC | 25.33 | UniProtKB CARBOHYD | |
| 1272 | N-linked_Glycosylation | EDLEPPYNTTFQERV HHCCCCCCCCHHHHH | 38.12 | UniProtKB CARBOHYD | |
| 1351 | Phosphorylation | AGTTERKYNLKVHVP CCCCCCEEECEEECC | 31.76 | - | |
| 1369 | N-linked_Glycosylation | KDKEQVTNVSVLLNQ CCHHHHCCHHHHHHH | 25.80 | UniProtKB CARBOHYD | |
| 1429 | Phosphorylation | TPEDAGRYSCKAINI CHHHCCCCEEEEEEE | 19.94 | 29083192 | |
| 1430 | Phosphorylation | PEDAGRYSCKAINIA HHHCCCCEEEEEEEE | 14.05 | 29083192 | |
| 1523 | Phosphorylation | RRNDKGRYQCTVSNA CCCCCCCEEEEEECC | 19.33 | 23403867 | |
| 1526 | Phosphorylation | DKGRYQCTVSNAAGK CCCCEEEEEECCCCC | 16.08 | 23403867 | |
| 1528 | Phosphorylation | GRYQCTVSNAAGKQA CCEEEEEECCCCCCC | 11.55 | 23403867 | |
| 1552 | N-linked_Glycosylation | PPSIKGGNVTTDISV CCCCCCCCCCCCHHH | 36.31 | UniProtKB CARBOHYD | |
| 1563 | Phosphorylation | DISVLINSLIKLECE CHHHHHHHHHHHHHH | 25.20 | 24719451 | |
| 1630 | Phosphorylation | VAGTAEKSFHVDVYV CCCCCCEEEEEEEEC | 16.46 | - | |
| 1636 | Phosphorylation | KSFHVDVYVPPMIEG EEEEEEEECCCCCCC | 11.63 | - | |
| 1658 | Phosphorylation | KQVVIAHSLTLECKA CCEEEEEEEEEEEHH | 17.64 | - | |
| 1674 | Phosphorylation | GNPSPILTWLKDGVP CCCCCCEEEEECCCC | 29.48 | - | |
| 1710 | Phosphorylation | QEIDRGQYICVATSV EEECCCCEEEEEEEC | 10.10 | 29396449 | |
| 1715 | Phosphorylation | GQYICVATSVAGEKE CCEEEEEEECCCCCE | 11.88 | 29396449 | |
| 1716 | Phosphorylation | QYICVATSVAGEKEI CEEEEEEECCCCCEE | 10.55 | 29396449 | |
| 1831 | Phosphorylation | VPPTIKSSGLSERVV CCCCCCCCCCCCEEE | 38.46 | 24719451 | |
| 1834 | Phosphorylation | TIKSSGLSERVVVKY CCCCCCCCCEEEEEE | 27.21 | 24719451 | |
| 1840 | Acetylation | LSERVVVKYKPVALQ CCCEEEEEECCCCHH | 35.63 | 20167786 | |
| 1841 | Phosphorylation | SERVVVKYKPVALQC CCEEEEEECCCCHHH | 14.65 | 24719451 | |
| 1929 | N-linked_Glycosylation | EDAGKMLNETVLVSN HHHHHHCCCEEEECC | 39.12 | UniProtKB CARBOHYD | |
| 1966 | Phosphorylation | RLLSGSTSMTFLNRG EECCCCCCCCEECCC | 19.95 | - | |
| 1968 | Phosphorylation | LSGSTSMTFLNRGQI CCCCCCCCEECCCCE | 25.41 | - | |
| 2013 | Phosphorylation | LQVHVAPSISGSNNM EEEEECCCCCCCCCE | 21.46 | - | |
| 2101 | Phosphorylation | RDIDLRVYVPPNIMG CCCEEEEECCCCCCC | 10.78 | 24043423 | |
| 2112 | N-linked_Glycosylation | NIMGEEQNVSVLISQ CCCCCCCHHHHHHHH | 31.17 | UniProtKB CARBOHYD | |
| 2114 | Phosphorylation | MGEEQNVSVLISQAV CCCCCHHHHHHHHHH | 20.82 | 24043423 | |
| 2118 | Phosphorylation | QNVSVLISQAVELLC CHHHHHHHHHHHHHH | 14.13 | 24043423 | |
| 2127 | Phosphorylation | AVELLCQSDAIPPPT HHHHHHCCCCCCCCC | 28.19 | 24043423 | |
| 2134 | Phosphorylation | SDAIPPPTLTWLKDG CCCCCCCCEEECCCC | 42.46 | 24043423 | |
| 2136 | Phosphorylation | AIPPPTLTWLKDGHP CCCCCCEEECCCCCC | 31.09 | 24043423 | |
| 2155 | N-linked_Glycosylation | PGLSISENRSVLKIE CCCCCCCCCCEEEEE | 34.43 | UniProtKB CARBOHYD | |
| 2172 | Phosphorylation | QVQDTGRYTCEATNV EECCCCCEEEEEEEC | 19.65 | 26270265 | |
| 2173 | Phosphorylation | VQDTGRYTCEATNVA ECCCCCEEEEEEECC | 11.51 | 26270265 | |
| 2177 | Phosphorylation | GRYTCEATNVAGKTE CCEEEEEEECCCCCC | 14.13 | 26270265 | |
| 2239 | Phosphorylation | KKGSPVLTDSMGRVR ECCCCCEECCCCCEE | 26.68 | 22210691 | |
| 2241 | Phosphorylation | GSPVLTDSMGRVRIL CCCCEECCCCCEEEE | 20.22 | 22210691 | |
| 2249 | Phosphorylation | MGRVRILSGGRQLQI CCCEEEEECCCEEEE | 36.51 | - | |
| 2257 | Phosphorylation | GGRQLQISIAEKSDA CCCEEEEEEECCCHH | 11.64 | - | |
| 2267 | Phosphorylation | EKSDAALYSCVASNV CCCHHHHHHHHHHCC | 8.69 | - | |
| 2372 | Phosphorylation | AVNVAGMTDKKYDLS EEEECCCCCCCEEEE | 43.69 | - | |
| 2395 | N-linked_Glycosylation | GNHRSPENISVVEKN CCCCCCCCEEEEECC | 34.91 | UniProtKB CARBOHYD | |
| 2428 | Phosphorylation | FKDGWPVSLSNSVRI ECCCCEEECCCCEEE | 23.23 | 29083192 | |
| 2430 | Phosphorylation | DGWPVSLSNSVRILS CCCEEECCCCEEEEE | 21.39 | 29083192 | |
| 2432 | Phosphorylation | WPVSLSNSVRILSGG CEEECCCCEEEEECH | 14.92 | 29083192 | |
| 2562 | Phosphorylation | PAGHKSRSFSLNVFV CCCCCCCCEEEEEEE | 26.69 | 22210691 | |
| 2593 | Phosphorylation | TVILNSPTSLVCEAY EEEECCCCCEEEEEC | 34.22 | 22210691 | |
| 2594 | Phosphorylation | VILNSPTSLVCEAYS EEECCCCCEEEEECC | 23.37 | 22210691 | |
| 2689 | N-linked_Glycosylation | KEVKIKVNNTLTLEC CCEEEEECCEEEEEE | 30.66 | UniProtKB CARBOHYD | |
| 2691 | Phosphorylation | VKIKVNNTLTLECEA EEEEECCEEEEEEEE | 18.86 | 25072903 | |
| 2693 | Phosphorylation | IKVNNTLTLECEAYA EEECCEEEEEEEEEE | 20.62 | 25072903 | |
| 2699 | Phosphorylation | LTLECEAYAIPSASL EEEEEEEEECCCCCC | 5.25 | 25072903 | |
| 2703 | Phosphorylation | CEAYAIPSASLSWYK EEEEECCCCCCCEEE | 25.11 | 25072903 | |
| 2705 | Phosphorylation | AYAIPSASLSWYKDG EEECCCCCCCEEECC | 27.55 | 25072903 | |
| 2707 | Phosphorylation | AIPSASLSWYKDGQP ECCCCCCCEEECCCC | 26.34 | 25072903 | |
| 2709 | Phosphorylation | PSASLSWYKDGQPLK CCCCCCEEECCCCCC | 8.88 | 25072903 | |
| 2738 | Phosphorylation | QIKEAQISDTGRYTC EEEEEEECCCCCEEE | 19.62 | - | |
| 2740 | Phosphorylation | KEAQISDTGRYTCVA EEEEECCCCCEEEEE | 19.44 | - | |
| 2876 | Phosphorylation | PIIKGANSDLPEEVT CCCCCCCCCCCHHEE | 39.73 | 24400094 | |
| 2883 | Phosphorylation | SDLPEEVTVLVNKSA CCCCHHEEEEECHHH | 16.05 | 24400094 | |
| 2887 | N-linked_Glycosylation | EEVTVLVNKSALIEC HHEEEEECHHHHHHH | 28.53 | UniProtKB CARBOHYD | |
| 2888 | Acetylation | EVTVLVNKSALIECL HEEEEECHHHHHHHH | 29.62 | 7685229 | |
| 2889 | Phosphorylation | VTVLVNKSALIECLS EEEEECHHHHHHHHH | 24.09 | 22210691 | |
| 2897 | Phosphorylation | ALIECLSSGSPAPRN HHHHHHHCCCCCCCC | 30.27 | 22210691 | |
| 2899 | Phosphorylation | IECLSSGSPAPRNSW HHHHHCCCCCCCCCC | 21.60 | 22210691 | |
| 2973 | N-linked_Glycosylation | VIGPKSENLTVVVNN HCCCCCCCEEEEECC | 48.37 | UniProtKB CARBOHYD | |
| 3197 | Phosphorylation | KRIENSDSLEVRILS CCCCCCCCEEEEEEC | 26.67 | 22210691 | |
| 3221 | N-linked_Glycosylation | SQHSDSGNYTCIASN CCCCCCCCEEEEEEC | 32.65 | UniProtKB CARBOHYD | |
| 3300 | N-linked_Glycosylation | ERIRVSANGSTLNIY EEEEEECCCCEEEEE | 37.12 | UniProtKB CARBOHYD | |
| 3530 | N-linked_Glycosylation | VLEPPHINGSEEHEE ECCCCCCCCCCCCCE | 44.92 | UniProtKB CARBOHYD | |
| 3645 | Phosphorylation | QVTLECKSDAVPPPV EEEEEECCCCCCCCE | 42.32 | 24719451 | |
| 3654 | Phosphorylation | AVPPPVITWLRNGER CCCCCEEEEEECCCC | 20.76 | 24719451 | |
| 3689 | N-linked_Glycosylation | ADLGDTANYTCVASN CCCCCCCCCEEEEEC | 34.44 | UniProtKB CARBOHYD | |
| 3691 | Phosphorylation | LGDTANYTCVASNIA CCCCCCCEEEEECCC | 10.58 | - | |
| 3695 | Phosphorylation | ANYTCVASNIAGKTT CCCEEEEECCCCCCE | 14.36 | - | |
| 3721 | Phosphorylation | NIKGGPQSLVILLNK CCCCCCCEEEEEECC | 27.95 | 19664995 | |
| 3727 | N-linked_Glycosylation | QSLVILLNKSTVLEC CEEEEEECCCHHHHH | 32.55 | UniProtKB CARBOHYD | |
| 3741 | Phosphorylation | CIAEGVPTPRITWRK HHHCCCCCCCEEEEC | 23.85 | 24719451 | |
| 3781 | Phosphorylation | HVTDTGRYLCMATNA EECCCCCEEEEEECC | 12.95 | - | |
| 3786 | Phosphorylation | GRYLCMATNAAGTDR CCEEEEEECCCCCCC | 9.86 | - | |
| 3791 | Phosphorylation | MATNAAGTDRRRIDL EEECCCCCCCEEEEE | 22.93 | - | |
| 3812 | N-linked_Glycosylation | SIAPGPTNMTVIVNV CCCCCCCCEEEEEEE | 27.53 | UniProtKB CARBOHYD | |
| 4029 | N-linked_Glycosylation | QKEGINVNTSGRNHA EECCEECCCCCCCCE | 24.84 | UniProtKB CARBOHYD | |
| 4030 | Phosphorylation | KEGINVNTSGRNHAV ECCEECCCCCCCCEE | 28.42 | - | |
| 4040 | Phosphorylation | RNHAVLPSGGLQISR CCCEECCCCCCEECC | 41.13 | - | |
| 4046 | Phosphorylation | PSGGLQISRAVREDA CCCCCEECCCHHHCC | 10.96 | - | |
| 4323 | Phosphorylation | ERVSKEDSGTYVCTA EEECHHHCCEEEEEE | 33.84 | 24719451 | |
| 4329 | Phosphorylation | DSGTYVCTAENSVGF HCCEEEEEECCCCEE | 27.28 | 24719451 | |
| 4333 | Phosphorylation | YVCTAENSVGFVKAI EEEEECCCCEEEEEE | 18.34 | 24719451 | |
| 4401 | N-linked_Glycosylation | HRIRQLGNGSLAIYG HHHHHCCCCCEEEEE | 45.53 | UniProtKB CARBOHYD | |
| 4491 | N-linked_Glycosylation | DRVNVLSNNSLYIAD HCEEEECCCCEEEEC | 37.64 | UniProtKB CARBOHYD | |
| 4606 | N-linked_Glycosylation | TRSCGRGNQTRTRTC HHHCCCCCCCCCEEC | 38.39 | UniProtKB CARBOHYD | |
| 4894 | N-linked_Glycosylation | EFGIAFLNATITDSP EEEEEEEECEECCCC | 28.69 | UniProtKB CARBOHYD | |
| 4928 | Phosphorylation | SAMRKIVSILNPIYW HHHHHHHHHHCCCCC | 25.49 | 27461979 | |
| 4934 | Phosphorylation | VSILNPIYWTTAKEI HHHHCCCCCCCHHHH | 9.65 | 27461979 | |
| 4936 | Phosphorylation | ILNPIYWTTAKEIGE HHCCCCCCCHHHHHH | 10.41 | 27461979 | |
| 4937 | Phosphorylation | LNPIYWTTAKEIGEA HCCCCCCCHHHHHHH | 22.91 | 27461979 | |
| 5040 | N-linked_Glycosylation | ISIPYTWNHTVFYDQ EECCCCEEEEEEEEC | 17.10 | UniProtKB CARBOHYD | |
| 5267 | N-linked_Glycosylation | NGMTKAENGTCIDID CCCEECCCCCEEEHH | 56.80 | UniProtKB CARBOHYD | |
| 5391 | Phosphorylation | PQQHYRQYSHLYSSY CCHHHHHHHHHHHCH | 6.78 | 25072903 | |
| 5392 | Phosphorylation | QQHYRQYSHLYSSYS CHHHHHHHHHHHCHH | 9.93 | 25072903 | |
| 5395 | Phosphorylation | YRQYSHLYSSYSEYR HHHHHHHHHCHHHHH | 7.08 | 25072903 | |
| 5396 | Phosphorylation | RQYSHLYSSYSEYRN HHHHHHHHCHHHHHC | 29.21 | 25072903 | |
| 5397 | Phosphorylation | QYSHLYSSYSEYRNS HHHHHHHCHHHHHCC | 21.08 | 25072903 | |
| 5398 | Phosphorylation | YSHLYSSYSEYRNSR HHHHHHCHHHHHCCC | 10.28 | 25072903 | |
| 5399 | Phosphorylation | SHLYSSYSEYRNSRT HHHHHCHHHHHCCCC | 30.05 | 25072903 | |
| 5401 | Phosphorylation | LYSSYSEYRNSRTSL HHHCHHHHHCCCCCH | 14.78 | 25072903 | |
| 5409 | Phosphorylation | RNSRTSLSRTRRTIR HCCCCCHHHHHHHHH | 31.23 | 22798277 | |
| 5567 | Phosphorylation | DGVMHPRTTFLMVDE CCCCCCCEEEEECCC | 26.76 | 27794612 | |
| 5568 | Phosphorylation | GVMHPRTTFLMVDEE CCCCCCEEEEECCCC | 18.95 | 27794612 | |
| 5592 | Phosphorylation | ENLKGVVYTTRPLRE CCCCCCEEECCCCCC | 10.45 | 28348404 | |
| 5593 | Phosphorylation | NLKGVVYTTRPLREA CCCCCEEECCCCCCC | 12.52 | 24719451 | |
| 5594 | Phosphorylation | LKGVVYTTRPLREAE CCCCEEECCCCCCCE | 16.77 | 28348404 | |
| 5602 | Phosphorylation | RPLREAETYRMRVRA CCCCCCEEEEEEEEE | 24.39 | 22210691 | |
| 5603 | Phosphorylation | PLREAETYRMRVRAS CCCCCEEEEEEEEEE | 8.23 | 22210691 | |
| 5612 | Phosphorylation | MRVRASSYSANGTIE EEEEEEECCCCCEEE | 14.87 | 29759185 | |
| 5613 | Phosphorylation | RVRASSYSANGTIEY EEEEEECCCCCEEEE | 19.73 | 29759185 | |
| 5615 | N-linked_Glycosylation | RASSYSANGTIEYQT EEEECCCCCEEEEEE | 42.05 | UniProtKB CARBOHYD |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HMCN1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HMCN1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HMCN1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CLP1_HUMAN | CLP1 | physical | 26344197 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| 603075 | Macular degeneration, age-related, 1 (ARMD1) | |||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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